Specific immunotherapy modifies allergen-specific CD4+ T-cell responses in an epitope-dependent manner - Wambre, Erik; DeLong, Jonathan H.; James, Eddie A.; Torres-Chinn, Nadia; Pfützner, Wolfgang; Möbs, Christian; Durham, Stephen R.; Till, Stephen J.; Robinson, David; Kwok, William W. (Journal of allergy and clinical immunology, 2014)
Keywords: Allergens - immunology; Allergies; allergy; Allergy and Immunology; Biological and medical sciences; CD4; CD4-Positive T-Lymphocytes - immunology; Cytokines; Desensitization, Immunologic; epitope; Epitopes, T-Lymphocyte - immunology; ex vivo; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Grasses; Humans; Immune Tolerance; Immunopathology; Immunophenotyping; Immunotherapy; Lymphocytes; Medical sciences; Peptides; peptide–MHC class II tetramer; peripheral tolerance; Phleum - immunology; pollen; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Statistical analysis; T cell receptors; T cells; Th1 Cells - immunology; Th2 Cells - immunology; Tumor Necrosis Factor Receptor Superfamily, Member 7 - analysis; ASIT; pollen; pMHCII; allergy; peripheral tolerance; T cells; CD4; PE; Immunotherapy; peptide–MHC class II tetramer; ex vivo; epitope; TGP; Allergen-specific immunotherapy; Timothy grass pollen; Peptide–MHC class II; Phycoerythrin; Allergy; Immunopathology; CD4 T lymphocyte; Immune response; Antigenic determinant; Peptides; Major histocompatibility system; Class II histocompatibility antigen; Tolerance; Immunology; Treatment; peptide-MHC class II tetramer; Ex vivo; Tetramer; T-Lymphocyte; Pollen; Allergen