The Toxicology of Mercury and Its Chemical Compounds

This review covers the toxicology of mercury and its compounds. Special attention is paid to those forms of mercury of current public health concern. Human exposure to the vapor of metallic mercury dates back to antiquity but continues today in occupational settings and from dental amalgam. Health r...

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Published in	Critical reviews in toxicology Vol. 36; no. 8; pp. 609 - 662
Main Authors	Clarkson, Thomas W., Magos, Laszlo
Format	Journal Article
Language	English
Published	Colchester Informa UK Ltd 01.09.2006 Taylor & Francis Informa Healthcare Taylor & Francis Ltd
Subjects	Animal tissues Animals Bioaccumulation Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Dental Amalgam Ethylmercury Health risks Humans Inorganic Mercury Medical sciences Mercury Mercury - blood Mercury - chemistry Mercury - metabolism Mercury Compounds - chemistry Mercury Compounds - metabolism Mercury Compounds - poisoning Mercury Poisoning - diagnosis Mercury Poisoning - etiology Mercury Poisoning - prevention & control Mercury Vapor Metals and various inorganic compounds Methylmercury Models, Biological No-Observed-Adverse-Effect Level Phenylmercury Preservatives Preservatives, Pharmaceutical - chemistry Public health Thimerosal Thimerosal - chemistry Toxicology Vapor Ethylmercury Inorganic Mercury Toxicity Dental Amalgam Review Mercury compound Epidemiology Case history Methylmercury Mercury Organic compounds Mercury Vapor Public health Human Thiomersal Use Mercury II Thimerosal Amalgams Metabolism Phenylmercury Heavy metal Toxicokinetics Antiseptic Pollution source Environment Tooth Mercury
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Abstract	This review covers the toxicology of mercury and its compounds. Special attention is paid to those forms of mercury of current public health concern. Human exposure to the vapor of metallic mercury dates back to antiquity but continues today in occupational settings and from dental amalgam. Health risks from methylmercury in edible tissues of fish have been the subject of several large epidemiological investigations and continue to be the subject of intense debate. Ethylmercury in the form of a preservative, thimerosal, added to certain vaccines, is the most recent form of mercury that has become a public health concern. The review leads to general discussion of evolutionary aspects of mercury, protective and toxic mechanisms, and ends on a note that mercury is still an "element of mystery."
AbstractList	This review covers the toxicology of mercury and its compounds. Special attention is paid to those forms of mercury of current public health concern. Human exposure to the vapor of metallic mercury dates back to antiquity but continues today in occupational settings and from dental amalgam. Health risks from methylmercury in edible tissues of fish have been the subject of several large epidemiological investigations and continue to be the subject of intense debate. Ethylmercury in the form of a preservative, thimerosal, added to certain vaccines, is the most recent form of mercury that has become a public health concern. The review leads to general discussion of evolutionary aspects of mercury, protective and toxic mechanisms, and ends on a note that mercury is still an "element of mystery." This review covers the toxicology of mercury and its compounds. Special attention is paid to those forms of mercury of current public health concern. Human exposure to the vapor of metallic mercury dates back to antiquity but continues today in occupational settings and from dental amalgam. Health risks from methylmercury in edible tissues of fish have been the subject of several large epidemiological investigations and continue to be the subject of intense debate. Ethylmercury in the form of a preservative, thimerosal, added to certain vaccines, is the most recent form of mercury that has become a public health concern. The review leads to general discussion of evolutionary aspects of mercury, protective and toxic mechanisms, and ends on a note that mercury is still an "element of mystery."This review covers the toxicology of mercury and its compounds. Special attention is paid to those forms of mercury of current public health concern. Human exposure to the vapor of metallic mercury dates back to antiquity but continues today in occupational settings and from dental amalgam. Health risks from methylmercury in edible tissues of fish have been the subject of several large epidemiological investigations and continue to be the subject of intense debate. Ethylmercury in the form of a preservative, thimerosal, added to certain vaccines, is the most recent form of mercury that has become a public health concern. The review leads to general discussion of evolutionary aspects of mercury, protective and toxic mechanisms, and ends on a note that mercury is still an "element of mystery."
Author	Magos, Laszlo Clarkson, Thomas W.
Author_xml	– sequence: 1 givenname: Thomas W. surname: Clarkson fullname: Clarkson, Thomas W. organization: Department of Environmental Medicine, University of Rochester School of Medicine, Rochester, New York, USA – sequence: 2 givenname: Laszlo surname: Magos fullname: Magos, Laszlo organization: Department of Environmental Medicine, University of Rochester School of Medicine, Rochester, New York, USA
BackLink	http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18169838$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/16973445$$D View this record in MEDLINE/PubMed
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Keywords	Vapor Ethylmercury Inorganic Mercury Toxicity Dental Amalgam Review Mercury compound Epidemiology Case history Methylmercury Mercury Organic compounds Mercury Vapor Public health Human Thiomersal Use Mercury II Thimerosal Amalgams Metabolism Phenylmercury Heavy metal Toxicokinetics Antiseptic Pollution source Environment Tooth Mercury
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SubjectTerms	Animal tissues Animals Bioaccumulation Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Dental Amalgam Ethylmercury Health risks Humans Inorganic Mercury Medical sciences Mercury Mercury - blood Mercury - chemistry Mercury - metabolism Mercury Compounds - chemistry Mercury Compounds - metabolism Mercury Compounds - poisoning Mercury Poisoning - diagnosis Mercury Poisoning - etiology Mercury Poisoning - prevention & control Mercury Vapor Metals and various inorganic compounds Methylmercury Models, Biological No-Observed-Adverse-Effect Level Phenylmercury Preservatives Preservatives, Pharmaceutical - chemistry Public health Thimerosal Thimerosal - chemistry Toxicology
Title	The Toxicology of Mercury and Its Chemical Compounds
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