Anti-human-TIGIT agonistic antibody ameliorates autoimmune diseases by inhibiting Tfh and Tph cells and enhancing Treg cells - Kojima, Marenori; Suzuki, Katsuya; Takeshita, Masaru; Ohyagi, Masaki; Iizuka, Mana; Yamane, Humitsugu; Koga, Keiko; Kouro, Taku; Kassai, Yoshiaki; Yoshihara, Tomoki; Adachi, Ryutaro; Hashikami, Kentarou; et al. (Communications biology, 2023)
Keywords: 13/31; 64/60; 692/4023/1670/1613; 692/4023/1670/498; Agonistic behavior; Animals; Antibodies, Monoclonal - pharmacology; Autoimmune diseases; Autoimmune Diseases - drug therapy; Biology; Biomedical and Life Sciences; CD4 antigen; Cell activation; Immunoglobulins; Immunoreceptor tyrosine-based inhibition motif; Immunoregulation; Life Sciences; Lymphocytes; Lymphocytes T; Mice; Monoclonal antibodies; Receptors, Immunologic - genetics; Signal Transduction; T-Lymphocytes, Regulatory