Interaction between Schwann cells and other cells during repair of peripheral nerve injury

• Published in: Neural regeneration research Vol. 16; no. 1; pp. 93 - 98
• Main Authors: Qu, Wen-Rui, Zhu, Zhe, Liu, Jun, Song, De-Biao, Tian, Heng, Chen, Bing-Peng, Li, Rui, Deng, Ling-Xiao
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.01.2021; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Department of Hand Surgery,the Second Hospital of Jilin University,Changchun,Jilin Province,China%Department of Emergency and Critical Medicine,the Second Hospital of Jilin University,Changchun,Jilin Province,China%Orthopedic Medical Center,the Second Hospital of Jilin University,Changchun,Jilin Province,China%Spinal Cord and Brain Injury Research Group,Stark Neurosciences Research Institute,Department of Neurological Surgery,Indiana University School of Medicine,Indianapolis,IN,USA; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: axon regeneration; cell-cell interactions; nerve injury; nerve repair; peripheral nerve; recovery; regeneration; repair; schwann cell migration; Cell interactions; Development and progression; Fibroblasts; Health aspects; Nerve regeneration; Neurological research; Peripheral nervous system diseases; Physiological aspects; Review; Schwann cells; China; repair; Schwann cell migration; peripheral nerve; regeneration; nerve injury; axon regeneration; nerve repair; recovery; cell-cell interactions
• ISSN: 1673-5374; 1876-7958
• DOI: 10.4103/1673-5374.286956

Peripheral nerve injury (PNI) is common and, unlike damage to the central nervous system injured nerves can effectively regenerate depending on the location and severity of injury. Peripheral myelinating glia, Schwann cells (SCs), interact with various cells in and around the injury site and are imp...