Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism - Mosconi, Lisa; Brys, Miroslaw; Switalski, Remigiusz; Mistur, Rachel; Glodzik, Lidia; Pirraglia, Elizabeth; Tsui, Wai; De Santi, Susan; de Leon, Mony J (Proceedings of the National Academy of Sciences - PNAS, 2007)
Keywords: Aged; Aged, 80 and over; Alzheimer disease; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - epidemiology; Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer's disease; Alzheimers disease; apolipoprotein E; Apolipoprotein E4 - genetics; Biological Sciences; brain; Brain Mapping; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - metabolism; Cognition & reasoning; cortex; Dementia; education; Effects; Family history; Female; Fluorine Radioisotopes - pharmacokinetics; Fluorodeoxyglucose F18 - pharmacokinetics; gender; Genes, Mitochondrial; Genetic Heterogeneity; Genetic Predisposition to Disease; Genetics; Genomic Imprinting; genotype; Genotypes; Glucose; Glucose - metabolism; Humans; Magnetic Resonance Imaging; Male; memory; Metabolism; Middle Aged; Mitochondrial DNA; Mothers; Neurology; Parents; Parietal lobe; patients; Positron emission tomography; Predisposing factors; Retrospective Studies; Risk; Risk factors; tomography