Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis - Rosendahl, Jonas; Witt, Heiko; Szmola, Richárd; Bhatia, Eesh; Ózsvári, Béla; Landt, Olfert; Schulz, Hans-Ulrich; Gress, Thomas M; Pfützer, Roland; Löhr, Matthias; Kovacs, Peter; Blüher, Matthias; et al. (Nature genetics, 2008)
Keywords: Agriculture; Animal Genetics and Genomics; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Cancer Research; Cell Line; Cell physiology; Chymotrypsin; Chymotrypsin - chemistry; Chymotrypsin - genetics; Chymotrypsin - metabolism; Diagnosis; Fundamental and applied biological sciences. Psychology; Gastroenterology. Liver. Pancreas. Abdomen; Gene expression; Gene Function; Genetic aspects; Genetic variation; Genetics; Genetics of eukaryotes. Biological and molecular evolution; Germany; Human Genetics; Humans; Inflammatory diseases; letter; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Medical sciences; Models, Molecular; Molecular and cellular biology; Molecular Sequence Data; Mutation; Other diseases. Semiology; Pancreas; Pancreatitis; Pancreatitis, Alcoholic - genetics; Pancreatitis, Chronic - genetics; Physiological aspects; Risk factors; Secretion. Exocytosis; Germany; India; Variant; Peptidases; Chronic; Serine endopeptidases; Chymotrypsin C; Enzyme; Secretion; Pancreatitis; Hydrolases; Digestive diseases; Pancreatic disease