SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load - Mourier, Tobias; Shuaib, Muhammad; Hala, Sharif; Mfarrej, Sara; Alofi, Fadwa; Naeem, Raeece; Alsomali, Afrah; Jorgensen, David; Subudhi, Amit Kumar; Ben Rached, Fathia; Guan, Qingtian; Salunke, Rahul P.; et al. (Nature communications, 2022)
Keywords: 13/106; 13/109; 38/109; 38/77; 38/88; 38/90; 38/91; 42/44; 45/43; 45/70; 631/208/325/2483; 631/326/596/4130; 692/699/255/2514; 82/1; 82/29; 82/58; 82/80; 82/83; Biochemical analysis; Coronavirus Nucleocapsid Proteins - genetics; Coronavirus Nucleocapsid Proteins - metabolism; Coronaviruses; COVID-19; COVID-19 - enzymology; COVID-19 - genetics; COVID-19 - virology; Gene sequencing; Genome, Viral; Genomes; Glycogen Synthase Kinase 3 - genetics; Glycogen Synthase Kinase 3 - metabolism; Host-Pathogen Interactions; Humanities and Social Sciences; Humans; Interferon; Kinases; multidisciplinary; Mutants; Mutation; Mutation, Missense; N protein; Nucleocapsid - genetics; Nucleocapsid - metabolism; Nucleocapsids; Pandemics; Phosphorylation; Phylogeny; Population dynamics; Protein Binding; Proteins; SARS-CoV-2 - classification; SARS-CoV-2 - genetics; SARS-CoV-2 - physiology; Saudi Arabia; Science; Science (multidisciplinary); Severe acute respiratory syndrome coronavirus 2; Therapeutic targets; Transcriptomes; Viral diseases; Viral Load; Virus Replication; Whole genome sequencing; Saudi Arabia