Structure and function relationship of OqxB efflux pump from Klebsiella pneumoniae - Bharatham, Nagakumar; Bhowmik, Purnendu; Aoki, Maho; Okada, Ui; Sharma, Sreevalli; Yamashita, Eiki; Shanbhag, Anirudh P.; Rajagopal, Sreenath; Thomas, Teby; Sarma, Maitrayee; Narjari, Riya; Nagaraj, Savitha; et al. (Nature communications, 2021)
Keywords: 119/118; 38/70; 38/77; 631/326/1320; 631/326/22/1434; 631/535/1266; 631/535/1267; 82/80; 82/81; 82/83; Amino acids; Anti-Bacterial Agents - pharmacology; Antibiotic resistance; Antibiotics; Bacterial Proteins - chemistry; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Binding; Binding Sites - genetics; Ciprofloxacin; Clinical isolates; Complementation; Computer applications; Crystal structure; Crystallography, X-Ray; Drug resistance; Drug Resistance, Multiple, Bacterial - genetics; E coli; Efflux; Enterobacter cloacae; Escherichia coli; Fluoroquinolones; Gene transfer; Gram-negative bacteria; Horizontal transfer; Humanities and Social Sciences; Klebsiella; Klebsiella pneumoniae; Klebsiella pneumoniae - genetics; Klebsiella pneumoniae - metabolism; Membrane Transport Proteins - chemistry; Membrane Transport Proteins - genetics; Membrane Transport Proteins - metabolism; Microbial Sensitivity Tests; Minimum inhibitory concentration; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular structure; multidisciplinary; Multidrug resistance; Nodulation; Protein Binding; Protein Conformation; Protein Multimerization; Salmonella; Science; Science (multidisciplinary); Structural analysis; Structure-Activity Relationship; Structure-function relationships; Substrates