Beneficial effects of fermented black ginseng and its ginsenoside 20(S)-Rg3 against cisplatin-induced nephrotoxicity in LLC-PK1 cells

• Published in: Journal of ginseng research Vol. 40; no. 2; pp. 135 - 140
• Main Authors: Han, Myoung-Sik, Han, Im-Ho, Lee, Dahae, An, Jun Min, Kim, Su-Nam, Shin, Myoung-Sook, Yamabe, Noriko, Hwang, Gwi Seo, Yoo, Hye Hyun, Choi, Suk-Jung, Kang, Ki Sung, Jang, Hyuk-Jai
• Format: Journal Article
• Language: English
• Published: Korea (South) Elsevier B.V 01.04.2016; 고려인삼학회; Elsevier
• Subjects: cisplatin; ginsenoside 20(S)-Rg3; mitogen-activated protein kinases; nephrotoxicity; Panax ginseng; 기타의약학; ginsenoside 20(S)-Rg3; nephrotoxicity; cisplatin; Panax ginseng; mitogen-activated protein kinases

Nephrotoxicity is a common side effect of medications. Panax ginseng is one of the best-known herbal medicines, and its individual constituents enhance renal function. Identification of its efficacy and mechanisms of action against drug-induced nephrotoxicity, as well as the specific constituents me...