Protective effect of total and supplemental vitamin C intake on the risk of hip fracture—a 17-year follow-up from the Framingham Osteoporosis Study

• Published in: Osteoporosis international Vol. 20; no. 11; pp. 1853 - 1861
• Main Authors: Sahni, S, Hannan, M. T, Gagnon, D, Blumberg, J, Cupples, L. A, Kiel, D. P, Tucker, K. L
• Format: Journal Article
• Language: English
• Published: London London : Springer-Verlag 01.11.2009; Springer-Verlag; Springer; Springer Nature B.V
• Subjects: Aged; Aged, 80 and over; Ascorbic Acid - administration & dosage; Biological and medical sciences; Bone Density - drug effects; Confounding Factors, Epidemiologic; Diet - statistics & numerical data; Dietary Supplements; Diseases of the osteoarticular system; Endocrinology; Epidemiologic Methods; Female; Fractures; Hip Fractures - epidemiology; Hip Fractures - etiology; Hip Fractures - prevention & control; Humans; Injuries of the limb. Injuries of the spine; Male; Massachusetts - epidemiology; Medical sciences; Medicine; Medicine & Public Health; Middle Aged; Older people; Original Article; Orthopedics; Osteoporosis - complications; Osteoporosis - epidemiology; Osteoporosis - prevention & control; Osteoporosis. Osteomalacia. Paget disease; Osteoporotic Fractures - epidemiology; Osteoporotic Fractures - etiology; Osteoporotic Fractures - prevention & control; Potassium, Dietary - administration & dosage; Rheumatology; Risk factors; Traumas. Diseases due to physical agents; Vitamin C; Massachusetts; Population studies; Fracture; Bone; Nutrition; Ageing; Vitamin C; Diseases of the osteoarticular system; Rheumatology; Vitamin; Trauma; Hip; Feeding; Prevention; Osteoporosis; Risk factor
• ISSN: 0937-941X; 1433-2965; 1433-2965
• DOI: 10.1007/s00198-009-0897-y

Summary Vitamin C may play a role in bone health. In the Framingham Study, subjects with higher total or supplemental vitamin C intake had fewer hip fractures and non-vertebral fractures as compared to subjects with lower intakes. Therefore, vitamin C may have a protective effect on bone health in o...