A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer - Saito, Tomoko; Niida, Atsushi; Uchi, Ryutaro; Hirata, Hidenari; Komatsu, Hisateru; Sakimura, Shotaro; Hayashi, Shuto; Nambara, Sho; Kuroda, Yosuke; Ito, Shuhei; Eguchi, Hidetoshi; Masuda, Takaaki; et al. (Nature communications, 2018)
Keywords: 45; 45/23; 631/67/1504/1885; 631/67/2329; Adenoma; Adenoma - genetics; Adenoma - metabolism; Adenomatous polyposis coli; Adenomatous Polyposis Coli Protein - genetics; Bayes Theorem; Biological Evolution; Cancer; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - genetics; Colorectal Neoplasms - metabolism; Disease Progression; Evolution; Evolution, Molecular; Exome; Gene Frequency; Genetic Heterogeneity; Heterogeneity; High-Throughput Nucleotide Sequencing; Humanities and Social Sciences; Humans; Lesions; multidisciplinary; Mutation; Proto-Oncogene Proteins p21(ras) - genetics; Science; Science (multidisciplinary); Sequence Analysis, DNA; Time Factors; Tumorigenesis; Tumors