Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility - Haller, Gabe; Torgerson, Dara G.; Ober, Carole; Thompson, Emma E. (Journal of allergy and clinical immunology, 2009)
Keywords: Accuracy; African Americans; Allergy and Immunology; Asthma; Asthma - genetics; Asthma - immunology; Biological and medical sciences; Black or African American - genetics; Chromosomes; Chronic obstructive pulmonary disease, asthma; Deoxyribonucleic acid; Disease; DNA; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Gene Frequency - genetics; Gene Frequency - immunology; Gene polymorphism; Genes; Genetic diversity; Genetic Predisposition to Disease; Genotype; Genotyping; Humans; Hypotheses; IgE; IL4; Immunopathology; Interleukin 4; Interleukin-4 - genetics; Interleukin-4 - immunology; Introns - genetics; Linkage Disequilibrium - genetics; Medical sciences; Pneumology; Polymorphism, Single Nucleotide - genetics; Polymorphism, Single Nucleotide - immunology; Population; private alleles; Rare variants; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Single-nucleotide polymorphism; Studies; IL4; MAF; SNP; private alleles; IgE; Rare variants; African Americans; asthma; Single nucleotide polymorphism; Minor allele frequency; Genetic variability; Non coding sequence; Interleukin 4; Immunology; Bronchus disease; Genetics; Obstructive pulmonary disease; Locus; Sequencing; Human; Lung disease; Immunopathology; Nucleotide sequence; Respiratory disease; Cytokine; Genotype; Asthma; Variant; Allele; Sensitivity; African American