Angiogenesis and neuronal remodeling after ischemic stroke

• Published in: Neural regeneration research Vol. 15; no. 1; pp. 16 - 19
• Main Authors: Hatakeyama, Masahiro, Ninomiya, Itaru, Kanazawa, Masato
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.01.2020; Medknow Publications & Media Pvt. Ltd; Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Angiogenesis; angiogenesis; axonal outgrowth; cerebral ischemia; coupling; functional recovery; guidance; neurogenesis; stroke; Brain research; Brain-derived neurotrophic factor; Cell adhesion & migration; Extracellular matrix; Fibroblasts; Hypoxia; Ischemia; Metabolism; Neurogenesis; Proteins; Review; Stroke; Vascular endothelial growth factor; coupling; axonal outgrowth; guidance; angiogenesis; cerebral ischemia; neurogenesis; functional recovery; stroke

Increased microvessel density in the peri-infarct region has been reported and has been correlated with longer survival times in ischemic stroke patients and has improved outcomes in ischemic animal models.This raises the possibility that enhancement of angiogenesis is one of the strategies to facil...