Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease - Kunicki, Thomas J; Williams, Shirley A; Nugent, Diane J; Harrison, Paul; Segal, Helen C; Syed, Anila; Rothwell, Peter M (Thrombosis and haemostasis, 2009)
Keywords: Adenosine Diphosphate; Aged; Aged, 80 and over; Aspirin - therapeutic use; Cohort Studies; Cyclooxygenase 1 - genetics; Drug Resistance - genetics; England; Epinephrine; Female; Gene Frequency; Haplotypes; Humans; Integrin alpha2 - genetics; Integrin beta3 - genetics; Male; Membrane Glycoproteins; Membrane Proteins - genetics; Middle Aged; Platelet Aggregation - drug effects; Platelet Aggregation - genetics; Platelet Aggregation Inhibitors - therapeutic use; Platelet Count; Platelet Function Tests - instrumentation; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins - genetics; Polymorphism, Single Nucleotide; Receptors, Purinergic P2 - genetics; Treatment Failure; Up-Regulation; Vascular Diseases - blood; Vascular Diseases - drug therapy; Vascular Diseases - genetics; von Willebrand Factor - analysis; England