uORF-mediated translation allows engineered plant disease resistance without fitness costs

• Published in: Nature (London) Vol. 545; no. 7655; pp. 491 - 494
• Main Authors: Xu, Guoyong, Yuan, Meng, Ai, Chaoren, Liu, Lijing, Zhuang, Edward, Karapetyan, Sargis, Wang, Shiping, Dong, Xinnian
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 25.05.2017; Nature Publishing Group
• Subjects: 631/449/2169; 631/449/447/2311; 631/61/447/2311; Arabidopsis - genetics; Arabidopsis - immunology; Arabidopsis Proteins - biosynthesis; Arabidopsis Proteins - genetics; Crops, Agricultural - genetics; Crops, Agricultural - immunology; Disease resistance (Plants); DNA-Binding Proteins - biosynthesis; DNA-Binding Proteins - genetics; DNA-Binding Proteins - immunology; Gene Expression Regulation, Plant; Genetic aspects; Genetic engineering; Genetic Fitness - genetics; Health aspects; Heat Shock Transcription Factors; Heat-Shock Proteins - biosynthesis; Heat-Shock Proteins - genetics; Heat-Shock Proteins - immunology; Humanities and Social Sciences; letter; Methods; multidisciplinary; Open Reading Frames - genetics; Oryza - genetics; Oryza - immunology; Plant Diseases - genetics; Plant Diseases - immunology; Plant Immunity - genetics; Plant Proteins - biosynthesis; Plant Proteins - genetics; Plant Proteins - immunology; Promoter Regions, Genetic - genetics; Protein Biosynthesis; Science; Transcription Factors - biosynthesis; Transcription Factors - genetics; Transcription Factors - immunology; Transcription, Genetic; Translation (Genetics)

WebIn both laboratory and field studies, engineering translational control of immune mediator production in Arabidopsis and rice confers disease resistance, without compromising plant fitness. Programming plant immunity It is well established that plants elicit immune responses by reprogramming thei...