Multi-site voxel-based morphometry — Not quite there yet

• Published in: NeuroImage (Orlando, Fla.) Vol. 56; no. 3; pp. 1164 - 1170
• Main Authors: Focke, N.K., Helms, G., Kaspar, S., Diederich, C., Tóth, V., Dechent, P., Mohr, A., Paulus, W.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2011; Elsevier Limited
• Subjects: Algorithms; Bias; Brain Mapping - methods; Engineering and Technology; Humans; Image Processing, Computer-Assisted - methods; Linear Models; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - methods; Magnetic Resonance Imaging - statistics & numerical data; Medical Engineering; Medical Image Processing; Medical Imaging; Medicinsk bildbehandling; Medicinsk bildvetenskap; Medicinteknik; Multi-site; Regression Analysis; Reproducibility of Results; Scanners; Segmentation accuracy; Software; Studies; Teknik; Validation; Voxel-based morphometry; Validation; Segmentation accuracy; Bias; Voxel-based morphometry; Multi-site

Voxel-based morphometry (VBM) is a widely applied method in computational neurosciences but it is currently recommended to compare only data collected at a single MRI scanner. Multi-site VBM would be a desirable approach to increase group size and, thus, statistical power. We aimed to assess if mult...