The multimodal connectivity of the hippocampal complex in auditory and visual hallucinations

• Published in: Molecular psychiatry Vol. 19; no. 2; pp. 184 - 191
• Main Authors: Amad, A, Cachia, A, Gorwood, P, Pins, D, Delmaire, C, Rolland, B, Mondino, M, Thomas, P, Jardri, R
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.02.2014; Nature Publishing Group
• Subjects: 692/1807/1693; 692/699/476/1799; Adult; Adult and adolescent clinical studies; Antipsychotic Agents; Antipsychotic Agents - therapeutic use; Auditory Perception; Behavioral Sciences; Biological and medical sciences; Biological Psychology; Brain; Brain - pathology; Brain - physiopathology; Brain Mapping; Brain research; Caudate Nucleus; Caudate Nucleus - pathology; Caudate Nucleus - physiopathology; Diffusion Magnetic Resonance Imaging; Female; Functional magnetic resonance imaging; Hallucinations; Hallucinations - drug therapy; Hallucinations - etiology; Hallucinations - pathology; Hallucinations - physiopathology; Hallucinations and illusions; Hearing; Hippocampus; Hippocampus (Brain); Hippocampus - pathology; Hippocampus - physiopathology; Humans; Hypertrophy; Hypotheses; Life Sciences; Magnetic Resonance Imaging; Male; Medical sciences; Medicine; Medicine & Public Health; Mental disorders; Nerve Fibers, Myelinated; Nerve Fibers, Myelinated - pathology; Nerve Fibers, Myelinated - physiology; Neural networks; Neural Pathways; Neural Pathways - pathology; Neural Pathways - physiopathology; Neuroimaging; Neurosciences; original-article; Pharmacotherapy; Physiological aspects; Plasticity; Prefrontal Cortex; Prefrontal Cortex - pathology; Prefrontal Cortex - physiopathology; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Psychosis; Rest; Rest - physiology; Schizophrenia; Schizophrenia - complications; Schizophrenia - drug therapy; Schizophrenia - pathology; Schizophrenia - physiopathology; Sensory integration; Somatosensory cortex; Statistical analysis; Substantia alba; Testing; Thalamus; Thalamus - pathology; Thalamus - physiopathology; Visual Pathways; Visual Pathways - pathology; Visual Pathways - physiopathology; Visual Perception; France; Paris France; visual; schizophrenia; hippocampus; MRI; hallucinations; neuroplasticity; Central nervous system; Schizophrenia; Auditory hallucination; Nuclear magnetic resonance imaging; Visual hallucination; Encephalon; Psychosis; Brain plasticity; Vision; Medical imagery; Perception; Hippocampus

Hallucinations constitute one of the most representative and disabling symptoms of schizophrenia. Several Magnetic Resonance Imaging (MRI) findings support the hypothesis that distinct patterns of connectivity, particularly within networks involving the hippocampal complex (HC), could be associated...