Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice - Seshadri, Nivedita; Jonasson, Michael E.; Hunt, Kristin L.; Xiang, Bo; Cooper, Steven; Wheeler, Michael B.; Dolinsky, Vernon W.; Doucette, Christine A. (Molecular metabolism (Germany), 2017)
Keywords: Brief Communication; Glucose tolerance; Glucose-stimulated insulin secretion; Pancreatic islets; Uncoupling protein 2; β cells; MIN6; β cells; T2D; i.p.GTT; Glucose tolerance; Uncoupling protein 2; UCP2; GSIS; Ucp2-βKO; Glucose-stimulated insulin secretion; Pancreatic islets; ZT; Ins2-cre; LG; WT; HG; ZT, Zeitgeber time; GSIS, Glucose-stimulated insulin secretion; WT, wild type; LG, Low glucose; HG, High glucose; Ins2-cre, Ins2 promoter-driven cre recombinase; MIN6, Mouse insulinoma 6; T2D, Type 2 diabetes; i.p.GTT, intraperitoneal glucose tolerance test; UCP2, Uncoupling protein 2; Ucp2-βKO, β cell-specific Ucp2 knockout