Decoding Depression Severity From Intracranial Neural Activity

• Published in: Biological psychiatry (1969) Vol. 94; no. 6; pp. 445 - 453
• Main Authors: Xiao, Jiayang, Provenza, Nicole R., Asfouri, Joseph, Myers, John, Mathura, Raissa K., Metzger, Brian, Adkinson, Joshua A., Allawala, Anusha B., Pirtle, Victoria, Oswalt, Denise, Shofty, Ben, Robinson, Meghan E., Mathew, Sanjay J., Goodman, Wayne K., Pouratian, Nader, Schrater, Paul R., Patel, Ankit B., Tolias, Andreas S., Bijanki, Kelly R., Pitkow, Xaq, Sheth, Sameer A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.09.2023
• Subjects: Anterior cingulate cortex; Biomarker; Brain - physiology; Brain Mapping - methods; Decoding; Depression; Gyrus Cinguli; Humans; Intracranial recording; Prefrontal Cortex; Psychiatric/Mental Health; Spatiospectral features; Intracranial recording; Spatiospectral features; Depression; Biomarker; Decoding; Anterior cingulate cortex

Disorders of mood and cognition are prevalent, disabling, and notoriously difficult to treat. Fueling this challenge in treatment is a significant gap in our understanding of their neurophysiological basis. We recorded high-density neural activity from intracranial electrodes implanted in depression...