Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Sotagliflozin After Multiple Ascending Doses in Chinese Healthy Subjects - He, Xuemei; Gao, Xin; Xie, Panpan; Liu, Yuan; Bai, Wenjing; Liu, Yue; Shi, Aixin (Drug Design, Development and Therapy, 2022)
Keywords: Accumulation; Adult; Blood Glucose; Blood pressure; Body mass index; China; chinese healthy subjects; Chronic illnesses; Complications; Complications and side effects; Creatinine; Dextrose; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 1; Diabetes therapy; Diabetics; Drug Design, Development and Therapy; Electrocardiography; Enzymes; Glucose; Glycosides; Healthy Volunteers; Heart failure; Humans; Hypoglycemia; Insulin; Kidney diseases; Laboratories; lx4211; Metabolism; Metabolites; Mortality; Na+/glucose cotransporter; Original Research; Parameters; Pharmacodynamics; Pharmacokinetics; Pharmacology; Placebos; Plasma; Population; RM1-950; Safety; sotaglifozin; Therapeutics. Pharmacology; Type 2 diabetes; China; Beijing China; United States--US