Cost-effectiveness of pharmacogenetic testing to tailor smoking-cessation treatment

We evaluated the cost-effectiveness of a range of smoking cessation drug treatments, including varenicline, transdermal nicotine (TN), bupropion and the use of a genetic test to choose between TN and bupropion. We performed Monte Carlo simulation with sensitivity analysis, informing analyses with pu...

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Published in	The pharmacogenomics journal Vol. 8; no. 6; pp. 391 - 399
Main Authors	Heitjan, D F, Asch, D A, Ray, Riju, Rukstalis, Margaret, Patterson, Freda, Lerman, C
Format	Journal Article
Language	English
Published	London Nature Publishing Group UK 01.12.2008 Nature Publishing Group
Subjects	Benzazepines - administration & dosage Benzazepines - pharmacology Biomedical and Life Sciences Biomedicine Bupropion Bupropion - administration & dosage Bupropion - pharmacology Care and treatment Cigarette smoking Cost analysis Cost-Benefit Analysis Drug addiction Economic aspects Gene Expression Genetic aspects Genetic screening Genotype Human Genetics Humans Monte Carlo simulation Nicotine Oncology original-article Pharmacogenetics Pharmacotherapy Psychopharmacology Quinoxalines - administration & dosage Quinoxalines - pharmacology Receptors, Nicotinic - drug effects Sensitivity analysis Smokers Smoking Smoking Cessation - economics Smoking cessation products Varenicline United States tobacco dependence genetic testing Monte Carlo simulation addiction
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Abstract	We evaluated the cost-effectiveness of a range of smoking cessation drug treatments, including varenicline, transdermal nicotine (TN), bupropion and the use of a genetic test to choose between TN and bupropion. We performed Monte Carlo simulation with sensitivity analysis, informing analyses with published estimates of model parameters and current prices for genetic testing and smoking-cessation therapy. The primary outcomes were discounted life-years (LY) and lifetime tobacco-cessation treatment costs. In the base case, varenicline treatment was optimal with an ICER, compared to bupropion, of $2985/LY saved. In sensitivity analyses, varenicline was in all cases (and bupropion in most cases) admissible; only under favorable assumptions was the genetically tailored approach competitive. Our data suggest that an untailored approach of treatment with either bupropion or varenicline is a cost-effective form of tobacco dependence treatment, but a tailored approach for selecting between TN and bupropion can be cost-effective under plausible assumptions.
AbstractList	We evaluated the cost-effectiveness of a range of smoking cessation drug treatments, including varenicline, transdermal nicotine (TN), bupropion and the use of a genetic test to choose between TN and bupropion. We performed Monte Carlo simulation with sensitivity analysis, informing analyses with published estimates of model parameters and current prices for genetic testing and smoking-cessation therapy. The primary outcomes were discounted life-years (LY) and lifetime tobacco-cessation treatment costs. In the base case, varenicline treatment was optimal with an ICER, compared to bupropion, of $2985/LY saved. In sensitivity analyses, varenicline was in all cases (and bupropion in most cases) admissible; only under favorable assumptions was the genetically tailored approach competitive. Our data suggest that an untailored approach of treatment with either bupropion or varenicline is a cost-effective form of tobacco dependence treatment, but a tailored approach for selecting between TN and bupropion can be cost-effective under plausible assumptions.
Audience	Academic
Author	Asch, D A Lerman, C Rukstalis, Margaret Patterson, Freda Heitjan, D F Ray, Riju
AuthorAffiliation	5 The Transdisciplinary Tobacco Use Research Center, University of Pennsylvania, Philadelphia, PA, USA 1 Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA 4 The Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA 6 Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA 2 The Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA 3 Center for Health Equity Research and Promotion, Philadelphia Veterans Administration Medical Center, Philadelphia, PA, USA 7 Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, USA
AuthorAffiliation_xml	– name: 4 The Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA – name: 2 The Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA – name: 6 Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA – name: 7 Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, USA – name: 1 Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA – name: 5 The Transdisciplinary Tobacco Use Research Center, University of Pennsylvania, Philadelphia, PA, USA – name: 3 Center for Health Equity Research and Promotion, Philadelphia Veterans Administration Medical Center, Philadelphia, PA, USA
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Cites_doi	10.1016/j.biopsych.2006.10.005 10.1073/pnas.0500329102 10.1038/sj.mp.4001794 10.1016/S0025-6196(11)63361-2 10.1176/appi.ajp.158.5.802 10.1016/j.amepre.2006.06.021 10.1080/14622200410001734058 10.1016/S0149-2918(01)80023-0 10.1208/aapsj080121 10.1080/14622200412331320761 10.1111/j.1742-1241.2006.01077.x 10.1016/S0893-133X(02)00293-2 10.1176/appi.ajp.160.4.677 10.1136/bmj.38142.554479.AE 10.1001/archpsyc.64.2.218 10.1176/appi.ajp.161.11.2100 10.1136/jme.2004.007229 10.3310/hta6160 10.1001/archinte.166.15.1561 10.2165/00019053-200422080-00001 10.1038/sj.npp.1300861 10.1007/s00228-003-0610-6 10.1038/sj.mp.4001494 10.1111/j.1360-0443.2006.01534.x 10.1093/aje/kwf150 10.1006/pmed.1996.0127 10.7326/0003-4819-145-10-200611210-00007 10.1097/00008571-200406000-00002 10.1037/0022-006X.74.2.286 10.1038/sj.mp.4001502 10.1136/tc.6.suppl_2.S57 10.1080/14622200410001676396 10.1111/j.1360-0443.2004.00540.x 10.1001/jama.296.20.2480 10.1001/jama.296.1.47 10.1136/jech.55.5.334 10.1016/S0140-6736(99)90001-6 10.1517/14622416.6.3.211 10.1136/tc.2005.015487 10.1016/j.clpt.2006.02.006 10.7326/0003-4819-140-6-200403160-00009 10.1053/euhj.2000.2151 10.1038/sj.npp.1300219 10.1001/jama.1996.03530400035035 10.1517/14728214.11.3.429 10.1016/S0002-9149(00)01487-9 10.1056/NEJM199710093371506 10.1177/027298902237708 10.1056/NEJM199809033391006 10.1038/sj.tpj.6500238 10.1186/1471-2458-6-300 10.1001/jama.1990.03440200064024 10.1093/oso/9780195108248.001.0001
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References	Oslin, DW, Berrettini, W, Kranzler, HR, Pettinati, H, Gelernter, J, Volpicelli, JR 2003; 28 Lerman, C, Jepson, C, Wileyto, EP, Epstein, LH, Rukstalis, M, Patterson, F 2006; 31 Qiao, Q, Tervahauta, M, Nissinen, A, Tuomilehto, J 2000; 21 Lee, AM, Jepson, C, Hoffmann, E, Epstein, L, Hawk, LW, Lerman, C 2007; 62 Nides, M, Oncken, C, Gonzales, D, Rennard, S, Watsky, EJ, Anziano, R 2006; 166 2002; 51 Hughes, DA, Vilar, FJ, Ward, CC, Alfirevic, A, Park, BK, Pirmohamed, M 2004; 14 Carlsten, C, Burke, W 2006; 296 Kirchheiner, J, Nickchen, K, Bauer, M, Wong, ML, Licinio, J, Roots, I 2004; 9 Schafer, M, Rujescu, D, Giegling, I, Guntermann, A, Erfurth, A, Bondy, B 2001; 158 Hughes, J, Stead, L, Lancaster, T 2007; 1 Partin, MR, An, LC, Nelson, DB, Nugent, S, Snyder, A, Fu, SS 2006; 31 Wu, P, Wilson, K, Dimoulas, P, Mills, EJ 2006; 6 Reynolds, GP, Zhang, Z, Zhang, X 2003; 160 Han, ES, Foulds, J, Steinberg, B, Gandhi, KK, West, B, Richardson, DL 2006; 60 Gotfredsen, NS, Holst, C, Prescott, E, Vestbo, J, Osler, M 2002; 156 Stapleton, JA, Lowin, A, Russell, MA 1999; 354 Song, F, Raftery, J, Aveyard, P, Hyde, C, Barton, P, Woolacott, N 2002; 22S5 Munafò, MR, Shields, AE, Berrettini, WH, Patterson, F, Lerman, C 2005; 6 Lerman, C, Wileyto, EP, Patterson, F, Rukstalis, M, Audrain-McGovern, J, Restine, S 2004; 4 1990 Lerman, C, Tyndale, R, Patterson, F, Wileyto, EP, Shields, PG, Pinto, A 2006; 79 Lerer, B, Segman, RH, Fangerau, H, Daly, AK, Basile, VS, Cavallaro, R 2002; 27 2000 Hughes, JR, Keely, J, Naud, S 2004; 99 Shields, A, Lerman, C, Sullivan, P 2004; 6 Woolacott, NF, Jones, L, Forbes, CA, Mather, LC, Sowden, AJ, Song, FJ 2002; 6 Gonzales, D, Rennard, SI, Nides, M, Oncken, C, Azoulay, S, Billing, CB 2006; 296 Fiscella, K, Franks, P 1996; 275 Fiore, MC, Novotny, TE, Pierce, JP, Giovino, GA, Hatzaiandreu, EJ, Newcomb, PA 1990; 263 Killen, JD, Fortmann, SP, Murphy, GM, Hayward, C, Arredondo, C, Cromp, D 2006; 74 Jamerson, BD, Nides, M, Jorensby, DE, Donahue, R, Garrett, P, Johnston, JA 2001; 23 Lerman, C, Kaufmann, V, Rukstalis, M, Patterson, F, Perkins, K, Audrain-McGovern, J 2004; 140 Flowers, CR, Veenstra, D 2004; 22 Hymowitz, N, Cummings, KM, Hyland, A, Lynn, WR, Pechacek, TF, Hartwell, TDK 1997; 6 Etter, JF, Stapleton, JA 2006; 15 Arias, E 2004; 53 Malaiyandi, V, Lerman, C, Benowitz, NL, Jepson, C, Patterson, F, Tyndale, RF 2006; 11 Barendregt, JJ, Bonneux, L, van der Maas, PJ 1997; 337 Peters, EJ, Slager, SL, McGrath, PJ, Knowles, JA, Hamilton, SP 2004; 9 Hyland, A, Li, Q, Bauer, JE, Giovino, GA, Steger, C 2004; 6S3 Liu, QR, Drgon, T, Walther, D, Johnson, C, Poleskaya, O, Hess, J 2005; 102 2005 Cinciripini, P, Wetter, D, Tomlinson, G, Tsoh, J, De Moor, C, Cinciripini, L 2004; 6 2002 Croghan, IT, Offord, KP, Evans, RW, Schmidt, S, Gomez-Dahl, LC, Schroeder, DR 1997; 72 Rutter, JL 2006; 8 Cornuz, J, Pinget, C, Gilbert, A, Paccaud, F 2003; 59 Corrigan, OP 2005; 31 Schnoll, RA, Lerman, C 2006; 11 Wasley, MA, McNagny, SE, Phillips, VL, Ahluwalia, JS 1997; 26 Roden, DM, Altman, RB, Benowitz, NL, Flockhart, DA, Giacomini, KM, Johnson, JA 2006; 145 Foody, JM, Cole, CR, Blackstone, EH, Lauer, MS 2001; 87 West, R, Gilsenan, A, Coste, F, Zhou, X, Brouard, R, Nonnemaker, J 2006; 101 Doll, R, Peto, R, Boreham, J, Sutherland, I 2004; 328 Esson, KM, Leeder, SR 2004 Gold, MR, Siegel, JE, Russell, LB, Weinstein, MC 1996 Curry, SJ, Grothaus, LC, McAfee, T, Pabiniak, C 1998; 339 Hall, SM, Humfleet, GL, Reus, VI, Muñoz, RF, Cullen, J 2004; 161 McCarron, P, Davey Smith, G, Okasha, M, McEwen, J 2001; 55 Polanczyk, G, Zeni, C, Genro, JP, Guimaraes, AP, Roman, T, Hutz, MH 2007; 64 Jamerson, Nides, Jorensby, Donahue, Garrett, Johnston (CR43) 2001; 23 Liu, Drgon, Walther, Johnson, Poleskaya, Hess (CR48) 2005; 102 Malaiyandi, Lerman, Benowitz, Jepson, Patterson, Tyndale (CR26) 2006; 11 Hughes, Stead, Lancaster (CR16) 2007; 1 Hall, Humfleet, Reus, Muñoz, Cullen (CR44) 2004; 161 Curry, Grothaus, McAfee, Pabiniak (CR33) 1998; 339 Hymowitz, Cummings, Hyland, Lynn, Pechacek, Hartwell (CR39) 1997; 6 McCarron, Davey Smith, Okasha, McEwen (CR58) 2001; 55 Cinciripini, Wetter, Tomlinson, Tsoh, De Moor, Cinciripini (CR47) 2004; 6 Lerman, Kaufmann, Rukstalis, Patterson, Perkins, Audrain-McGovern (CR51) 2004; 140 Polanczyk, Zeni, Genro, Guimaraes, Roman, Hutz (CR5) 2007; 64 Qiao, Tervahauta, Nissinen, Tuomilehto (CR59) 2000; 21 Hughes, Vilar, Ward, Alfirevic, Park, Pirmohamed (CR27) 2004; 14 Wasley, McNagny, Phillips, Ahluwalia (CR31) 1997; 26 Barendregt, Bonneux, van der Maas (CR49) 1997; 337 Croghan, Offord, Evans, Schmidt, Gomez-Dahl, Schroeder (CR32) 1997; 72 Kirchheiner, Nickchen, Bauer, Wong, Licinio, Roots (CR2) 2004; 9 Foody, Cole, Blackstone, Lauer (CR56) 2001; 87 Fiore, Novotny, Pierce, Giovino, Hatzaiandreu, Newcomb (CR52) 1990; 263 Schnoll, Lerman (CR21) 2006; 11 Woolacott, Jones, Forbes, Mather, Sowden, Song (CR35) 2002; 6 Hughes, Keely, Naud (CR53) 2004; 99 Cornuz, Pinget, Gilbert, Paccaud (CR37) 2003; 59 Killen, Fortmann, Murphy, Hayward, Arredondo, Cromp (CR42) 2006; 74 Corrigan (CR10) 2005; 31 Lerer, Segman, Fangerau, Daly, Basile, Cavallaro (CR8) 2002; 27 Roden, Altman, Benowitz, Flockhart, Giacomini, Johnson (CR29) 2006; 145 Lerman, Jepson, Wileyto, Epstein, Rukstalis, Patterson (CR7) 2006; 31 (CR38) 2002; 51 Arias (CR54) 2004; 53 Han, Foulds, Steinberg, Gandhi, West, Richardson (CR45) 2006; 60 Song, Raftery, Aveyard, Hyde, Barton, Woolacott (CR36) 2002; 22S5 Carlsten, Burke (CR50) 2006; 296 Doll, Peto, Boreham, Sutherland (CR55) 2004; 328 Hyland, Li, Bauer, Giovino, Steger (CR41) 2004; 6S3 CR14 CR13 CR12 Etter, Stapleton (CR17) 2006; 15 Fiscella, Franks (CR30) 1996; 275 Stapleton, Lowin, Russell (CR34) 1999; 354 Nides, Oncken, Gonzales, Rennard, Watsky, Anziano (CR19) 2006; 166 Partin, An, Nelson, Nugent, Snyder, Fu (CR46) 2006; 31 Schafer, Rujescu, Giegling, Guntermann, Erfurth, Bondy (CR3) 2001; 158 Gotfredsen, Holst, Prescott, Vestbo, Osler (CR57) 2002; 156 Shields, Lerman, Sullivan (CR11) 2004; 6 Peters, Slager, McGrath, Knowles, Hamilton (CR4) 2004; 9 Lerman, Wileyto, Patterson, Rukstalis, Audrain-McGovern, Restine (CR23) 2004; 4 Wu, Wilson, Dimoulas, Mills (CR18) 2006; 6 Oslin, Berrettini, Kranzler, Pettinati, Gelernter, Volpicelli (CR6) 2003; 28 Reynolds, Zhang, Zhang (CR9) 2003; 160 Lee, Jepson, Hoffmann, Epstein, Hawk, Lerman (CR24) 2007; 62 West, Gilsenan, Coste, Zhou, Brouard, Nonnemaker (CR40) 2006; 101 Rutter (CR22) 2006; 8 Flowers, Veenstra (CR28) 2004; 22 CR60 Gold, Siegel, Russell, Weinstein (CR61) 1996 Esson, Leeder (CR15) 2004 Munafò, Shields, Berrettini, Patterson, Lerman (CR1) 2005; 6 Gonzales, Rennard, Nides, Oncken, Azoulay, Billing (CR20) 2006; 296 Lerman, Tyndale, Patterson, Wileyto, Shields, Pinto (CR25) 2006; 79 15370164 - Nicotine Tob Res. 2004 Aug;6(4):675-88 16939383 - Expert Opin Emerg Drugs. 2006 Sep;11(3):429-44 16939548 - Int J Clin Pract. 2006 Sep;60(9):1068-74 15023708 - Ann Intern Med. 2004 Mar 16;140(6):426-33 9321534 - N Engl J Med. 1997 Oct 9;337(15):1052-7 16649873 - J Consult Clin Psychol. 2006 Apr;74(2):286-94 11394732 - Clin Ther. 2001 May;23(5):744-52 16765148 - Clin Pharmacol Ther. 2006 Jun;79(6):600-8 10421303 - Lancet. 1999 Jul 17;354(9174):210-5 16123753 - Neuropsychopharmacology. 2006 Jan;31(1):231-42 9725926 - N Engl J Med. 1998 Sep 3;339(10):673-9 16979453 - Am J Prev Med. 2006 Oct;31(4):293-9 15203796 - Nicotine Tob Res. 2004 Apr;6(2):229-39 12186222 - MMWR Morb Mortal Wkly Rep. 2002 Jul 26;51(29):642-5 16911736 - Addiction. 2006 Sep;101(9):1352-61 12668355 - Am J Psychiatry. 2003 Apr;160(4):677-9 16013953 - Pharmacogenomics. 2005 Apr;6(3):211-23 16885576 - Tob Control. 2006 Aug;15(4):280-5 16584126 - AAPS J. 2006 Mar 24;8(1):E174-84 15738433 - J Med Ethics. 2005 Mar;31(3):144-8 9583654 - Tob Control. 1997;6 Suppl 2:S57-62 15052272 - Mol Psychiatry. 2004 Sep;9(9):879-89 17223085 - Biol Psychiatry. 2007 Sep 15;62(6):635-41 11329406 - Am J Psychiatry. 2001 May;158(5):802-4 9085397 - Prev Med. 1997 Mar-Apr;26(2):264-70 14678060 - Addiction. 2004 Jan;99(1):29-38 17283289 - Arch Gen Psychiatry. 2007 Feb;64(2):218-24 8601956 - JAMA. 1996 Apr 24;275(16):1247-51 16908788 - Arch Intern Med. 2006 Aug 14-28;166(15):1561-8 11249887 - Am J Cardiol. 2001 Mar 15;87(6):706-11 17253443 - Cochrane Database Syst Rev. 2007 Jan 24;(1):CD000031 12446255 - Am J Epidemiol. 2002 Dec 1;156(11):994-1001 16091475 - Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11864-9 15514412 - Am J Psychiatry. 2004 Nov;161(11):2100-7 12369228 - Med Decis Making. 2002 Sep-Oct;22(5 Suppl):S26-37 11297653 - J Epidemiol Community Health. 2001 May;55(5):334-5 17156479 - BMC Public Health. 2006 Dec 11;6:300 16820546 - JAMA. 2006 Jul 5;296(1):47-55 15799599 - Nicotine Tob Res. 2004 Dec;6 Suppl 3:S363-9 15037866 - Mol Psychiatry. 2004 May;9(5):442-73 12759795 - Eur J Clin Pharmacol. 2003 Jul;59(3):201-6 15580947 - Natl Vital Stat Rep. 2004 Nov 10;53(6):1-38 12269277 - Health Technol Assess. 2002;6(16):1-245 10988015 - Eur Heart J. 2000 Oct;21(19):1621-6 12062911 - Neuropsychopharmacology. 2002 Jul;27(1):105-19 15213107 - BMJ. 2004 Jun 26;328(7455):1519 17119145 - JAMA. 2006 Nov 22;296(20):2480-2 15217305 - Pharmacoeconomics. 2004;22(8):481-93 15007373 - Pharmacogenomics J. 2004;4(3):184-92 17116919 - Ann Intern Med. 2006 Nov 21;145(10):749-57 2271019 - JAMA. 1990 May 23-30;263(20):2760-5 16402128 - Mol Psychiatry. 2006 Apr;11(4):400-9 12813472 - Neuropsychopharmacology. 2003 Aug;28(8):1546-52 9379693 - Mayo Clin Proc. 1997 Oct;72(10):917-24 15247625 - Pharmacogenetics. 2004 Jun;14(6):335-42 M Nides (BF6500492_CR19) 2006; 166 QR Liu (BF6500492_CR48) 2005; 102 R West (BF6500492_CR40) 2006; 101 A Hyland (BF6500492_CR41) 2004; 6S3 JD Killen (BF6500492_CR42) 2006; 74 MR Munafò (BF6500492_CR1) 2005; 6 R Doll (BF6500492_CR55) 2004; 328 C Lerman (BF6500492_CR7) 2006; 31 JA Stapleton (BF6500492_CR34) 1999; 354 DM Roden (BF6500492_CR29) 2006; 145 K Fiscella (BF6500492_CR30) 1996; 275 OP Corrigan (BF6500492_CR10) 2005; 31 JF Etter (BF6500492_CR17) 2006; 15 JM Foody (BF6500492_CR56) 2001; 87 P McCarron (BF6500492_CR58) 2001; 55 A Shields (BF6500492_CR11) 2004; 6 KM Esson (BF6500492_CR15) 2004 N Hymowitz (BF6500492_CR39) 1997; 6 D Gonzales (BF6500492_CR20) 2006; 296 IT Croghan (BF6500492_CR32) 1997; 72 C Lerman (BF6500492_CR25) 2006; 79 J Kirchheiner (BF6500492_CR2) 2004; 9 DW Oslin (BF6500492_CR6) 2003; 28 DA Hughes (BF6500492_CR27) 2004; 14 BD Jamerson (BF6500492_CR43) 2001; 23 C Carlsten (BF6500492_CR50) 2006; 296 MR Partin (BF6500492_CR46) 2006; 31 G Polanczyk (BF6500492_CR5) 2007; 64 CR Flowers (BF6500492_CR28) 2004; 22 F Song (BF6500492_CR36) 2002; 22S5 C Lerman (BF6500492_CR23) 2004; 4 P Cinciripini (BF6500492_CR47) 2004; 6 MC Fiore (BF6500492_CR52) 1990; 263 C Lerman (BF6500492_CR51) 2004; 140 JJ Barendregt (BF6500492_CR49) 1997; 337 BF6500492_CR60 P Wu (BF6500492_CR18) 2006; 6 E Arias (BF6500492_CR54) 2004; 53 SJ Curry (BF6500492_CR33) 1998; 339 NS Gotfredsen (BF6500492_CR57) 2002; 156 JL Rutter (BF6500492_CR22) 2006; 8 B Lerer (BF6500492_CR8) 2002; 27 Q Qiao (BF6500492_CR59) 2000; 21 J Hughes (BF6500492_CR16) 2007; 1 MR Gold (BF6500492_CR61) 1996 BF6500492_CR13 BF6500492_CR14 V Malaiyandi (BF6500492_CR26) 2006; 11 BF6500492_CR12 Centers for Disease Control and Prevention (BF6500492_CR38) 2002; 51 AM Lee (BF6500492_CR24) 2007; 62 JR Hughes (BF6500492_CR53) 2004; 99 ES Han (BF6500492_CR45) 2006; 60 MA Wasley (BF6500492_CR31) 1997; 26 M Schafer (BF6500492_CR3) 2001; 158 EJ Peters (BF6500492_CR4) 2004; 9 SM Hall (BF6500492_CR44) 2004; 161 NF Woolacott (BF6500492_CR35) 2002; 6 J Cornuz (BF6500492_CR37) 2003; 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References_xml	– year: 2005 publication-title: Center for Medicare & Medicaid Manual System, Transmittal 562 – volume: 337 start-page: 1052 year: 1997 end-page: 1057 article-title: The health care costs of smoking publication-title: N Engl J Med contributor: fullname: van der Maas, PJ – volume: 9 start-page: 442 year: 2004 end-page: 473 article-title: Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response publication-title: Mol Psychiatry contributor: fullname: Roots, I – volume: 11 start-page: 429 year: 2006 end-page: 444 article-title: Current and emerging pharmacotherapies for treating tobacco dependence publication-title: Expert Opin Emerg Drugs contributor: fullname: Lerman, C – volume: 6 start-page: S57 year: 1997 end-page: S62 article-title: Predictors of smoking cessation in a cohort of adult smokers followed for five years publication-title: Tob Control contributor: fullname: Hartwell, TDK – volume: 156 start-page: 994 year: 2002 end-page: 1001 article-title: Smoking reduction, smoking cessation, and mortality: a 16-year follow-up of 19, 732 men and women from the Copenhagen centre for prospective population studies publication-title: Am J Epidemiol contributor: fullname: Osler, M – volume: 62 start-page: 635 year: 2007 end-page: 641 article-title: CYP2B6 genotype alters abstinence rates in a bupropion smoking cessation trial publication-title: Biol Psychiatry contributor: fullname: Lerman, C – year: 1990 publication-title: The Health Benefits of Smoking Cessation – volume: 6S3 start-page: S363 year: 2004 end-page: S369 article-title: Predictors of cessation in a cohort of current and former smokers followed over 13 years publication-title: Nicotine Tob Res contributor: fullname: Steger, C – volume: 1 start-page: CD000031 year: 2007 article-title: Antidepressants for smoking cessation publication-title: Cochrane Database Syst Rev contributor: fullname: Lancaster, T – volume: 64 start-page: 218 year: 2007 end-page: 224 article-title: Association of the adrenergic alpha2A receptor gene with methylphenidate improvement of inattentive symptoms in children and adolescents with attention-deficit hyperactivity disorder publication-title: Arch Gen Psychiatry contributor: fullname: Hutz, MH – volume: 22 start-page: 481 year: 2004 end-page: 493 article-title: The role of cost-effectiveness analysis in the era of pharmacogenomics publication-title: Pharmacoeconomics contributor: fullname: Veenstra, D – volume: 263 start-page: 2760 year: 1990 end-page: 2765 article-title: Methods used to quit smoking in the United States. Do cessation programs help? publication-title: JAMA contributor: fullname: Newcomb, PA – volume: 145 start-page: 749 year: 2006 end-page: 757 article-title: Pharmacogenomics: challenges and opportunities publication-title: Ann Intern Med contributor: fullname: Johnson, JA – volume: 8 start-page: E174 year: 2006 end-page: E184 article-title: Symbiotic relationship of pharmacogenetics and drugs of abuse publication-title: AAPS J contributor: fullname: Rutter, JL – volume: 166 start-page: 1561 year: 2006 end-page: 1568 article-title: Smoking cessation with varenicline, a selective alpha4beta2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up publication-title: Arch Intern Med contributor: fullname: Anziano, R – volume: 55 start-page: 334 year: 2001 end-page: 335 article-title: Smoking in adolescence and young adulthood and mortality in later life: prospective observational study publication-title: J Epidemiol Community Health contributor: fullname: McEwen, J – volume: 28 start-page: 1546 year: 2003 end-page: 1552 article-title: A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients publication-title: Neuropsychopharmacology contributor: fullname: Volpicelli, JR – volume: 74 start-page: 286 year: 2006 end-page: 294 article-title: Extended treatment with bupropion SR for cigarette smoking cessation publication-title: J Consult Clin Psychol contributor: fullname: Cromp, D – volume: 53 start-page: 1 year: 2004 end-page: 38 article-title: United States life tables, 2002 publication-title: Nat Vital Stat Rep contributor: fullname: Arias, E – volume: 31 start-page: 293 year: 2006 end-page: 299 article-title: Randomized trial of an intervention to facilitate recycling for relapsed smokers publication-title: Am J Prev Med contributor: fullname: Fu, SS – volume: 6 start-page: 1 year: 2002 end-page: 245 article-title: The clinical effectiveness and cost-effectiveness of bupropion and nicotine replacement therapy for smoking cessation: a systematic review and economic evaluation publication-title: Health Technol Assess contributor: fullname: Song, FJ – year: 2004 publication-title: The Millennium Development Goals and Tobacco Control: An Opportunity for Global Partnership contributor: fullname: Leeder, SR – volume: 4 start-page: 184 year: 2004 end-page: 192 article-title: The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial publication-title: Pharmacogenomics J contributor: fullname: Restine, S – volume: 354 start-page: 210 year: 1999 end-page: 215 article-title: Prescription of transdermal nicotine patches for smoking cessation in general practice: evaluation of cost-effectiveness publication-title: Lancet contributor: fullname: Russell, MA – volume: 79 start-page: 600 year: 2006 end-page: 608 article-title: Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation publication-title: Clin Pharmacol Ther contributor: fullname: Pinto, A – volume: 102 start-page: 11864 year: 2005 end-page: 11869 article-title: Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples publication-title: Proc Natl Acad Sci USA contributor: fullname: Hess, J – volume: 99 start-page: 29 year: 2004 end-page: 38 article-title: Shape of the relapse curve and long-term abstinence among untreated smokers publication-title: Addiction contributor: fullname: Naud, S – volume: 31 start-page: 231 year: 2006 end-page: 242 article-title: Role of functional genetic variation in the dopamine D2 receptor (DRD2) in response to bupropion and nicotine replacement therapy for tobacco dependence: results of two randomized clinical trials publication-title: Neuropsychopharmacology contributor: fullname: Patterson, F – volume: 6 start-page: 229 year: 2004 end-page: 239 article-title: The effects of the DRD2 polymorphism on smoking cessation and negative affect: evidence for a pharmacogenetic effect on mood publication-title: Nicotine Tob Res contributor: fullname: Cinciripini, L – year: 2002 publication-title: Saving Lives, Saving Money: Why States Should Invest in a Tobacco-Free Future – volume: 22S5 start-page: S26 year: 2002 end-page: S37 article-title: Cost-effectiveness of pharmacological interventions for smoking cessation: a literature review and a decision analytic analysis publication-title: Med Decis Making contributor: fullname: Woolacott, N – volume: 60 start-page: 1068 year: 2006 end-page: 1074 article-title: Characteristics and smoking cessation outcomes of patients returning for repeat tobacco dependence treatment publication-title: Int J Clin Pract contributor: fullname: Richardson, DL – volume: 14 start-page: 335 year: 2004 end-page: 342 article-title: Cost-effectiveness analysis of HLA B 5701 genotyping in preventing abacavir hypersensitivity publication-title: Pharmacogenetics contributor: fullname: Pirmohamed, M – volume: 161 start-page: 2100 year: 2004 end-page: 2107 article-title: Extended nortriptyline and psychological treatment for cigarette smoking publication-title: Am J Psychiatry contributor: fullname: Cullen, J – volume: 27 start-page: 105 year: 2002 end-page: 119 article-title: Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism publication-title: Neuropsychopharmacology contributor: fullname: Cavallaro, R – volume: 31 start-page: 144 year: 2005 end-page: 148 article-title: Pharmacogenetics, ethical issues: review of the Nuffield Council on Bioethics Report publication-title: J Med Ethics contributor: fullname: Corrigan, OP – volume: 6 start-page: 300 year: 2006 article-title: Effectiveness of smoking cessation therapies: a systematic review and meta-analysis publication-title: BMC Public Health contributor: fullname: Mills, EJ – volume: 72 start-page: 917 year: 1997 end-page: 924 article-title: Cost-effectiveness of treating nicotine dependence: the Mayo Clinic experience publication-title: Mayo Clin Proc contributor: fullname: Schroeder, DR – volume: 296 start-page: 2480 year: 2006 end-page: 2482 article-title: Potential for genetics to promote public health: genetics research on smoking suggests caution about expectations publication-title: JAMA contributor: fullname: Burke, W – volume: 6 start-page: 211 year: 2005 end-page: 223 article-title: Pharmacogenetics and nicotine addiction treatment publication-title: Pharmacogenomics contributor: fullname: Lerman, C – volume: 51 start-page: 642 year: 2002 end-page: 645 article-title: Cigarette smoking among adults-United States 2000 publication-title: MMWR – year: 1996 publication-title: Cost-Effectiveness in Health and Medicine contributor: fullname: Weinstein, MC – volume: 26 start-page: 264 year: 1997 end-page: 270 article-title: The cost-effectiveness of the nicotine transdermal patch for smoking cessation publication-title: Prev Med contributor: fullname: Ahluwalia, JS – volume: 21 start-page: 1621 year: 2000 end-page: 1626 article-title: Mortality from all causes and from coronary heart disease related to smoking and changes in smoking during a 35-year follow-up of middle-aged Finnish men publication-title: Eur Heart J contributor: fullname: Tuomilehto, J – volume: 59 start-page: 201 year: 2003 end-page: 206 article-title: Cost-effectiveness analysis of the first-line therapies for nicotine dependence publication-title: Eur J Clin Pharmacol contributor: fullname: Paccaud, F – volume: 6 start-page: 675 year: 2004 end-page: 688 article-title: Translating emerging research on the genetics of smoking into clinical practice: ethical and social considerations publication-title: Nicotine Tob Res contributor: fullname: Sullivan, P – volume: 160 start-page: 677 year: 2003 end-page: 679 article-title: Polymorphism of the promoter region of the serotonin 5-HT(2C) receptor gene and clozapine-induced weight gain publication-title: Am J Psychiatry contributor: fullname: Zhang, X – volume: 328 start-page: 1519 year: 2004 end-page: 1527 article-title: Mortality in relation to smoking: 50 year's observations on male British doctors publication-title: BMJ contributor: fullname: Sutherland, I – volume: 275 start-page: 1247 year: 1996 end-page: 1251 article-title: Cost-effectiveness of the transdermal nicotine patch as an adjunct to physicians' smoking cessation counseling publication-title: JAMA contributor: fullname: Franks, P – volume: 158 start-page: 802 year: 2001 end-page: 804 article-title: Association of short-term response to haloperidol treatment with a polymorphism in the dopamine D(2) receptor gene publication-title: Am J Psychiatry contributor: fullname: Bondy, B – volume: 9 start-page: 879 year: 2004 end-page: 889 article-title: Investigation of serotonin-related genes in antidepressant response publication-title: Mol Psychiatry contributor: fullname: Hamilton, SP – volume: 140 start-page: 426 year: 2004 end-page: 433 article-title: Individualizing nicotine replacement therapy for the treatment of tobacco dependence: a randomized trial publication-title: Ann Intern Med contributor: fullname: Audrain-McGovern, J – volume: 101 start-page: 1352 year: 2006 end-page: 1361 article-title: The ATTEMPT cohort: a multi-national longitudinal study of predictors, patterns and consequences of smoking cessation; introduction and evaluation of internet recruitment and data collection methods [erratum appears in 2006 Oct;101:1528] publication-title: Addiction contributor: fullname: Nonnemaker, J – volume: 23 start-page: 744 year: 2001 end-page: 752 article-title: Late-term smoking cessation despite initial failure: an evaluation of bupropion sustained release, nicotine patch, combination therapy, and placebo publication-title: Clin Ther contributor: fullname: Johnston, JA – volume: 87 start-page: 706 year: 2001 end-page: 711 article-title: A propensity analysis of cigarette smoking and mortality with consideration of the effects of alcohol publication-title: Am J Cardiol contributor: fullname: Lauer, MS – volume: 11 start-page: 400 year: 2006 end-page: 409 article-title: Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy publication-title: Mol Psychiatry contributor: fullname: Tyndale, RF – volume: 296 start-page: 47 year: 2006 end-page: 55 article-title: Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial publication-title: JAMA contributor: fullname: Billing, CB – volume: 15 start-page: 280 year: 2006 end-page: 285 article-title: Nicotine replacement therapy for long-term smoking cessation: a meta-analysis publication-title: Tob Control contributor: fullname: Stapleton, JA – year: 2000 publication-title: Healthy People 2010 – volume: 339 start-page: 673 year: 1998 end-page: 679 article-title: Use and cost effectiveness of smoking-cessation services under four insurance plans in a health maintenance organization publication-title: N Engl J Med contributor: fullname: Pabiniak, C – volume: 62 start-page: 635 year: 2007 end-page: 641 ident: CR24 article-title: CYP2B6 genotype alters abstinence rates in a bupropion smoking cessation trial publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2006.10.005 contributor: fullname: Lerman – volume: 102 start-page: 11864 year: 2005 end-page: 11869 ident: CR48 article-title: Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0500329102 contributor: fullname: Hess – ident: CR12 – volume: 11 start-page: 400 year: 2006 end-page: 409 ident: CR26 article-title: Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001794 contributor: fullname: Tyndale – volume: 72 start-page: 917 year: 1997 end-page: 924 ident: CR32 article-title: Cost-effectiveness of treating nicotine dependence: the Mayo Clinic experience publication-title: Mayo Clin Proc doi: 10.1016/S0025-6196(11)63361-2 contributor: fullname: Schroeder – volume: 158 start-page: 802 year: 2001 end-page: 804 ident: CR3 article-title: Association of short-term response to haloperidol treatment with a polymorphism in the dopamine D(2) receptor gene publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.158.5.802 contributor: fullname: Bondy – volume: 31 start-page: 293 year: 2006 end-page: 299 ident: CR46 article-title: Randomized trial of an intervention to facilitate recycling for relapsed smokers publication-title: Am J Prev Med doi: 10.1016/j.amepre.2006.06.021 contributor: fullname: Fu – year: 1996 ident: CR61 publication-title: Cost-Effectiveness in Health and Medicine contributor: fullname: Weinstein – volume: 6 start-page: 675 year: 2004 end-page: 688 ident: CR11 article-title: Translating emerging research on the genetics of smoking into clinical practice: ethical and social considerations publication-title: Nicotine Tob Res doi: 10.1080/14622200410001734058 contributor: fullname: Sullivan – volume: 23 start-page: 744 year: 2001 end-page: 752 ident: CR43 article-title: Late-term smoking cessation despite initial failure: an evaluation of bupropion sustained release, nicotine patch, combination therapy, and placebo publication-title: Clin Ther doi: 10.1016/S0149-2918(01)80023-0 contributor: fullname: Johnston – volume: 8 start-page: E174 year: 2006 end-page: E184 ident: CR22 article-title: Symbiotic relationship of pharmacogenetics and drugs of abuse publication-title: AAPS J doi: 10.1208/aapsj080121 contributor: fullname: Rutter – volume: 6S3 start-page: S363 year: 2004 end-page: S369 ident: CR41 article-title: Predictors of cessation in a cohort of current and former smokers followed over 13 years publication-title: Nicotine Tob Res doi: 10.1080/14622200412331320761 contributor: fullname: Steger – volume: 60 start-page: 1068 year: 2006 end-page: 1074 ident: CR45 article-title: Characteristics and smoking cessation outcomes of patients returning for repeat tobacco dependence treatment publication-title: Int J Clin Pract doi: 10.1111/j.1742-1241.2006.01077.x contributor: fullname: Richardson – volume: 27 start-page: 105 year: 2002 end-page: 119 ident: CR8 article-title: Pharmacogenetics of tardive dyskinesia: combined analysis of 780 patients supports association with dopamine D3 receptor gene Ser9Gly polymorphism publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(02)00293-2 contributor: fullname: Cavallaro – volume: 160 start-page: 677 year: 2003 end-page: 679 ident: CR9 article-title: Polymorphism of the promoter region of the serotonin 5-HT(2C) receptor gene and clozapine-induced weight gain publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.160.4.677 contributor: fullname: Zhang – volume: 328 start-page: 1519 year: 2004 end-page: 1527 ident: CR55 article-title: Mortality in relation to smoking: 50 year's observations on male British doctors publication-title: BMJ doi: 10.1136/bmj.38142.554479.AE contributor: fullname: Sutherland – volume: 64 start-page: 218 year: 2007 end-page: 224 ident: CR5 article-title: Association of the adrenergic alpha2A receptor gene with methylphenidate improvement of inattentive symptoms in children and adolescents with attention-deficit/hyperactivity disorder publication-title: Arch Gen Psychiatry doi: 10.1001/archpsyc.64.2.218 contributor: fullname: Hutz – volume: 161 start-page: 2100 year: 2004 end-page: 2107 ident: CR44 article-title: Extended nortriptyline and psychological treatment for cigarette smoking publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.161.11.2100 contributor: fullname: Cullen – volume: 31 start-page: 144 year: 2005 end-page: 148 ident: CR10 article-title: Pharmacogenetics, ethical issues: review of the Nuffield Council on Bioethics Report publication-title: J Med Ethics doi: 10.1136/jme.2004.007229 contributor: fullname: Corrigan – volume: 6 start-page: 1 year: 2002 end-page: 245 ident: CR35 article-title: The clinical effectiveness and cost-effectiveness of bupropion and nicotine replacement therapy for smoking cessation: a systematic review and economic evaluation publication-title: Health Technol Assess doi: 10.3310/hta6160 contributor: fullname: Song – volume: 166 start-page: 1561 year: 2006 end-page: 1568 ident: CR19 article-title: Smoking cessation with varenicline, a selective alpha4beta2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up publication-title: Arch Intern Med doi: 10.1001/archinte.166.15.1561 contributor: fullname: Anziano – volume: 22 start-page: 481 year: 2004 end-page: 493 ident: CR28 article-title: The role of cost-effectiveness analysis in the era of pharmacogenomics publication-title: Pharmacoeconomics doi: 10.2165/00019053-200422080-00001 contributor: fullname: Veenstra – ident: CR60 – volume: 31 start-page: 231 year: 2006 end-page: 242 ident: CR7 article-title: Role of functional genetic variation in the dopamine D2 receptor (DRD2) in response to bupropion and nicotine replacement therapy for tobacco dependence: results of two randomized clinical trials publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300861 contributor: fullname: Patterson – volume: 59 start-page: 201 year: 2003 end-page: 206 ident: CR37 article-title: Cost-effectiveness analysis of the first-line therapies for nicotine dependence publication-title: Eur J Clin Pharmacol doi: 10.1007/s00228-003-0610-6 contributor: fullname: Paccaud – volume: 9 start-page: 442 year: 2004 end-page: 473 ident: CR2 article-title: Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001494 contributor: fullname: Roots – volume: 101 start-page: 1352 year: 2006 end-page: 1361 ident: CR40 article-title: The ATTEMPT cohort: a multi-national longitudinal study of predictors, patterns and consequences of smoking cessation; introduction and evaluation of internet recruitment and data collection methods [erratum appears in 2006 Oct;101:1528] publication-title: Addiction doi: 10.1111/j.1360-0443.2006.01534.x contributor: fullname: Nonnemaker – volume: 156 start-page: 994 year: 2002 end-page: 1001 ident: CR57 article-title: Smoking reduction, smoking cessation, and mortality: a 16-year follow-up of 19, 732 men and women from the Copenhagen centre for prospective population studies publication-title: Am J Epidemiol doi: 10.1093/aje/kwf150 contributor: fullname: Osler – volume: 26 start-page: 264 year: 1997 end-page: 270 ident: CR31 article-title: The cost-effectiveness of the nicotine transdermal patch for smoking cessation publication-title: Prev Med doi: 10.1006/pmed.1996.0127 contributor: fullname: Ahluwalia – volume: 145 start-page: 749 year: 2006 end-page: 757 ident: CR29 article-title: Pharmacogenomics: challenges and opportunities publication-title: Ann Intern Med doi: 10.7326/0003-4819-145-10-200611210-00007 contributor: fullname: Johnson – ident: CR14 – volume: 14 start-page: 335 year: 2004 end-page: 342 ident: CR27 article-title: Cost-effectiveness analysis of HLA B 5701 genotyping in preventing abacavir hypersensitivity publication-title: Pharmacogenetics doi: 10.1097/00008571-200406000-00002 contributor: fullname: Pirmohamed – volume: 74 start-page: 286 year: 2006 end-page: 294 ident: CR42 article-title: Extended treatment with bupropion SR for cigarette smoking cessation publication-title: J Consult Clin Psychol doi: 10.1037/0022-006X.74.2.286 contributor: fullname: Cromp – year: 2004 ident: CR15 publication-title: The Millennium Development Goals and Tobacco Control: An Opportunity for Global Partnership contributor: fullname: Leeder – volume: 9 start-page: 879 year: 2004 end-page: 889 ident: CR4 article-title: Investigation of serotonin-related genes in antidepressant response publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001502 contributor: fullname: Hamilton – volume: 6 start-page: S57 year: 1997 end-page: S62 ident: CR39 article-title: Predictors of smoking cessation in a cohort of adult smokers followed for five years publication-title: Tob Control doi: 10.1136/tc.6.suppl_2.S57 contributor: fullname: Hartwell – volume: 6 start-page: 229 year: 2004 end-page: 239 ident: CR47 article-title: The effects of the DRD2 polymorphism on smoking cessation and negative affect: evidence for a pharmacogenetic effect on mood publication-title: Nicotine Tob Res doi: 10.1080/14622200410001676396 contributor: fullname: Cinciripini – volume: 99 start-page: 29 year: 2004 end-page: 38 ident: CR53 article-title: Shape of the relapse curve and long-term abstinence among untreated smokers publication-title: Addiction doi: 10.1111/j.1360-0443.2004.00540.x contributor: fullname: Naud – volume: 296 start-page: 2480 year: 2006 end-page: 2482 ident: CR50 article-title: Potential for genetics to promote public health: genetics research on smoking suggests caution about expectations publication-title: JAMA doi: 10.1001/jama.296.20.2480 contributor: fullname: Burke – volume: 296 start-page: 47 year: 2006 end-page: 55 ident: CR20 article-title: Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial publication-title: JAMA doi: 10.1001/jama.296.1.47 contributor: fullname: Billing – volume: 55 start-page: 334 year: 2001 end-page: 335 ident: CR58 article-title: Smoking in adolescence and young adulthood and mortality in later life: prospective observational study publication-title: J Epidemiol Community Health doi: 10.1136/jech.55.5.334 contributor: fullname: McEwen – volume: 51 start-page: 642 year: 2002 end-page: 645 ident: CR38 article-title: Cigarette smoking among adults—United States 2000 publication-title: MMWR – volume: 354 start-page: 210 year: 1999 end-page: 215 ident: CR34 article-title: Prescription of transdermal nicotine patches for smoking cessation in general practice: evaluation of cost-effectiveness publication-title: Lancet doi: 10.1016/S0140-6736(99)90001-6 contributor: fullname: Russell – volume: 6 start-page: 211 year: 2005 end-page: 223 ident: CR1 article-title: Pharmacogenetics and nicotine addiction treatment publication-title: Pharmacogenomics doi: 10.1517/14622416.6.3.211 contributor: fullname: Lerman – volume: 15 start-page: 280 year: 2006 end-page: 285 ident: CR17 article-title: Nicotine replacement therapy for long-term smoking cessation: a meta-analysis publication-title: Tob Control doi: 10.1136/tc.2005.015487 contributor: fullname: Stapleton – volume: 79 start-page: 600 year: 2006 end-page: 608 ident: CR25 article-title: Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation publication-title: Clin Pharmacol Ther doi: 10.1016/j.clpt.2006.02.006 contributor: fullname: Pinto – volume: 140 start-page: 426 year: 2004 end-page: 433 ident: CR51 article-title: Individualizing nicotine replacement therapy for the treatment of tobacco dependence: a randomized trial publication-title: Ann Intern Med doi: 10.7326/0003-4819-140-6-200403160-00009 contributor: fullname: Audrain-McGovern – volume: 21 start-page: 1621 year: 2000 end-page: 1626 ident: CR59 article-title: Mortality from all causes and from coronary heart disease related to smoking and changes in smoking during a 35-year follow-up of middle-aged Finnish men publication-title: Eur Heart J doi: 10.1053/euhj.2000.2151 contributor: fullname: Tuomilehto – volume: 28 start-page: 1546 year: 2003 end-page: 1552 ident: CR6 article-title: A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300219 contributor: fullname: Volpicelli – volume: 275 start-page: 1247 year: 1996 end-page: 1251 ident: CR30 article-title: Cost-effectiveness of the transdermal nicotine patch as an adjunct to physicians’ smoking cessation counseling publication-title: JAMA doi: 10.1001/jama.1996.03530400035035 contributor: fullname: Franks – volume: 11 start-page: 429 year: 2006 end-page: 444 ident: CR21 article-title: Current and emerging pharmacotherapies for treating tobacco dependence publication-title: Expert Opin Emerg Drugs doi: 10.1517/14728214.11.3.429 contributor: fullname: Lerman – volume: 87 start-page: 706 year: 2001 end-page: 711 ident: CR56 article-title: A propensity analysis of cigarette smoking and mortality with consideration of the effects of alcohol publication-title: Am J Cardiol doi: 10.1016/S0002-9149(00)01487-9 contributor: fullname: Lauer – ident: CR13 – volume: 337 start-page: 1052 year: 1997 end-page: 1057 ident: CR49 article-title: The health care costs of smoking publication-title: N Engl J Med doi: 10.1056/NEJM199710093371506 contributor: fullname: van der Maas – volume: 22S5 start-page: S26 year: 2002 end-page: S37 ident: CR36 article-title: Cost-effectiveness of pharmacological interventions for smoking cessation: a literature review and a decision analytic analysis publication-title: Med Decis Making doi: 10.1177/027298902237708 contributor: fullname: Woolacott – volume: 53 start-page: 1 year: 2004 end-page: 38 ident: CR54 article-title: United States life tables, 2002 publication-title: Nat Vital Stat Rep contributor: fullname: Arias – volume: 339 start-page: 673 year: 1998 end-page: 679 ident: CR33 article-title: Use and cost effectiveness of smoking-cessation services under four insurance plans in a health maintenance organization publication-title: N Engl J Med doi: 10.1056/NEJM199809033391006 contributor: fullname: Pabiniak – volume: 4 start-page: 184 year: 2004 end-page: 192 ident: CR23 article-title: The functional mu opioid receptor (OPRM1) Asn40Asp variant predicts short-term response to nicotine replacement therapy in a clinical trial publication-title: Pharmacogenomics J doi: 10.1038/sj.tpj.6500238 contributor: fullname: Restine – volume: 1 start-page: CD000031 year: 2007 ident: CR16 article-title: Antidepressants for smoking cessation publication-title: Cochrane Database Syst Rev contributor: fullname: Lancaster – volume: 6 start-page: 300 year: 2006 ident: CR18 article-title: Effectiveness of smoking cessation therapies: a systematic review and meta-analysis publication-title: BMC Public Health doi: 10.1186/1471-2458-6-300 contributor: fullname: Mills – volume: 263 start-page: 2760 year: 1990 end-page: 2765 ident: CR52 article-title: Methods used to quit smoking in the United States. Do cessation programs help? publication-title: JAMA doi: 10.1001/jama.1990.03440200064024 contributor: fullname: Newcomb – volume: 156 start-page: 994 year: 2002 ident: BF6500492_CR57 publication-title: Am J Epidemiol doi: 10.1093/aje/kwf150 contributor: fullname: NS Gotfredsen – volume: 4 start-page: 184 year: 2004 ident: BF6500492_CR23 publication-title: Pharmacogenomics J doi: 10.1038/sj.tpj.6500238 contributor: fullname: C Lerman – volume: 11 start-page: 429 year: 2006 ident: BF6500492_CR21 publication-title: Expert Opin Emerg Drugs doi: 10.1517/14728214.11.3.429 contributor: fullname: RA Schnoll – ident: BF6500492_CR60 – volume-title: The Millennium Development Goals and Tobacco Control: An Opportunity for Global Partnership year: 2004 ident: BF6500492_CR15 contributor: fullname: KM Esson – volume: 9 start-page: 442 year: 2004 ident: BF6500492_CR2 publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001494 contributor: fullname: J Kirchheiner – volume: 328 start-page: 1519 year: 2004 ident: BF6500492_CR55 publication-title: BMJ doi: 10.1136/bmj.38142.554479.AE contributor: fullname: R Doll – volume: 64 start-page: 218 year: 2007 ident: BF6500492_CR5 publication-title: Arch Gen Psychiatry doi: 10.1001/archpsyc.64.2.218 contributor: fullname: G Polanczyk – ident: BF6500492_CR13 – volume: 53 start-page: 1 year: 2004 ident: BF6500492_CR54 publication-title: Nat Vital Stat Rep contributor: fullname: E Arias – volume: 6 start-page: 229 year: 2004 ident: BF6500492_CR47 publication-title: Nicotine Tob Res doi: 10.1080/14622200410001676396 contributor: fullname: P Cinciripini – volume: 51 start-page: 642 year: 2002 ident: BF6500492_CR38 publication-title: MMWR contributor: fullname: Centers for Disease Control and Prevention – volume: 62 start-page: 635 year: 2007 ident: BF6500492_CR24 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2006.10.005 contributor: fullname: AM Lee – volume: 8 start-page: E174 year: 2006 ident: BF6500492_CR22 publication-title: AAPS J doi: 10.1208/aapsj080121 contributor: fullname: JL Rutter – volume: 72 start-page: 917 year: 1997 ident: BF6500492_CR32 publication-title: Mayo Clin Proc doi: 10.1016/S0025-6196(11)63361-2 contributor: fullname: IT Croghan – volume: 59 start-page: 201 year: 2003 ident: BF6500492_CR37 publication-title: Eur J Clin Pharmacol doi: 10.1007/s00228-003-0610-6 contributor: fullname: J Cornuz – volume: 26 start-page: 264 year: 1997 ident: BF6500492_CR31 publication-title: Prev Med doi: 10.1006/pmed.1996.0127 contributor: fullname: MA Wasley – volume: 140 start-page: 426 year: 2004 ident: BF6500492_CR51 publication-title: Ann Intern Med doi: 10.7326/0003-4819-140-6-200403160-00009 contributor: fullname: C Lerman – volume: 101 start-page: 1352 year: 2006 ident: BF6500492_CR40 publication-title: Addiction doi: 10.1111/j.1360-0443.2006.01534.x contributor: fullname: R West – volume: 263 start-page: 2760 year: 1990 ident: BF6500492_CR52 publication-title: JAMA doi: 10.1001/jama.1990.03440200064024 contributor: fullname: MC Fiore – volume: 275 start-page: 1247 year: 1996 ident: BF6500492_CR30 publication-title: JAMA doi: 10.1001/jama.1996.03530400035035 contributor: fullname: K Fiscella – volume: 55 start-page: 334 year: 2001 ident: BF6500492_CR58 publication-title: J Epidemiol Community Health doi: 10.1136/jech.55.5.334 contributor: fullname: P McCarron – volume: 296 start-page: 47 year: 2006 ident: BF6500492_CR20 publication-title: JAMA doi: 10.1001/jama.296.1.47 contributor: fullname: D Gonzales – volume: 337 start-page: 1052 year: 1997 ident: BF6500492_CR49 publication-title: N Engl J Med doi: 10.1056/NEJM199710093371506 contributor: fullname: JJ Barendregt – volume: 6 start-page: S57 year: 1997 ident: BF6500492_CR39 publication-title: Tob Control doi: 10.1136/tc.6.suppl_2.S57 contributor: fullname: N Hymowitz – volume: 296 start-page: 2480 year: 2006 ident: BF6500492_CR50 publication-title: JAMA doi: 10.1001/jama.296.20.2480 contributor: fullname: C Carlsten – volume: 6S3 start-page: S363 year: 2004 ident: BF6500492_CR41 publication-title: Nicotine Tob Res doi: 10.1080/14622200412331320761 contributor: fullname: A Hyland – volume: 60 start-page: 1068 year: 2006 ident: BF6500492_CR45 publication-title: Int J Clin Pract doi: 10.1111/j.1742-1241.2006.01077.x contributor: fullname: ES Han – volume: 31 start-page: 293 year: 2006 ident: BF6500492_CR46 publication-title: Am J Prev Med doi: 10.1016/j.amepre.2006.06.021 contributor: fullname: MR Partin – volume: 161 start-page: 2100 year: 2004 ident: BF6500492_CR44 publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.161.11.2100 contributor: fullname: SM Hall – volume: 27 start-page: 105 year: 2002 ident: BF6500492_CR8 publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(02)00293-2 contributor: fullname: B Lerer – volume: 31 start-page: 144 year: 2005 ident: BF6500492_CR10 publication-title: J Med Ethics doi: 10.1136/jme.2004.007229 contributor: fullname: OP Corrigan – volume: 102 start-page: 11864 year: 2005 ident: BF6500492_CR48 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0500329102 contributor: fullname: QR Liu – volume: 31 start-page: 231 year: 2006 ident: BF6500492_CR7 publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300861 contributor: fullname: C Lerman – volume: 339 start-page: 673 year: 1998 ident: BF6500492_CR33 publication-title: N Engl J Med doi: 10.1056/NEJM199809033391006 contributor: fullname: SJ Curry – ident: BF6500492_CR14 – volume: 6 start-page: 1 year: 2002 ident: BF6500492_CR35 publication-title: Health Technol Assess doi: 10.3310/hta6160 contributor: fullname: NF Woolacott – volume: 74 start-page: 286 year: 2006 ident: BF6500492_CR42 publication-title: J Consult Clin Psychol doi: 10.1037/0022-006X.74.2.286 contributor: fullname: JD Killen – volume: 6 start-page: 211 year: 2005 ident: BF6500492_CR1 publication-title: Pharmacogenomics doi: 10.1517/14622416.6.3.211 contributor: fullname: MR Munafò – volume: 160 start-page: 677 year: 2003 ident: BF6500492_CR9 publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.160.4.677 contributor: fullname: GP Reynolds – volume: 11 start-page: 400 year: 2006 ident: BF6500492_CR26 publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001794 contributor: fullname: V Malaiyandi – volume: 23 start-page: 744 year: 2001 ident: BF6500492_CR43 publication-title: Clin Ther doi: 10.1016/S0149-2918(01)80023-0 contributor: fullname: BD Jamerson – volume: 79 start-page: 600 year: 2006 ident: BF6500492_CR25 publication-title: Clin Pharmacol Ther doi: 10.1016/j.clpt.2006.02.006 contributor: fullname: C Lerman – volume: 14 start-page: 335 year: 2004 ident: BF6500492_CR27 publication-title: Pharmacogenetics doi: 10.1097/00008571-200406000-00002 contributor: fullname: DA Hughes – volume: 354 start-page: 210 year: 1999 ident: BF6500492_CR34 publication-title: Lancet doi: 10.1016/S0140-6736(99)90001-6 contributor: fullname: JA Stapleton – volume: 145 start-page: 749 year: 2006 ident: BF6500492_CR29 publication-title: Ann Intern Med doi: 10.7326/0003-4819-145-10-200611210-00007 contributor: fullname: DM Roden – volume: 22S5 start-page: S26 year: 2002 ident: BF6500492_CR36 publication-title: Med Decis Making doi: 10.1177/027298902237708 contributor: fullname: F Song – volume: 6 start-page: 675 year: 2004 ident: BF6500492_CR11 publication-title: Nicotine Tob Res doi: 10.1080/14622200410001734058 contributor: fullname: A Shields – volume: 21 start-page: 1621 year: 2000 ident: BF6500492_CR59 publication-title: Eur Heart J doi: 10.1053/euhj.2000.2151 contributor: fullname: Q Qiao – volume: 28 start-page: 1546 year: 2003 ident: BF6500492_CR6 publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300219 contributor: fullname: DW Oslin – volume: 6 start-page: 300 year: 2006 ident: BF6500492_CR18 publication-title: BMC Public Health doi: 10.1186/1471-2458-6-300 contributor: fullname: P Wu – volume: 22 start-page: 481 year: 2004 ident: BF6500492_CR28 publication-title: Pharmacoeconomics doi: 10.2165/00019053-200422080-00001 contributor: fullname: CR Flowers – volume: 99 start-page: 29 year: 2004 ident: BF6500492_CR53 publication-title: Addiction doi: 10.1111/j.1360-0443.2004.00540.x contributor: fullname: JR Hughes – volume: 1 start-page: CD000031 year: 2007 ident: BF6500492_CR16 publication-title: Cochrane Database Syst Rev contributor: fullname: J Hughes – ident: BF6500492_CR12 – volume: 87 start-page: 706 year: 2001 ident: BF6500492_CR56 publication-title: Am J Cardiol doi: 10.1016/S0002-9149(00)01487-9 contributor: fullname: JM Foody – volume: 9 start-page: 879 year: 2004 ident: BF6500492_CR4 publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001502 contributor: fullname: EJ Peters – volume: 166 start-page: 1561 year: 2006 ident: BF6500492_CR19 publication-title: Arch Intern Med doi: 10.1001/archinte.166.15.1561 contributor: fullname: M Nides – volume: 158 start-page: 802 year: 2001 ident: BF6500492_CR3 publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.158.5.802 contributor: fullname: M Schafer – volume: 15 start-page: 280 year: 2006 ident: BF6500492_CR17 publication-title: Tob Control doi: 10.1136/tc.2005.015487 contributor: fullname: JF Etter – volume-title: Cost-Effectiveness in Health and Medicine year: 1996 ident: BF6500492_CR61 doi: 10.1093/oso/9780195108248.001.0001 contributor: fullname: MR Gold
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Snippet	We evaluated the cost-effectiveness of a range of smoking cessation drug treatments, including varenicline, transdermal nicotine (TN), bupropion and the use of...
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SubjectTerms	Benzazepines - administration & dosage Benzazepines - pharmacology Biomedical and Life Sciences Biomedicine Bupropion Bupropion - administration & dosage Bupropion - pharmacology Care and treatment Cigarette smoking Cost analysis Cost-Benefit Analysis Drug addiction Economic aspects Gene Expression Genetic aspects Genetic screening Genotype Human Genetics Humans Monte Carlo simulation Nicotine Oncology original-article Pharmacogenetics Pharmacotherapy Psychopharmacology Quinoxalines - administration & dosage Quinoxalines - pharmacology Receptors, Nicotinic - drug effects Sensitivity analysis Smokers Smoking Smoking Cessation - economics Smoking cessation products Varenicline
Title	Cost-effectiveness of pharmacogenetic testing to tailor smoking-cessation treatment
URI	http://dx.doi.org/10.1038/sj.tpj.6500492 https://link.springer.com/article/10.1038/sj.tpj.6500492 https://www.ncbi.nlm.nih.gov/pubmed/18347612 https://www.proquest.com/docview/227941664 https://www.proquest.com/docview/2641697927 https://search.proquest.com/docview/19573831 https://search.proquest.com/docview/69789009 https://pubmed.ncbi.nlm.nih.gov/PMC5618442
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