布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的疗效观察
目的：探讨布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的疗效。方法：选取鄂州市妇幼保健院2012年3月—2014年9月收治的140例支气管哮喘患儿,按随机数字表法分为2组各70例。观察组患儿给予布地奈德与特布他林联合雾化吸入,对照组患儿给予对症、常规支持治疗,治疗结束后,比较2组患儿的疗效及咳嗽、呼吸困难、肺部湿性啰音与喘憋消失时间,肺功能指标,不良反应发生情况。结果：观察组患儿总有效率为92.86%（65/70）,高于对照组的80.00%（56/70）,差异有统计学意义（P〈0.05）;观察组患儿咳嗽消失时间为（7.23±1.08）d,呼吸困难消失时间为（2.19±0.56）d,...
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| Published in | 中国医院用药评价与分析 Vol. 16; no. 4; pp. 451 - 453 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
鄂州市妇幼保健院儿科,湖北鄂州,436000
2016
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-2124 |
| DOI | 10.14009/j.issn.1672-2124.2016.04.008 |
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| Abstract | 目的：探讨布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的疗效。方法：选取鄂州市妇幼保健院2012年3月—2014年9月收治的140例支气管哮喘患儿,按随机数字表法分为2组各70例。观察组患儿给予布地奈德与特布他林联合雾化吸入,对照组患儿给予对症、常规支持治疗,治疗结束后,比较2组患儿的疗效及咳嗽、呼吸困难、肺部湿性啰音与喘憋消失时间,肺功能指标,不良反应发生情况。结果：观察组患儿总有效率为92.86%（65/70）,高于对照组的80.00%（56/70）,差异有统计学意义（P〈0.05）;观察组患儿咳嗽消失时间为（7.23±1.08）d,呼吸困难消失时间为（2.19±0.56）d,肺部湿性啰音消失时间为（2.23±1.49）d,喘憋消失时间为（2.12±1.20）d,均明显短于对照组的（8.34±2.47）、（3.46±1.02）、（3.89±2.68）、（3.57±2.39）d,差异有统计学意义（P〈0.05）。观察组患儿肺功能改善情况与对照组比较,差异有统计学意义（P〈0.05）;观察组患儿发生不良反应7例（10.00%）,对照组为14例（20.00%）,2组的差异有统计学意义（P〈0.05）。结论：布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的临床疗效显著,不良反应少,值得临床推广。 |
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| AbstractList | 目的：探讨布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的疗效。方法：选取鄂州市妇幼保健院2012年3月—2014年9月收治的140例支气管哮喘患儿,按随机数字表法分为2组各70例。观察组患儿给予布地奈德与特布他林联合雾化吸入,对照组患儿给予对症、常规支持治疗,治疗结束后,比较2组患儿的疗效及咳嗽、呼吸困难、肺部湿性啰音与喘憋消失时间,肺功能指标,不良反应发生情况。结果：观察组患儿总有效率为92.86%（65/70）,高于对照组的80.00%（56/70）,差异有统计学意义（P〈0.05）;观察组患儿咳嗽消失时间为（7.23±1.08）d,呼吸困难消失时间为（2.19±0.56）d,肺部湿性啰音消失时间为（2.23±1.49）d,喘憋消失时间为（2.12±1.20）d,均明显短于对照组的（8.34±2.47）、（3.46±1.02）、（3.89±2.68）、（3.57±2.39）d,差异有统计学意义（P〈0.05）。观察组患儿肺功能改善情况与对照组比较,差异有统计学意义（P〈0.05）;观察组患儿发生不良反应7例（10.00%）,对照组为14例（20.00%）,2组的差异有统计学意义（P〈0.05）。结论：布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的临床疗效显著,不良反应少,值得临床推广。 R974; 目的:探讨布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的疗效.方法:选取鄂州市妇幼保健院2012年3月—2014年9月收治的140例支气管哮喘患儿,按随机数字表法分为2组各70例.观察组患儿给予布地奈德与特布他林联合雾化吸入,对照组患儿给予对症、常规支持治疗,治疗结束后,比较2组患儿的疗效及咳嗽、呼吸困难、肺部湿性啰音与喘憋消失时间,肺功能指标,不良反应发生情况.结果:观察组患儿总有效率为92.86％(65/70),高于对照组的80.00％ (56/70),差异有统计学意义(P＜0.05);观察组患儿咳嗽消失时间为(7.23±1.08)d,呼吸困难消失时间为(2.19±0.56)d,肺部湿性啰音消失时间为(2.23±1.49)d,喘憋消失时间为(2.12±1.20)d,均明显短于对照组的(8.34±2.47)、(3.46±1.02)、(3.89±2.68)、(3.57±2.39)d,差异有统计学意义(P＜0.05).观察组患儿肺功能改善情况与对照组比较,差异有统计学意义(P＜0.05);观察组患儿发生不良反应7例(10.00％),对照组为14例(20.00％),2组的差异有统计学意义(P＜0.05).结论:布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的临床疗效显著,不良反应少,值得临床推广. |
| Author | 李红霞 |
| AuthorAffiliation | 鄂州市妇幼保健院儿科,湖北鄂州436000 |
| AuthorAffiliation_xml | – name: 鄂州市妇幼保健院儿科,湖北鄂州,436000 |
| Author_FL | LI Hongxia |
| Author_FL_xml | – sequence: 1 fullname: LI Hongxia |
| Author_xml | – sequence: 1 fullname: 李红霞 |
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| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
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| DocumentTitleAlternate | Observation on Clinical Efficacy of Budesonide Combined with Terbutaline Aerosol Inhalation in Treatment of Children with Acute Bronchial Asthma |
| DocumentTitle_FL | Observation on Clinical Efficacy of Budesonide Combined with Terbutaline Aerosol Inhalation in Treatment of Children with Acute Bronchial Asthma |
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| Keywords | Budesonide Clinical effect 布地奈德 Acute bronchial asthma Terbutaline aerosol inhalation 临床效果 特布他林雾化 支气管哮喘 |
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| Notes | LI Hongxia;Dept.of Pediatrics,Ezhou Maternal and Child Health Hospital; Hubei Ezhou 436000, China Budesonide; Terbutaline aerosol inhalation; Acute bronchial asthma; Clinical effect 11-4975/R OBJECTIVE：To probe into the clinical efficacy of budesonide combined with terbutaline aerosol inhalation in treatment of children with acute bronchial asthma.METHODS：140 cases of children with acute bronchial asthma admitted into Ezhou Maternal and Child Health Hospital from Mar.2012 to Sept.2014 were selected to be divided into two groups via the random number table,with 70 cases in each.The observation group were treated with budesonide and terbutaline aerosol inhalation,while the control group received symptomatic,conventional supportive treatment.After treatment,the efficacy and disappearance time of cough,dyspnea,lung moist rale and asthmatic suffocating,lung function indicators and incidence of adverse reactions were compared between two group of patients.RESULTS：The total effective rate of observation group was 92.86 |
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| Publisher | 鄂州市妇幼保健院儿科,湖北鄂州,436000 |
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| SubjectTerms | 临床效果 布地奈德 支气管哮喘 特布他林雾化 |
| Title | 布地奈德与特布他林联合雾化吸入治疗儿童支气管哮喘急性发作的疗效观察 |
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