Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder

• Published in: Biological psychiatry (1969) Vol. 89; no. 5; pp. 451 - 462
• Main Authors: Needham, Brittany D., Adame, Mark D., Serena, Gloria, Rose, Destanie R., Preston, Gregory M., Conrad, Mary C., Campbell, A. Stewart, Donabedian, David H., Fasano, Alessio, Ashwood, Paul, Mazmanian, Sarkis K.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2021
• Subjects: Animals; ASD; Autism Spectrum Disorder; Fecal metabolites; Feces; Gastrointestinal Microbiome; Metabolomics; Mice; Mitochondrial dysfunction; Phenolic metabolites; Pilot Projects; Plasma; Plasma metabolites; Psychiatric/Mental Health; Steroid hormones; Metabolomics; ASD; Mitochondrial dysfunction; Phenolic metabolites; Plasma metabolites; Autism spectrum disorder; Fecal metabolites; Steroid hormones

Autism spectrum disorder (ASD) is a neurodevelopmental condition with hallmark behavioral manifestations including impaired social communication and restricted repetitive behavior. In addition, many affected individuals display metabolic imbalances, immune dysregulation, gastrointestinal dysfunction...