Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma - Soroceanu, Liliana; Kharbanda, Samir; Chen, Ruihuan; Soriano, Robert H; Aldape, Ken; Misra, Anjan; Zha, Jiping; Forrest, William F; Nigro, Janice M; Modrusan, Zora; Feuerstein, Burt G; Phillips, Heidi S (Proceedings of the National Academy of Sciences - PNAS, 2007)
Keywords: Antibodies; Biological Sciences; Blotting, Western; Brain; carcinogenesis; Cell growth; Cell lines; Cell Proliferation; Comparative genomic hybridization; epidermal growth factor receptors; Gene Expression Profiling; gene overexpression; Genetic markers; Glioblastoma - metabolism; Glioblastoma - physiopathology; Glioma; Growth factors; Humans; Immunoprecipitation; In Situ Hybridization; Insulin; insulin-like growth factor I receptor; Insulin-Like Growth Factor II; Kinases; Messenger RNA; neoplasms; Neurons; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-Kinases - metabolism; Proteins - metabolism; Receptors; Receptors, Somatomedin - metabolism; Signal amplification; Signal Transduction - physiology; stem cells; Tumors