阿法骨化醇联合鲑鱼降钙素治疗重度骨质疏松症腰背部疼痛的疗效观察

目的：探讨阿法骨化醇联合鲑鱼降钙素治疗重度骨质疏松症伴腰背部疼痛的临床疗效。方法：选取2013年3月—2016年3月湖北省谷城县人民医院收治的骨质疏松症伴腰背部疼痛患者160例作为研究对象。根据随机双色球分组法将患者分为观察组和对照组,每组各80例。对照组患者给予鲑鱼降钙素,观察组患者在对照组的基础上加用阿法骨化醇。观察2组患者的临床疗效。结果：观察组患者的总有效率为95.0%（76/80）,明显高于对照组的77.5%（62/80）,差异有统计学意义（P〈0.05）。治疗后,观察组患者的骨钙素水平、尿羟脯氨酸水平均显著低于对照组,差异均有统计学意义（P〈0.05）。结论：采用阿法骨化醇与鲑鱼降...

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Bibliographic Details
Published in中国医院用药评价与分析 Vol. 17; no. 1; pp. 50 - 51
Main Author 邹涛 张自红 周凯
Format Journal Article
LanguageChinese
Published 湖北省谷城县人民医院康复科,湖北谷城,441700 2017
Subjects
腰背部疼痛
阿法骨化醇
骨质疏松症
鲑鱼降钙素
Osteoporosis
Salmon calcitonin
腰背部疼痛
阿法骨化醇
Low back pain
骨质疏松症
Alfacalcidol
鲑鱼降钙素
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ISSN1672-2124
DOI10.14009/j.issn.1672-2124.2017.01.017

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Summary:目的：探讨阿法骨化醇联合鲑鱼降钙素治疗重度骨质疏松症伴腰背部疼痛的临床疗效。方法：选取2013年3月—2016年3月湖北省谷城县人民医院收治的骨质疏松症伴腰背部疼痛患者160例作为研究对象。根据随机双色球分组法将患者分为观察组和对照组,每组各80例。对照组患者给予鲑鱼降钙素,观察组患者在对照组的基础上加用阿法骨化醇。观察2组患者的临床疗效。结果：观察组患者的总有效率为95.0%（76/80）,明显高于对照组的77.5%（62/80）,差异有统计学意义（P〈0.05）。治疗后,观察组患者的骨钙素水平、尿羟脯氨酸水平均显著低于对照组,差异均有统计学意义（P〈0.05）。结论：采用阿法骨化醇与鲑鱼降钙素联合治疗重度骨质疏松症伴腰背部疼痛的疗效显著,可有效减轻患者疼痛。
Bibliography:Osteoporosis; Low back pain; Salmon calcitonin; Alfacalcidol
ZOU Tao, ZHANG Zihong, ZHOU Kai （Dept. of Rehabilitation, Hubei Gucheng County People＇s Hospital, Hubei Gucheng 441700, China）
11-4975/R
OBJECTIVE： To probe into the clinical efficacy of alfacalcidol combined with salmon calcitonin in treatment of severe osteoporosis complicated with low back pain. METHODS： 160 patients with severe osteoporosis complicated with low back pain admitted into Hubei Gucheng County People＇s Hospital from Apr. 2013 to Apr. 2016 were selected to be divided into observation group and control group via the random double chromosphere group method,with 80 cases in each. The control group were given salmon calcitonin,while the observation group additionally received alfacalcidol based on the conbtrol group. The clinical efficacy of two groups were observed. RESULTS： The total effective rate of observation group was 95. 0%（ 76 /80）,significantly higher than that of control group [77. 5%（ 62 /80） ],with statistically significant diff
ISSN:1672-2124
DOI:10.14009/j.issn.1672-2124.2017.01.017