Progression of Abdominal Aortic Aneurysm Towards Rupture: Refining Clinical Risk Assessment Using a Fully Coupled Fluid–Structure Interaction Method

• Published in: Annals of biomedical engineering Vol. 43; no. 1; pp. 139 - 153
• Main Authors: Xenos, Michalis, Labropoulos, Nicos, Rambhia, Suraj, Alemu, Yared, Einav, Shmuel, Tassiopoulos, Apostolos, Sakalihasan, Natzi, Bluestein, Danny
• Format: Journal Article Web Resource
• Language: English
• Published: Boston Springer US 01.01.2015; Springer Nature B.V; Kluwer Academic Publishers
• Subjects: Aorta - physiology; Aortic Aneurysm, Abdominal - diagnostic imaging; Aortic Aneurysm, Abdominal - physiopathology; Aortic Rupture - diagnostic imaging; Aortic Rupture - physiopathology; Aortography; Biochemistry; Biological and Medical Physics; Biomechanical Phenomena; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Biophysics; Blood vessels; Chirurgie; Classical Mechanics; Computed tomography; Computer simulation; Disease Progression; Female; Human health sciences; Humans; Male; Mathematical models; Models, Cardiovascular; Progressions; Regional Blood Flow; Risk; Risk assessment; Rupture; Sciences de la santé humaine; Statistical models; Strength; Stresses; Surgery; Tomography, X-Ray Computed; Trends; Reconstruction of patient-based geometry; Rupture of abdominal aortic aneurysm; Rupture potential index; Fluid-structure interaction

Rupture of abdominal aortic aneurysm (AAA) is associated with high mortality rates. Risk of rupture is multi-factorial involving AAA geometric configuration, vessel tortuosity, and the presence of intraluminal pathology. Fluid structure interaction (FSI) simulations were conducted in patient based c...