Clinical Manifestations and Amplitude-integrated Encephalogram in Neonates with Early-onset Epileptic Encephalopathy

• Published in: Chinese medical journal Vol. 130; no. 23; pp. 2808 - 2815
• Main Authors: Liu, Li-Li, Hou, Xin-Lin, Zhang, Dan-Dan, Sun, Guo-Yu, Zhou, Cong-Le, Jiang, Yi, Tang, Ze-Zhong, Zhang, Rui, Cui, Yun
• Format: Journal Article
• Language: English
• Published: China Medknow Publications and Media Pvt. Ltd 05.12.2017; Lippincott Williams & Wilkins Ovid Technologies; Department of Pediatrics, Peking University First Hospital, Beijing 100034, China%Shenzhen Key Laboratory of Affective and Social Cognitive Science, College of Psychology and Sociology, Shenzhen University, Shenzhen, Guangdong 518060, China; Medknow Publications & Media Pvt Ltd; Wolters Kluwer
• Subjects: Amplitude-integrated Electroencepholography; Early-onset Epileptic Encephalopathy; Neonatal-onset; Newborn; Anticonvulsants - therapeutic use; Diagnosis; Early Diagnosis; Electroencephalography; Electroencephalography - methods; Encephalopathy; Epilepsy; Female; Health aspects; Humans; Infant; Infant, Newborn; Male; Medical prognosis; Mutation; Newborn babies; Newborn infants; Original; Patients; Pediatrics; Risk Factors; Seizures - diagnosis; Seizures - drug therapy; Sleep; Studies; Neonatal-onset; Newborn; Amplitude-integrated Electroencepholography; Early-onset Epileptic Encephalopathy

Background： The patients with early-onset epileptic encephalopathy （EOEE） suffer from neurodevelopmental delay. The aim of this study was to analyze the clinical manifestations and amplitude-integrated encephalogram （aEEG） characteristics of infants with EOEE with onset within the neonatal period, t...