Hypometabolism and Altered Cerebrospinal Fluid Markers in Normal Apolipoprotein E E4 Carriers with Subjective Memory Complaints - Mosconi, Lisa; De Santi, Susan; Brys, Miroslaw; Tsui, Wai H.; Pirraglia, Elizabeth; Glodzik-Sobanska, Lidia; Rich, Kenneth E.; Switalski, Remigius; Mehta, Pankaj D.; Pratico, Domenico; Zinkowski, Ray; Blennow, Kay; et al. (Biological psychiatry (1969), 2008)
Keywords: Adult and adolescent clinical studies; Aged; Alzheimer Disease - cerebrospinal fluid; Alzheimer Disease - genetics; Alzheimer’s disease; amyloid beta; Amyloid beta-Peptides - cerebrospinal fluid; ApoE; Apolipoprotein E4 - genetics; Biological and medical sciences; Biomarkers - cerebrospinal fluid; Blood Glucose - metabolism; Brain - diagnostic imaging; Brain - metabolism; CSF; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Energy Metabolism - genetics; FDG-PET; Female; Fluorodeoxyglucose F18; Genetic Carrier Screening; Humans; isoprostane; Male; Medical sciences; Memory Disorders - cerebrospinal fluid; Memory Disorders - genetics; Middle Aged; Neurology; Neurosciences; Neurovetenskaper; normal aging; Organic mental disorders. Neuropsychology; Peptide Fragments - cerebrospinal fluid; Positron-Emission Tomography; Psychiatric/Mental Health; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Reference Values; subjective memory complaints; tau; tau Proteins - cerebrospinal fluid; FDG-PET; subjective memory complaints; Alzheimer’s disease; CSF; normal aging; tau; ApoE; isoprostane; amyloid beta; Radionuclide study; Memory disorder; Senescence; Cognitive disorder; Self evaluation; Alzheimer disease; Cerebrospinal fluid; Apolipoprotein E; Degenerative disease; Memory complaint; Alzheimer's disease; Nervous system diseases; Cerebral disorder; Tau protein; β Amyloid protein; Central nervous system disease; Positron emission tomography; Emission tomography