Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome - Lee, Yong-Seok; Ehninger, Dan; Zhou, Miou; Oh, Jun-Young; Kang, Minkyung; Kwak, Chuljung; Ryu, Hyun-Hee; Butz, Delana; Araki, Toshiyuki; Cai, Ying; Balaji, J; Sano, Yoshitake; et al. (Nature neuroscience, 2014)
Keywords: 631/378/1689/2608; 64/110; 64/60; 82/51; 9/30; 9/74; Animal Genetics and Genomics; Animals; Behavioral Sciences; Biological Techniques; Biomedicine; Brain research; Care and treatment; Disease Models, Animal; Female; Genetic disorders; Genotype & phenotype; Humans; Kinases; Learning - drug effects; Learning - physiology; Learning disabilities; Long-Term Potentiation - drug effects; Long-Term Potentiation - physiology; Lovastatin - pharmacology; Lovastatin - therapeutic use; Male; Maze Learning - drug effects; Maze Learning - physiology; Memory; Memory Disorders - drug therapy; Memory Disorders - physiopathology; Memory, Disorders of; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mutation; Neurobiology; Neurosciences; Noonan syndrome; Noonan Syndrome - drug therapy; Noonan Syndrome - physiopathology; Physiological aspects; Random Allocation; Rats; Treatment Outcome; Los Angeles California; United States--US; California