Simultaneous pure T2 and varying T2′-weighted BOLD fMRI using Echo Planar Time-resolved Imaging for mapping cortical-depth dependent responses

• Published in: NeuroImage (Orlando, Fla.) Vol. 245; p. 118641
• Main Authors: Wang, Fuyixue, Dong, Zijing, Wald, Lawrence L., Polimeni, Jonathan R., Setsompop, Kawin
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 15.12.2021; Elsevier
• Subjects: Laminar fMRI; Microvascular specificity; Multi-echo; Spin-echo; T2 BOLD; Ultra-high field; Ultra-high field; Spin-echo; T2 BOLD; Microvascular specificity; Laminar fMRI; Multi-echo

Spin-echo (SE) BOLD fMRI has high microvascular specificity, and thus provides a more reliable means to localize neural activity compared to conventional gradient-echo BOLD fMRI. However, the most common SE BOLD acquisition method, SE-EPI, is known to suffer from T2′ contrast contamination with unde...