Hepatic stellate cell is activated by microRNA-181b via PTEN/Akt pathway - Zheng, Jianjian; Wu, Cunzao; Xu, Ziqiang; Xia, Peng; Dong, Peihong; Chen, Bicheng; Yu, Fujun (Molecular and cellular biochemistry, 2015)
Keywords: 3' Untranslated Regions - genetics; Actins - genetics; Actins - metabolism; Animals; Biochemistry; Biomedical and Life Sciences; Blotting, Western; Bone morphogenetic proteins; Carbon Tetrachloride; Cardiology; Cell Line; Cells; Chromones - pharmacology; Collagen; Collagen Type I - genetics; Collagen Type I - metabolism; Gene Expression - drug effects; Hepatic Stellate Cells - drug effects; Hepatic Stellate Cells - metabolism; Hepatology; Humans; Life Sciences; Liver Cirrhosis - chemically induced; Liver Cirrhosis - genetics; Liver Cirrhosis - metabolism; Liver diseases; Male; Medical Biochemistry; MicroRNA; MicroRNAs - genetics; Morpholines - pharmacology; Muscle proteins; Muscle, Smooth - metabolism; Oncology; Phosphatidylinositol 3-Kinases - antagonists & inhibitors; Phosphatidylinositol 3-Kinases - metabolism; Phosphorylation - drug effects; Proto-Oncogene Proteins c-akt - metabolism; PTEN Phosphohydrolase - genetics; PTEN Phosphohydrolase - metabolism; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleic acid; RNA; Signal Transduction - drug effects; Transforming Growth Factor beta1 - pharmacology; Transforming growth factors; PTEN; Hepatic stellate cells; TGF-β1; microRNA-181b