Dietary modulation of the gut microbiota – a randomised controlled trial in obese postmenopausal women

• Published in: British journal of nutrition Vol. 114; no. 3; pp. 406 - 417
• Main Authors: Brahe, Lena K., Le Chatelier, Emmanuelle, Prifti, Edi, Pons, Nicolas, Kennedy, Sean, Blædel, Trine, Håkansson, Janet, Dalsgaard, Trine Kastrup, Hansen, Torben, Pedersen, Oluf, Astrup, Arne, Ehrlich, S. Dusko, Larsen, Lesli H.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 14.08.2015; Cambridge University Press (CUP)
• Subjects: Aged; blood serum; c-peptide; C-Peptide - blood; Diabetes; Diet; DNA; Feces - microbiology; Female; Flax; Genes; Glucose; Glucose Tolerance Test; glucose tolerance tests; Homeostasis; Human and Clinical Nutrition; Human health and pathology; Human subjects; Humans; Insulin; Insulin - metabolism; Insulin Resistance; Insulin Secretion; Intervention; intestinal microorganisms; Intestines - microbiology; Lactobacillus; Lactobacillus paracasei; Life Sciences; linear models; linseed; metabolic diseases; Metabolic disorders; metagenomics; Microbiology and Parasitology; Microbiota; Middle Aged; Nutrition research; nutritional intervention; Obesity; Obesity - complications; Obesity - diet therapy; Obesity - microbiology; placebos; Plant Mucilage - administration & dosage; Postmenopause; Prebiotics; Probiotics; Probiotics - therapeutic use; Proteins; randomized clinical trials; regression analysis; Relative abundance; risk factors; Single-Blind Method; women; Womens health; Denmark; Gut microbiota; Flaxseed mucilage; Probiotics; Metagenomics; Obesity-related disease

The gut microbiota has been implicated in obesity and its progression towards metabolic disease. Dietary interventions that target the gut microbiota have been suggested to improve metabolic health. The aim of the present study was to investigate the effect of interventions with Lactobacillus paraca...