Rapid brain MRI acquisition techniques at ultra-high fields

Ultra‐high‐field MRI provides large increases in signal‐to‐noise ratio (SNR) as well as enhancement of several contrast mechanisms in both structural and functional imaging. Combined, these gains result in a substantial boost in contrast‐to‐noise ratio that can be exploited for higher‐spatial‐resolu...

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Published inNMR in biomedicine Vol. 29; no. 9; pp. 1198 - 1221
Main Authors Setsompop, Kawin, Feinberg, David A., Polimeni, Jonathan R.
Format Journal Article
LanguageEnglish
Published England Blackwell Publishing Ltd 01.09.2016
Wiley Subscription Services, Inc
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Abstract Ultra‐high‐field MRI provides large increases in signal‐to‐noise ratio (SNR) as well as enhancement of several contrast mechanisms in both structural and functional imaging. Combined, these gains result in a substantial boost in contrast‐to‐noise ratio that can be exploited for higher‐spatial‐resolution imaging to extract finer‐scale information about the brain. With increased spatial resolution, however, there is a concurrent increased image‐encoding burden that can cause unacceptably long scan times for structural imaging and slow temporal sampling of the hemodynamic response in functional MRI – particularly when whole‐brain imaging is desired. To address this issue, new directions of imaging technology development – such as the move from conventional 2D slice‐by‐slice imaging to more efficient simultaneous multislice (SMS) or multiband imaging (which can be viewed as “pseudo‐3D” encoding) as well as full 3D imaging – have provided dramatic improvements in acquisition speed. Such imaging paradigms provide higher SNR efficiency as well as improved encoding efficiency. Moreover, SMS and 3D imaging can make better use of coil sensitivity information in multichannel receiver arrays used for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher in these imaging acquisition schemes, with low image artifact levels and high SNR. Here we review the latest developments of SMS and 3D imaging methods and related technologies at ultra‐high field for rapid high‐resolution functional and structural imaging of the brain. Copyright © 2016 John Wiley & Sons, Ltd. Recent development trends in moving away from 2D imaging to simultaneous multislice (SMS) and 3D imaging have provided dramatic improvements in acquisition speed and SNR efficiency for high‐resolution imaging at ultra‐high field. SMS and 3D imaging can make better use of coil sensitivity information for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher, with low artifact levels and high SNR.
AbstractList Ultra‐high‐field MRI provides large increases in signal‐to‐noise ratio (SNR) as well as enhancement of several contrast mechanisms in both structural and functional imaging. Combined, these gains result in a substantial boost in contrast‐to‐noise ratio that can be exploited for higher‐spatial‐resolution imaging to extract finer‐scale information about the brain. With increased spatial resolution, however, there is a concurrent increased image‐encoding burden that can cause unacceptably long scan times for structural imaging and slow temporal sampling of the hemodynamic response in functional MRI – particularly when whole‐brain imaging is desired. To address this issue, new directions of imaging technology development – such as the move from conventional 2D slice‐by‐slice imaging to more efficient simultaneous multislice (SMS) or multiband imaging (which can be viewed as “pseudo‐3D” encoding) as well as full 3D imaging – have provided dramatic improvements in acquisition speed. Such imaging paradigms provide higher SNR efficiency as well as improved encoding efficiency. Moreover, SMS and 3D imaging can make better use of coil sensitivity information in multichannel receiver arrays used for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher in these imaging acquisition schemes, with low image artifact levels and high SNR. Here we review the latest developments of SMS and 3D imaging methods and related technologies at ultra‐high field for rapid high‐resolution functional and structural imaging of the brain. Copyright © 2016 John Wiley & Sons, Ltd. Recent development trends in moving away from 2D imaging to simultaneous multislice (SMS) and 3D imaging have provided dramatic improvements in acquisition speed and SNR efficiency for high‐resolution imaging at ultra‐high field. SMS and 3D imaging can make better use of coil sensitivity information for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher, with low artifact levels and high SNR.
Ultra-high-field MRI provides large increases in signal-to-noise ratio as well as enhancement of several contrast mechanisms in both structural and functional imaging. Combined, these gains result in a substantial boost in contrast-to-noise ratio that can be exploited for higher spatial resolution imaging to extract finer-scale information about the brain. With increased spatial resolution, however, is a concurrent increased image encoding burden that can cause unacceptably long scan times for structural imaging and slow temporal sampling of the hemodynamic response in functional MRI—particularly when whole-brain imaging is desired. To address this issue, new directions of imaging technology development—such as the move from conventional 2D slice-by-slice imaging to more efficient Simultaneous MultiSlice (SMS) or MultiBand imaging (which can be viewed as “pseudo-3D” encoding) as well as full 3D imaging—have provided dramatic improvements in acquisition speed. Such imaging paradigms provide higher SNR efficiency as well as improved encoding efficiency. Moreover, SMS and 3D imaging can make better use of coil sensitivity information in multi-channel receiver arrays used for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher in these imaging acquisition schemes, with low image artifact levels and high SNR. Here we review the latest developments of SMS and 3D imaging methods and related technologies at ultra-high field for rapid high-resolution functional and structural imaging of the brain.
Ultra‐high‐field MRI provides large increases in signal‐to‐noise ratio (SNR) as well as enhancement of several contrast mechanisms in both structural and functional imaging. Combined, these gains result in a substantial boost in contrast‐to‐noise ratio that can be exploited for higher‐spatial‐resolution imaging to extract finer‐scale information about the brain. With increased spatial resolution, however, there is a concurrent increased image‐encoding burden that can cause unacceptably long scan times for structural imaging and slow temporal sampling of the hemodynamic response in functional MRI – particularly when whole‐brain imaging is desired. To address this issue, new directions of imaging technology development – such as the move from conventional 2D slice‐by‐slice imaging to more efficient simultaneous multislice (SMS) or multiband imaging (which can be viewed as “pseudo‐3D” encoding) as well as full 3D imaging – have provided dramatic improvements in acquisition speed. Such imaging paradigms provide higher SNR efficiency as well as improved encoding efficiency. Moreover, SMS and 3D imaging can make better use of coil sensitivity information in multichannel receiver arrays used for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher in these imaging acquisition schemes, with low image artifact levels and high SNR. Here we review the latest developments of SMS and 3D imaging methods and related technologies at ultra‐high field for rapid high‐resolution functional and structural imaging of the brain. Copyright © 2016 John Wiley & Sons, Ltd.
Ultra-high-field MRI provides large increases in signal-to-noise ratio (SNR) as well as enhancement of several contrast mechanisms in both structural and functional imaging. Combined, these gains result in a substantial boost in contrast-to-noise ratio that can be exploited for higher-spatial-resolution imaging to extract finer-scale information about the brain. With increased spatial resolution, however, there is a concurrent increased image-encoding burden that can cause unacceptably long scan times for structural imaging and slow temporal sampling of the hemodynamic response in functional MRI - particularly when whole-brain imaging is desired. To address this issue, new directions of imaging technology development - such as the move from conventional 2D slice-by-slice imaging to more efficient simultaneous multislice (SMS) or multiband imaging (which can be viewed as "pseudo-3D" encoding) as well as full 3D imaging - have provided dramatic improvements in acquisition speed. Such imaging paradigms provide higher SNR efficiency as well as improved encoding efficiency. Moreover, SMS and 3D imaging can make better use of coil sensitivity information in multichannel receiver arrays used for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher in these imaging acquisition schemes, with low image artifact levels and high SNR. Here we review the latest developments of SMS and 3D imaging methods and related technologies at ultra-high field for rapid high-resolution functional and structural imaging of the brain. Recent development trends in moving away from 2D imaging to simultaneous multislice (SMS) and 3D imaging have provided dramatic improvements in acquisition speed and SNR efficiency for high-resolution imaging at ultra-high field. SMS and 3D imaging can make better use of coil sensitivity information for parallel imaging acquisitions through controlled aliasing in multiple spatial directions. This has enabled unprecedented acceleration factors of an order of magnitude or higher, with low artifact levels and high SNR.
Author Polimeni, Jonathan R.
Feinberg, David A.
Setsompop, Kawin
AuthorAffiliation 4 Advanced MRI Technologies, Sebastopol, CA, USA
2 Department of Radiology, Harvard Medical School, Boston, MA, USA
1 Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
3 Helen Wills Institute for Neuroscience, University of California, Berkeley, CA, USA
AuthorAffiliation_xml – name: 4 Advanced MRI Technologies, Sebastopol, CA, USA
– name: 2 Department of Radiology, Harvard Medical School, Boston, MA, USA
– name: 3 Helen Wills Institute for Neuroscience, University of California, Berkeley, CA, USA
– name: 1 Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
Author_xml – sequence: 1
  givenname: Kawin
  surname: Setsompop
  fullname: Setsompop, Kawin
  email: kawin@nmr.mgh.harvard.edu
  organization: Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
– sequence: 2
  givenname: David A.
  surname: Feinberg
  fullname: Feinberg, David A.
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– sequence: 3
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  surname: Polimeni
  fullname: Polimeni, Jonathan R.
  organization: Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
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Issue 9
Keywords 3D-EPI
wave-CAIPI
3D imaging
CAIPIRINHA
simultaneous multislice, multiband, blipped-CAIPI
simultaneous multislice RF pulse design
Language English
License http://onlinelibrary.wiley.com/termsAndConditions#vor
Copyright © 2016 John Wiley & Sons, Ltd.
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PMID 26835884
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PublicationTitle NMR in biomedicine
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Snippet Ultra‐high‐field MRI provides large increases in signal‐to‐noise ratio (SNR) as well as enhancement of several contrast mechanisms in both structural and...
Ultra-high-field MRI provides large increases in signal-to-noise ratio (SNR) as well as enhancement of several contrast mechanisms in both structural and...
Ultra-high-field MRI provides large increases in signal-to-noise ratio as well as enhancement of several contrast mechanisms in both structural and functional...
SourceID pubmedcentral
proquest
pubmed
crossref
wiley
istex
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 1198
SubjectTerms 3D imaging
3D-EPI
Algorithms
blipped-CAIPI
Brain - anatomy & histology
CAIPIRINHA
Humans
Image Enhancement - methods
Image Interpretation, Computer-Assisted - methods
Imaging, Three-Dimensional - methods
Magnetic Fields
Magnetic Resonance Imaging - methods
multiband
Radiation Dosage
Reproducibility of Results
Sensitivity and Specificity
Signal Processing, Computer-Assisted
simultaneous multislice
simultaneous multislice RF pulse design
simultaneous multislice, multiband, blipped‐CAIPI
wave-CAIPI
Title Rapid brain MRI acquisition techniques at ultra-high fields
URI https://api.istex.fr/ark:/67375/WNG-HTK02QC0-7/fulltext.pdf
https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fnbm.3478
https://www.ncbi.nlm.nih.gov/pubmed/26835884
https://www.proquest.com/docview/1812451164
https://www.proquest.com/docview/1812885921
https://www.proquest.com/docview/1815692275
https://pubmed.ncbi.nlm.nih.gov/PMC5245168
Volume 29
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