Serum IL-6 and PTX3 predict severe outcome from COVID-19 in ambulatory subjects: Impact for future therapeutic decisions - Poorbaugh, Josh; Sims, Jonathan T.; Zhang, Lin; Chang, Ching-Yun; Higgs, Richard E.; Nirula, Ajay; Benschop, Robert J. (PloS one, 2025)
Keywords: Adult; Aged; Biological markers; Biology and life sciences; Biomarkers; Biomarkers - blood; C-Reactive Protein - analysis; C-Reactive Protein - metabolism; Chemokines; Clinical trials; COVID-19; COVID-19 - blood; COVID-19 - mortality; COVID-19 - therapy; CXCL10 protein; Cytokines; Death; Decisions; Demographics; Demography; Disease transmission; Female; Health aspects; Health care; Hospital systems; Hospitalization; Hospitals; Humans; Identification and classification; Immune response; Infections; Interleukin 1 receptor antagonist; Interleukin 1 receptors; Interleukin 6; Interleukin-6 - blood; Male; Measurement; Medicine and health sciences; Membrane proteins; Middle Aged; Monoclonal antibodies; Mortality; Neutrophils; Patients; Physical Sciences; Prognosis; Proteins; Research and Analysis Methods; Risk groups; SARS-CoV-2; Serum Amyloid P-Component - analysis; Serum Amyloid P-Component - metabolism; Serum proteins; Severe acute respiratory syndrome coronavirus 2; Viral diseases; United States