Relationship of urinary bisphenol A in childhood on thyroid hormone function in adolescents: a cohort study

Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to...

Full description

Saved in:
Bibliographic Details
Published inPloS one Vol. 20; no. 5; p. e0322658
Main Authors Choi, Jung Eun, Choi, Eun Jeong, Lee, Seonhwa, Park, Bohyun, Lee, Hye Ah, Hong, Young Sun, Ha, Eunhee, Kim, Hae Soon, Park, Hyesook
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 22.05.2025
Public Library of Science (PLoS)
Subjects
Adolescent
Adolescents
Age
Benzhydryl Compounds - urine
Biology and Life Sciences
Bisphenol A
Bisphenol A Compounds
Body mass index
Child
Child, Preschool
Childhood
Children
Children & youth
Cohort analysis
Cohort Studies
Creatinine
Demographic aspects
Ecology and Environmental Sciences
Education
Endocrine disruptors
Endocrine Disruptors - urine
Environmental Exposure
Epoxy resins
Exposure
Female
Food
Generalized linear models
Girls
Health aspects
Hormones
Humans
Immunoassay
Male
Mass spectrometry
Measurement
Medical examination
Medicine and Health Sciences
Normal distribution
People and Places
Phenols - urine
Physical Sciences
Polycarbonate
Polymers
Regression analysis
Research and Analysis Methods
Scientific imaging
Serum levels
Social Sciences
Statistical analysis
Subgroups
Teenage girls
Thyroid
Thyroid diseases
Thyroid gland
Thyroid gland function tests
Thyroid hormones
Thyroid Hormones - blood
Thyroid-stimulating hormone
Thyrotropin - blood
Thyroxine
Thyroxine - blood
Tobacco smoke
Trends
Triiodothyronine
Triiodothyronine - blood
Xenoestrogens
South Korea
United States > US
Online AccessGet full text

Cover

Abstract Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea. Participants were drawn from the Ewha Birth and Growth Cohort Study, encompassing individuals who visited Ewha Women's Mokdong Hospital between 2001 and 2005. The concentration of urinary BPA was repeatedly measured for each subject at ages 3-5 years and 7-9 years. Serum levels of free triiothyronine (T3), free thyroxine (T4), and thyroid-stimulating hormone (TSH) were measured at ages 10-12 years in a subgroup of 128 out of 164 subjects who had undergone repeated BPA concentration measurements. We utilized the SAS program to analyze possible links between childhood exposure to BPA and thyroid hormone function in adolescence. Additionally, we explored how exposure to BPA during two specific periods influenced changes in thyroid hormone levels. The study observed that urinary BPA levels at ages 3-5 years were not notably linked to thyroid hormone levels in adolescents aged 10-12 years. However, BPA levels at ages 7-9 years were significantly associated with free T3 levels in girls aged 10-12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations. BPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.
AbstractList Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea.BACKGROUNDBisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea.Participants were drawn from the Ewha Birth and Growth Cohort Study, encompassing individuals who visited Ewha Women's Mokdong Hospital between 2001 and 2005. The concentration of urinary BPA was repeatedly measured for each subject at ages 3-5 years and 7-9 years. Serum levels of free triiothyronine (T3), free thyroxine (T4), and thyroid-stimulating hormone (TSH) were measured at ages 10-12 years in a subgroup of 128 out of 164 subjects who had undergone repeated BPA concentration measurements. We utilized the SAS program to analyze possible links between childhood exposure to BPA and thyroid hormone function in adolescence. Additionally, we explored how exposure to BPA during two specific periods influenced changes in thyroid hormone levels.METHODSParticipants were drawn from the Ewha Birth and Growth Cohort Study, encompassing individuals who visited Ewha Women's Mokdong Hospital between 2001 and 2005. The concentration of urinary BPA was repeatedly measured for each subject at ages 3-5 years and 7-9 years. Serum levels of free triiothyronine (T3), free thyroxine (T4), and thyroid-stimulating hormone (TSH) were measured at ages 10-12 years in a subgroup of 128 out of 164 subjects who had undergone repeated BPA concentration measurements. We utilized the SAS program to analyze possible links between childhood exposure to BPA and thyroid hormone function in adolescence. Additionally, we explored how exposure to BPA during two specific periods influenced changes in thyroid hormone levels.The study observed that urinary BPA levels at ages 3-5 years were not notably linked to thyroid hormone levels in adolescents aged 10-12 years. However, BPA levels at ages 7-9 years were significantly associated with free T3 levels in girls aged 10-12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations.RESULTSThe study observed that urinary BPA levels at ages 3-5 years were not notably linked to thyroid hormone levels in adolescents aged 10-12 years. However, BPA levels at ages 7-9 years were significantly associated with free T3 levels in girls aged 10-12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations.BPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.CONCLUSIONSBPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.
Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea. The study observed that urinary BPA levels at ages 3-5 years were not notably linked to thyroid hormone levels in adolescents aged 10-12 years. However, BPA levels at ages 7-9 years were significantly associated with free T3 levels in girls aged 10-12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations. BPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.
Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea. Participants were drawn from the Ewha Birth and Growth Cohort Study, encompassing individuals who visited Ewha Women's Mokdong Hospital between 2001 and 2005. The concentration of urinary BPA was repeatedly measured for each subject at ages 3-5 years and 7-9 years. Serum levels of free triiothyronine (T3), free thyroxine (T4), and thyroid-stimulating hormone (TSH) were measured at ages 10-12 years in a subgroup of 128 out of 164 subjects who had undergone repeated BPA concentration measurements. We utilized the SAS program to analyze possible links between childhood exposure to BPA and thyroid hormone function in adolescence. Additionally, we explored how exposure to BPA during two specific periods influenced changes in thyroid hormone levels. The study observed that urinary BPA levels at ages 3-5 years were not notably linked to thyroid hormone levels in adolescents aged 10-12 years. However, BPA levels at ages 7-9 years were significantly associated with free T3 levels in girls aged 10-12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations. BPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.
Background Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea. Methods Participants were drawn from the Ewha Birth and Growth Cohort Study, encompassing individuals who visited Ewha Women’s Mokdong Hospital between 2001 and 2005. The concentration of urinary BPA was repeatedly measured for each subject at ages 3–5 years and 7–9 years. Serum levels of free triiothyronine (T3), free thyroxine (T4), and thyroid-stimulating hormone (TSH) were measured at ages 10–12 years in a subgroup of 128 out of 164 subjects who had undergone repeated BPA concentration measurements. We utilized the SAS program to analyze possible links between childhood exposure to BPA and thyroid hormone function in adolescence. Additionally, we explored how exposure to BPA during two specific periods influenced changes in thyroid hormone levels. Results The study observed that urinary BPA levels at ages 3–5 years were not notably linked to thyroid hormone levels in adolescents aged 10–12 years. However, BPA levels at ages 7–9 years were significantly associated with free T3 levels in girls aged 10–12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations. Conclusions BPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.
Background Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea. Methods Participants were drawn from the Ewha Birth and Growth Cohort Study, encompassing individuals who visited Ewha Women's Mokdong Hospital between 2001 and 2005. The concentration of urinary BPA was repeatedly measured for each subject at ages 3-5 years and 7-9 years. Serum levels of free triiothyronine (T3), free thyroxine (T4), and thyroid-stimulating hormone (TSH) were measured at ages 10-12 years in a subgroup of 128 out of 164 subjects who had undergone repeated BPA concentration measurements. We utilized the SAS program to analyze possible links between childhood exposure to BPA and thyroid hormone function in adolescence. Additionally, we explored how exposure to BPA during two specific periods influenced changes in thyroid hormone levels. Results The study observed that urinary BPA levels at ages 3-5 years were not notably linked to thyroid hormone levels in adolescents aged 10-12 years. However, BPA levels at ages 7-9 years were significantly associated with free T3 levels in girls aged 10-12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations. Conclusions BPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.
BackgroundBisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits weak estrogenic and potent anti-androgenic effects, and prior research has linked it to disturbances in thyroid function. This study aims to assess the potential association between early childhood exposure to urinary bisphenol A and thyroid hormone levels in pubertal children from Korea.MethodsParticipants were drawn from the Ewha Birth and Growth Cohort Study, encompassing individuals who visited Ewha Women's Mokdong Hospital between 2001 and 2005. The concentration of urinary BPA was repeatedly measured for each subject at ages 3-5 years and 7-9 years. Serum levels of free triiothyronine (T3), free thyroxine (T4), and thyroid-stimulating hormone (TSH) were measured at ages 10-12 years in a subgroup of 128 out of 164 subjects who had undergone repeated BPA concentration measurements. We utilized the SAS program to analyze possible links between childhood exposure to BPA and thyroid hormone function in adolescence. Additionally, we explored how exposure to BPA during two specific periods influenced changes in thyroid hormone levels.ResultsThe study observed that urinary BPA levels at ages 3-5 years were not notably linked to thyroid hormone levels in adolescents aged 10-12 years. However, BPA levels at ages 7-9 years were significantly associated with free T3 levels in girls aged 10-12 years. Conversely, exposure to BPA did not result in significant differences in thyroid hormone levels among boys. The study did not find statistically significant connections between levels of urinary BPA and the other thyroid hormones, specifically TSH and free T4. There was a significant decrease in the concentration of free T3 in girls with higher BPA concentrations.ConclusionsBPA exposure in childhood affects thyroid function in adolescent girls. This relationship may contribute to an increased prevalence of thyroid disorders in adolescents due to environmental influences.
Audience Academic
Author Kim, Hae Soon
Choi, Jung Eun
Ha, Eunhee
Park, Bohyun
Lee, Seonhwa
Hong, Young Sun
Park, Hyesook
Lee, Hye Ah
Choi, Eun Jeong
AuthorAffiliation King Faisal Specialist Hospital and Research Center, SAUDI ARABIA
3 National Cancer Control Institute, National Cancer Center, Goyang, Korea
7 Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, Republic of Korea
4 Clinical Trial Center, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea
1 Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul Hospital, Seoul, Republic of Korea
2 Department of Preventive Medicine, College of Medicine, Ewha Womans University, Seoul, Korea
5 Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea
6 Department of Occupational and Environmental Medicine, College of Medicine, Ewha Womans University, Seoul, Korea
AuthorAffiliation_xml – name: 1 Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul Hospital, Seoul, Republic of Korea
– name: 4 Clinical Trial Center, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea
– name: 7 Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, Republic of Korea
– name: 3 National Cancer Control Institute, National Cancer Center, Goyang, Korea
– name: 6 Department of Occupational and Environmental Medicine, College of Medicine, Ewha Womans University, Seoul, Korea
– name: King Faisal Specialist Hospital and Research Center, SAUDI ARABIA
– name: 5 Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea
– name: 2 Department of Preventive Medicine, College of Medicine, Ewha Womans University, Seoul, Korea
Author_xml – sequence: 1
  givenname: Jung Eun
  orcidid: 0000-0001-8956-4192
  surname: Choi
  fullname: Choi, Jung Eun
– sequence: 2
  givenname: Eun Jeong
  surname: Choi
  fullname: Choi, Eun Jeong
– sequence: 3
  givenname: Seonhwa
  surname: Lee
  fullname: Lee, Seonhwa
– sequence: 4
  givenname: Bohyun
  surname: Park
  fullname: Park, Bohyun
– sequence: 5
  givenname: Hye Ah
  surname: Lee
  fullname: Lee, Hye Ah
– sequence: 6
  givenname: Young Sun
  surname: Hong
  fullname: Hong, Young Sun
– sequence: 7
  givenname: Eunhee
  surname: Ha
  fullname: Ha, Eunhee
– sequence: 8
  givenname: Hae Soon
  orcidid: 0000-0002-6976-6878
  surname: Kim
  fullname: Kim, Hae Soon
– sequence: 9
  givenname: Hyesook
  surname: Park
  fullname: Park, Hyesook
BackLink https://www.ncbi.nlm.nih.gov/pubmed/40403006$$D View this record in MEDLINE/PubMed
BookMark eNqNk1tr2zAYhs3oWNts_2BsgsHYLpLpYMvybkYoOwQKhe5wK3RyrE6RMskey7-f3KQlHr0YvrD59Oj99L7Wd16c-OBNUTxHcIFIjd7dhCF64RbbXF5AgjGt2KPiDDUEzymG5OTo-7Q4T-kGwoowSp8UpyUsIYGQnhU_r40TvQ0-dXYLQguGaL2IOyBt2nbGBweWwHqgOut0F4IGwYO-28VgNehC3OTuoB28GjVGUOjgTFLG9-k9EECFDPUg9YPePS0et8Il8-zwnhXfP338dvFlfnn1eXWxvJwrWpb9XOJGUtwy2ujKSMk0pYIYwaTCDZOYIVRXumZKGtJkz7qELYEUY9hS3SCmyax4udfdupD4IafECYaUEcTqMhOrPaGDuOHbaDfZMg_C8ttCiGsuYm-VM1xqo_NhBCGMlbo2gjJlUCWkNLSqc8Kz4sOh2yA3Ro_Oo3AT0emKtx1fh98cYdjUVQWzwpuDQgy_BpN6vrE5QeeEN2HYH7xhJcEko6_-QR-2d6DWIjuwvg25sRpF-ZKVY1fGUKYWD1D50WZjVf6vrc31yYa3kw2Z6c2ffi2GlPjq6_X_s1c_puzrI7YzwvVdCm64vZZT8MVx1PcZ313nDJR7QMWQUjTtPYIgH6fmLi4-Tg0_TA35C0uBCec
Cites_doi 10.1289/ehp.10753
10.3389/fendo.2024.1420540
10.1186/s12940-022-00953-w
10.1016/j.reprotox.2007.05.010
10.1016/j.envint.2019.105123
10.1097/MD.0000000000023067
10.3961/jpmph.20.310
10.3390/ijerph14020123
10.3803/EnM.2019.34.4.340
10.3390/ijerph17082654
10.1289/ehp.9804
10.1371/journal.pone.0141248
10.3389/fendo.2021.653680
10.1016/j.envres.2017.11.007
10.1210/jc.2002-020209
10.1016/j.mce.2011.09.005
10.1016/j.envres.2015.03.003
10.3390/nu14010168
10.1016/j.scitotenv.2020.137887
10.1016/j.envint.2017.05.007
10.1289/ehp.1408989
10.1016/j.envint.2020.105782
10.3390/ijms22126521
10.1006/bbrc.2002.6407
10.1089/thy.2018.0051
10.1016/j.bbrc.2004.10.073
ContentType Journal Article
Copyright Copyright: © 2025 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
COPYRIGHT 2025 Public Library of Science
2025 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2025 Choi et al 2025 Choi et al
2025 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: Copyright: © 2025 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
– notice: COPYRIGHT 2025 Public Library of Science
– notice: 2025 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2025 Choi et al 2025 Choi et al
– notice: 2025 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
IOV
ISR
3V.
7QG
7QL
7QO
7RV
7SN
7SS
7T5
7TG
7TM
7U9
7X2
7X7
7XB
88E
8AO
8C1
8FD
8FE
8FG
8FH
8FI
8FJ
8FK
ABJCF
ABUWG
AEUYN
AFKRA
ARAPS
ATCPS
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
C1K
CCPQU
D1I
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
KB.
KB0
KL.
L6V
LK8
M0K
M0S
M1P
M7N
M7P
M7S
NAPCQ
P5Z
P62
P64
PATMY
PDBOC
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
PTHSS
PYCSY
RC3
7X8
5PM
DOA
DOI 10.1371/journal.pone.0322658
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Gale In Context: Opposing Viewpoints
Gale In Context: Science
ProQuest Central (Corporate)
Animal Behavior Abstracts
Bacteriology Abstracts (Microbiology B)
Biotechnology Research Abstracts
Nursing & Allied Health Database
Ecology Abstracts
Entomology Abstracts (Full archive)
Immunology Abstracts
Meteorological & Geoastrophysical Abstracts
Nucleic Acids Abstracts
Virology and AIDS Abstracts
Agricultural Science Collection
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
Public Health Database
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
Materials Science & Engineering Collection
ProQuest Central (Alumni)
ProQuest One Sustainability
ProQuest Central UK/Ireland
Advanced Technologies & Aerospace Collection
Agricultural & Environmental Science Collection
ProQuest Central Essentials
Biological Science Collection
Text complet a ProQuest Central
Technology Collection
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Materials Science Collection
ProQuest Central Korea
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Materials Science Database
Nursing & Allied Health Database (Alumni Edition)
Meteorological & Geoastrophysical Abstracts - Academic
ProQuest Engineering Collection
Biological Sciences
Agriculture Science Database
ProQuest Health & Medical Collection
Medical Database
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Engineering Database
Nursing & Allied Health Premium
Advanced Technologies & Aerospace Database
ProQuest Advanced Technologies & Aerospace Collection
Biotechnology and BioEngineering Abstracts
Environmental Science Database
Materials Science Collection
ProQuest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
Engineering Collection
Environmental Science Collection
Genetics Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Agricultural Science Database
Publicly Available Content Database
ProQuest Central Student
ProQuest Advanced Technologies & Aerospace Collection
ProQuest Central Essentials
Nucleic Acids Abstracts
SciTech Premium Collection
Environmental Sciences and Pollution Management
ProQuest One Applied & Life Sciences
ProQuest One Sustainability
Health Research Premium Collection
Meteorological & Geoastrophysical Abstracts
Natural Science Collection
Health & Medical Research Collection
Biological Science Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
Engineering Collection
Advanced Technologies & Aerospace Collection
Engineering Database
Virology and AIDS Abstracts
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
Agricultural Science Collection
ProQuest Hospital Collection
ProQuest Technology Collection
Health Research Premium Collection (Alumni)
Biological Science Database
Ecology Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Environmental Science Collection
Entomology Abstracts
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Environmental Science Database
ProQuest Nursing & Allied Health Source (Alumni)
Engineering Research Database
ProQuest One Academic
Meteorological & Geoastrophysical Abstracts - Academic
ProQuest One Academic (New)
Technology Collection
Technology Research Database
ProQuest One Academic Middle East (New)
Materials Science Collection
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central
ProQuest Health & Medical Research Collection
Genetics Abstracts
ProQuest Engineering Collection
Biotechnology Research Abstracts
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Agricultural & Environmental Science Collection
AIDS and Cancer Research Abstracts
Materials Science Database
ProQuest Materials Science Collection
ProQuest Public Health
ProQuest Nursing & Allied Health Source
ProQuest SciTech Collection
Advanced Technologies & Aerospace Database
ProQuest Medical Library
Animal Behavior Abstracts
Materials Science & Engineering Collection
Immunology Abstracts
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic

MEDLINE




Agricultural Science Database
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: 8FG
  name: ProQuest Technology Collection
  url: https://search.proquest.com/technologycollection1
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Sciences (General)
Education
DocumentTitleAlternate Urinary BPA and Thyroid Function in Adolescents: A Cohort Study
EISSN 1932-6203
ExternalDocumentID 3206831874
oai_doaj_org_article_bded2f8a33884d7ea68ce15abbe65719
PMC12097550
A840975881
40403006
10_1371_journal_pone_0322658
Genre Journal Article
GeographicLocations South Korea
United States--US
GeographicLocations_xml – name: South Korea
– name: United States--US
GroupedDBID ---
123
29O
2WC
53G
5VS
7RV
7X2
7X7
7XC
88E
8AO
8C1
8CJ
8FE
8FG
8FH
8FI
8FJ
A8Z
AAFWJ
AAUCC
AAWOE
AAYXX
ABDBF
ABIVO
ABJCF
ABUWG
ACGFO
ACIHN
ACIWK
ACPRK
ACUHS
ADBBV
AEAQA
AENEX
AEUYN
AFKRA
AFPKN
AFRAH
AHMBA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
APEBS
ARAPS
ATCPS
BAWUL
BBNVY
BCNDV
BENPR
BGLVJ
BHPHI
BKEYQ
BPHCQ
BVXVI
BWKFM
CCPQU
CITATION
CS3
D1I
D1J
D1K
DIK
DU5
E3Z
EAP
EAS
EBD
EMOBN
ESX
EX3
F5P
FPL
FYUFA
GROUPED_DOAJ
GX1
HCIFZ
HH5
HMCUK
HYE
IAO
IEA
IGS
IHR
IHW
INH
INR
IOV
IPY
ISE
ISR
ITC
K6-
KB.
KQ8
L6V
LK5
LK8
M0K
M1P
M48
M7P
M7R
M7S
M~E
NAPCQ
O5R
O5S
OK1
OVT
P2P
P62
PATMY
PDBOC
PHGZM
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
PTHSS
PV9
PYCSY
RNS
RPM
RZL
SV3
TR2
UKHRP
WOQ
WOW
~02
~KM
ADRAZ
BBORY
CGR
CUY
CVF
ECM
EIF
IPNFZ
NPM
RIG
PMFND
3V.
7QG
7QL
7QO
7SN
7SS
7T5
7TG
7TM
7U9
7XB
8FD
8FK
AZQEC
C1K
DWQXO
FR3
GNUQQ
H94
K9.
KL.
M7N
P64
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQUKI
RC3
7X8
5PM
PUEGO
ID FETCH-LOGICAL-c644t-b29b62f869d5ebb8d66a3ea8bc298b281175d78cbe39658d40f306220f6d918d3
IEDL.DBID M48
ISSN 1932-6203
IngestDate Fri Aug 22 23:50:16 EDT 2025
Wed Aug 27 01:24:30 EDT 2025
Thu Aug 21 18:30:09 EDT 2025
Fri Jul 11 17:20:02 EDT 2025
Fri Jul 25 09:46:43 EDT 2025
Tue Jun 17 21:56:10 EDT 2025
Tue Jun 10 21:08:02 EDT 2025
Fri Jun 27 05:15:53 EDT 2025
Fri Jun 27 05:16:01 EDT 2025
Tue Jun 03 02:17:40 EDT 2025
Mon May 26 01:57:47 EDT 2025
Sun Jul 06 05:03:26 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 5
Language English
License Copyright: © 2025 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Creative Commons Attribution License
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c644t-b29b62f869d5ebb8d66a3ea8bc298b281175d78cbe39658d40f306220f6d918d3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
HK and HP also contributed equally to this work.
Competing Interests: The authors have declared that no competing interests exist.
ORCID 0000-0001-8956-4192
0000-0002-6976-6878
OpenAccessLink http://journals.scholarsportal.info/openUrl.xqy?doi=10.1371/journal.pone.0322658
PMID 40403006
PQID 3206831874
PQPubID 1436336
PageCount e0322658
ParticipantIDs plos_journals_3206831874
doaj_primary_oai_doaj_org_article_bded2f8a33884d7ea68ce15abbe65719
pubmedcentral_primary_oai_pubmedcentral_nih_gov_12097550
proquest_miscellaneous_3206984323
proquest_journals_3206831874
gale_infotracmisc_A840975881
gale_infotracacademiconefile_A840975881
gale_incontextgauss_ISR_A840975881
gale_incontextgauss_IOV_A840975881
gale_healthsolutions_A840975881
pubmed_primary_40403006
crossref_primary_10_1371_journal_pone_0322658
PublicationCentury 2000
PublicationDate 20250522
PublicationDateYYYYMMDD 2025-05-22
PublicationDate_xml – month: 5
  year: 2025
  text: 20250522
  day: 22
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: San Francisco
– name: San Francisco, CA USA
PublicationTitle PloS one
PublicationTitleAlternate PLoS One
PublicationYear 2025
Publisher Public Library of Science
Public Library of Science (PLoS)
Publisher_xml – name: Public Library of Science
– name: Public Library of Science (PLoS)
References N Wang (pone.0322658.ref020) 2015; 10
T Takeuchi (pone.0322658.ref030) 2004; 325
JR Rochester (pone.0322658.ref004) 2015; 123
Y Wang (pone.0322658.ref012) 2021; 12
G Weber (pone.0322658.ref028) 2003
D Koutaki (pone.0322658.ref011) 2021; 14
M-T Wu (pone.0322658.ref032) 2013; 8
TI Weng (pone.0322658.ref025) 2017; 14
F Gorini (pone.0322658.ref010) 2020; 17
C Park (pone.0322658.ref017) 2017
S Lee (pone.0322658.ref015) 2018; 161
MJ Kim (pone.0322658.ref026) 2019; 29
AM Calafat (pone.0322658.ref013) 2008; 116
J Liu (pone.0322658.ref008) 2024; 15
K Moriyama (pone.0322658.ref021) 2002; 87
ME Romano (pone.0322658.ref009) 2015; 138
JA Kwon (pone.0322658.ref019) 2020; 240
N Yuan (pone.0322658.ref033) 2020; 99
K-N Kim (pone.0322658.ref024) 2020; 141
CA Richter (pone.0322658.ref022) 2007; 115
M Babić Leko (pone.0322658.ref002) 2021; 22
MJ Kim (pone.0322658.ref001) 2019; 34
A Derakhshan (pone.0322658.ref007) 2019; 133
HA Lee (pone.0322658.ref014) 2021; 43
S Lee (pone.0322658.ref016) 2023; 22
K Mikołajewska (pone.0322658.ref027) 2015; 28
K. Sadek (pone.0322658.ref031) 2014; 8
F Li (pone.0322658.ref018) 2020; 722
Y Jang (pone.0322658.ref003) 2021; 54
T Takeuchi (pone.0322658.ref029) 2002; 291
R Morgenstern (pone.0322658.ref023); 106
YB Wetherill (pone.0322658.ref005) 2007; 24
M Boas (pone.0322658.ref006) 2012; 355
References_xml – volume: 116
  start-page: 39
  issue: 1
  year: 2008
  ident: pone.0322658.ref013
  article-title: Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.10753
– volume: 240
  start-page: 125187
  year: 2020
  ident: pone.0322658.ref019
  article-title: Urinary bisphenol A and thyroid function by BMI in the Korean National Environmental Health Survey (KoNEHS) 2012-2014
  publication-title: Chemosphere
– volume: 15
  start-page: 1420540
  year: 2024
  ident: pone.0322658.ref008
  article-title: Maternal bisphenols exposure and thyroid function in children: a systematic review and meta-analysis
  publication-title: Front Endocrinol (Lausanne)
  doi: 10.3389/fendo.2024.1420540
– volume: 22
  start-page: 3
  issue: 1
  year: 2023
  ident: pone.0322658.ref016
  article-title: Prospective association between phthalate exposure in childhood and liver function in adolescence: the Ewha Birth and Growth Cohort Study
  publication-title: Environ Health
  doi: 10.1186/s12940-022-00953-w
– volume: 24
  start-page: 178
  issue: 2
  year: 2007
  ident: pone.0322658.ref005
  article-title: In vitro molecular mechanisms of bisphenol A action
  publication-title: Reprod Toxicol
  doi: 10.1016/j.reprotox.2007.05.010
– volume: 133
  start-page: 105123
  year: 2019
  ident: pone.0322658.ref007
  article-title: Association of urinary bisphenols and triclosan with thyroid function during early pregnancy
  publication-title: Environ Int
  doi: 10.1016/j.envint.2019.105123
– volume: 99
  issue: 45
  year: 2020
  ident: pone.0322658.ref033
  article-title: Bisphenol A and thyroid hormones: Bibliometric analysis of scientific publications
  publication-title: Medicine (Baltimore)
  doi: 10.1097/MD.0000000000023067
– volume: 54
  start-page: 37
  issue: 1
  year: 2021
  ident: pone.0322658.ref003
  article-title: Associations between thyroid hormone levels and urinary concentrations of bisphenol A, F, and S in 6-year-old children in Korea
  publication-title: J Prev Med Public Health
  doi: 10.3961/jpmph.20.310
– volume: 14
  start-page: 123
  issue: 2
  year: 2017
  ident: pone.0322658.ref025
  article-title: Effects of gender on the association of urinary phthalate metabolites with thyroid hormones in children: A prospective cohort study in Taiwan
  publication-title: Int J Environ Res Public Health
  doi: 10.3390/ijerph14020123
– start-page: 253
  year: 2003
  ident: pone.0322658.ref028
  article-title: Thyroid function and puberty
  publication-title: J Pediatr Endocrinol Metab
– year: 2017
  ident: pone.0322658.ref017
  article-title: Associations between urinary phthalate metabolites and bisphenol A levels and serum thyroid hormones among the Korean adult population - Korean National Environmental Health Survey (KoNEHS) 2012–2014.
  publication-title: Sci Total Environ
– volume: 34
  start-page: 340
  issue: 4
  year: 2019
  ident: pone.0322658.ref001
  article-title: Bisphenols and thyroid hormone
  publication-title: Endocrinol Metab (Seoul)
  doi: 10.3803/EnM.2019.34.4.340
– volume: 17
  start-page: 2654
  issue: 8
  year: 2020
  ident: pone.0322658.ref010
  article-title: Bisphenols as environmental triggers of thyroid dysfunction: Clues and evidence
  publication-title: Int J Environ Res Public Health
  doi: 10.3390/ijerph17082654
– volume: 115
  start-page: 902
  issue: 6
  year: 2007
  ident: pone.0322658.ref022
  article-title: Estradiol and Bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate mesenchyme cells
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.9804
– volume: 10
  issue: 10
  year: 2015
  ident: pone.0322658.ref020
  article-title: Influence of Bisphenol A on Thyroid Volume and Structure Independent of Iodine in School Children
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0141248
– volume: 12
  start-page: 653680
  year: 2021
  ident: pone.0322658.ref012
  article-title: Thyroid function changes and pubertal progress in females: A longitudinal study in iodine-sufficient areas of East China
  publication-title: Front Endocrinol (Lausanne)
  doi: 10.3389/fendo.2021.653680
– volume: 43
  year: 2021
  ident: pone.0322658.ref014
  article-title: Cohort profile: The Ewha birth and growth study
  publication-title: Epidemiol Health
– volume: 161
  start-page: 195
  year: 2018
  ident: pone.0322658.ref015
  article-title: A prospective cohort study of the association between bisphenol A exposure and the serum levels of liver enzymes in children
  publication-title: Environ Res
  doi: 10.1016/j.envres.2017.11.007
– volume: 87
  start-page: 5185
  issue: 11
  year: 2002
  ident: pone.0322658.ref021
  article-title: Thyroid hormone action is disrupted by bisphenol A as an antagonist
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2002-020209
– volume: 8
  issue: 11
  year: 2014
  ident: pone.0322658.ref031
  article-title: Oxidative and hormonal disruptions underlie bisphenol A – Induced testicular toxicity in male rabbits
  publication-title: International Science Index
– volume: 8
  issue: 1
  year: 2013
  ident: pone.0322658.ref032
  article-title: Intake of phthalate-tainted foods alters thyroid functions in Taiwanese children
  publication-title: PLoS One
– volume: 355
  start-page: 240
  issue: 2
  year: 2012
  ident: pone.0322658.ref006
  article-title: Thyroid effects of endocrine disrupting chemicals
  publication-title: Mol Cell Endocrinol
  doi: 10.1016/j.mce.2011.09.005
– volume: 138
  start-page: 453
  year: 2015
  ident: pone.0322658.ref009
  article-title: Gestational urinary bisphenol A and maternal and newborn thyroid hormone concentrations: the HOME Study
  publication-title: Environ Res
  doi: 10.1016/j.envres.2015.03.003
– volume: 14
  start-page: 168
  issue: 1
  year: 2021
  ident: pone.0322658.ref011
  article-title: The impact of bisphenol A on thyroid function in neonates and children: A systematic review of the literature
  publication-title: Nutrients
  doi: 10.3390/nu14010168
– volume: 722
  start-page: 137887
  year: 2020
  ident: pone.0322658.ref018
  article-title: Prenatal bisphenol A exposure, fetal thyroid hormones and neurobehavioral development in children at 2 and 4 years: A prospective cohort study
  publication-title: Sci Total Environ
  doi: 10.1016/j.scitotenv.2020.137887
– volume: 106
  start-page: 11
  ident: pone.0322658.ref023
  article-title: Phthalates and thyroid function in preschool age children: Sex specific associations
  publication-title: Environ. Int
  doi: 10.1016/j.envint.2017.05.007
– volume: 123
  start-page: 643
  issue: 7
  year: 2015
  ident: pone.0322658.ref004
  article-title: Bisphenol S and F: A systematic review and comparison of the hormonal activity of bisphenol A substitutes
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1408989
– volume: 141
  start-page: 105782
  year: 2020
  ident: pone.0322658.ref024
  article-title: Prenatal and early childhood phthalate exposures and thyroid function among school-age children
  publication-title: Environ Int
  doi: 10.1016/j.envint.2020.105782
– volume: 22
  start-page: 6521
  issue: 12
  year: 2021
  ident: pone.0322658.ref002
  article-title: Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels
  publication-title: Int J Mol Sci
  doi: 10.3390/ijms22126521
– volume: 291
  start-page: 76
  issue: 1
  year: 2002
  ident: pone.0322658.ref029
  article-title: Serum bisphenol a concentrations showed gender differences, possibly linked to androgen levels
  publication-title: Biochem Biophys Res Commun
  doi: 10.1006/bbrc.2002.6407
– volume: 29
  start-page: 183
  issue: 2
  year: 2019
  ident: pone.0322658.ref026
  article-title: Association between diethylhexyl phthalate exposure and thyroid function: A meta-analysis
  publication-title: Thyroid
  doi: 10.1089/thy.2018.0051
– volume: 325
  start-page: 549
  issue: 2
  year: 2004
  ident: pone.0322658.ref030
  article-title: Gender difference in serum bisphenol A levels may be caused by liver UDP-glucuronosyltransferase activity in rats
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/j.bbrc.2004.10.073
– volume: 28
  start-page: 209
  issue: 2
  year: 2015
  ident: pone.0322658.ref027
  article-title: Bisphenol A - Application, sources of exposure and potential risks in infants, children and pregnant women
  publication-title: Int J Occup Med Environ Health
SSID ssj0053866
Score 2.4758677
Snippet Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA exhibits...
Background Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers....
BackgroundBisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers. BPA...
Background Bisphenol A (BPA) is a type of endocrine-disrupting chemical utilized in the production of plastics like epoxy resins and polycarbonate polymers....
SourceID plos
doaj
pubmedcentral
proquest
gale
pubmed
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage e0322658
SubjectTerms Adolescent
Adolescents
Age
Benzhydryl Compounds - urine
Biology and Life Sciences
Bisphenol A
Bisphenol A Compounds
Body mass index
Child
Child, Preschool
Childhood
Children
Children & youth
Cohort analysis
Cohort Studies
Creatinine
Demographic aspects
Ecology and Environmental Sciences
Education
Endocrine disruptors
Endocrine Disruptors - urine
Environmental Exposure
Epoxy resins
Exposure
Female
Food
Generalized linear models
Girls
Health aspects
Hormones
Humans
Immunoassay
Male
Mass spectrometry
Measurement
Medical examination
Medicine and Health Sciences
Normal distribution
People and Places
Phenols - urine
Physical Sciences
Polycarbonate
Polymers
Regression analysis
Research and Analysis Methods
Scientific imaging
Serum levels
Social Sciences
Statistical analysis
Subgroups
Teenage girls
Thyroid
Thyroid diseases
Thyroid gland
Thyroid gland function tests
Thyroid hormones
Thyroid Hormones - blood
Thyroid-stimulating hormone
Thyrotropin - blood
Thyroxine
Thyroxine - blood
Tobacco smoke
Trends
Triiodothyronine
Triiodothyronine - blood
Xenoestrogens
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELbQnnpBlAINlGIQEnBwm9iJ4_RWEFVBAiSgqDfLjh02AiWrze6Bf89M4kQbVAkOXOPJKJmHPZPMfEPI86xwtvKlYE5YxyD-t6woTMy8l16q0pbW4_eODx_l5VX6_jq73hn1hTVhAzzwILhT67zjlTKQSqnU5d4AB59kxlovs7wH_ORw5o3J1LAHgxdLGRrlRJ6cBr2crNrGn8RgwxJHvO8cRD1e_7QrL1Y_2-6mkPPPysmdo-jiDrkdYkh6Pjz7Prnlm7tkP3hpR18GKOlXB-THVOu2rFe0rSh-WzfrX9TWHRZ3tcCF1g0tR4Bj2jYUVLdua0eXEM7Cm1A8-pAHEu4AQJ1RQ3G87npDe4zae-Tq4u3XN5csjFdgJQRBG2Z5YSWIVhYu89YqJ6UR3ihb8kJZjh2omctBX14gQoxL4wryC87jSroiUU7cJ4sGHuOQUAGc0qSyFcQXqUmAo_NJJfI4L7mXRRoRNsparwYUDd3_Sssh-xiEplE3OugmIq9RIRMtYmD3F8AydLAM_TfLiMgTVKceGkonT9bnmNNCmqSSiDzrKRAHo8FCm-9m23X63adv_0D05fOM6EUgqlowjNKE5gZ4J8TXmlEezSjBm8vZ8iEa3yiVTgseSyVwciLcORrkzctPp2VkisVzjW-3A02hUsFFRB4M9jtJNoVNXMDOGxE1s-yZ6OcrTb3sYcix6zqHBPfh_1DWI7LHcbJynDHOj8his976xxDubexx79m_AVcsVo4
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Health & Medical Collection
  dbid: 7X7
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3Nj5UwEG_0efFi3PVj0VWrMVEP7EILpfViVuNmNVETdc27kZaWfUQDCO8d_O-dgT58mI3xSodJ6Xx0pkx_Q8jTVFlTuoKHlhsbQvxvQqV0FDonnJCFKYzD844PH8XZefJ-mS79gVvvyyq3PnFw1LYp8Iz8mLNISI4d5F61P0PsGoV_V30LjavkGkKXYUlXtpwSLrBlIfx1OZ7Fx146R21Tu6MINFlgo_ed7WhA7Z9886L90fSXBZ5_10_ubEinN8kNH0nSk1H0e-SKq_exCbMv2Ngne95ue_rcg0u_uEW-T9Vvq6qlTUnxtF13v6ipeiz3aoAjrWpabCGPaVNTEGbXVJauIMCFr6K4GSIPJNyBhHpJNcWGu92aDqi1t8n56duvb85C33AhLCAsWoeGKSNYKYWyqTNGWiE0d1qagilpGN5JTW0GEnQcMWNsEpWQcTAWlcKqWFp-hyxqmMYBoRw4JXFpSog4Eh0DR-vikmdRVjAnVBKQcLvueTviauTDz7UM8pFxAXOUU-7lFJDXKJyJFlGxhwdNd5F7I8uNdRamryHtlonNnAZtc3GqjXEizWIVkEco2ny8YjrZdn6CWS4kTjIOyJOBApExaiy9udCbvs_fffr2H0RfPs-InnmisgElKbS_7gDfhIhbM8rDGSXYdzEbPkBF3K5Kn_-xBHhzq5yXDz-ehpEpltPVrtmMNEomnPGA3B11eVrZBNw6B18cEDnT8tnSz0fqajUAk-M97AxS3nv_ntd9cp1hF-UoDRk7JIt1t3EPILRbm4eD_f4Gb4FQew
  priority: 102
  providerName: ProQuest
Title Relationship of urinary bisphenol A in childhood on thyroid hormone function in adolescents: a cohort study
URI https://www.ncbi.nlm.nih.gov/pubmed/40403006
https://www.proquest.com/docview/3206831874
https://www.proquest.com/docview/3206984323
https://pubmed.ncbi.nlm.nih.gov/PMC12097550
https://doaj.org/article/bded2f8a33884d7ea68ce15abbe65719
http://dx.doi.org/10.1371/journal.pone.0322658
Volume 20
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELe27oUXxPhaYBSDkICHVImdOA4SQtvUMpA20KCob1EcO2vElJSkldgLfzt3-dKCirQXP9SXa3If9p0_fkfIKz_UKjUJtzVX2ob4X9lhGDu2McIImahEGVzvODsXp3Pv88Jf7JCuZmsrwGpraof1pObl1eT3r-sP4PDv66oNgds9NFkVuZk4YKEwq-6SPZibAnTVM6_fVwDvrncvMWqxBXN4e5nuf1wGk1WN6d-P3KPVVVFtC0v_PV15Y7qa3SN32ziTHjWGsU92TH6f7LeeXNE3Ldz02wfkZ38ebpmtaJFSXH-Py2uqsgoPgBXAhWY5TToQZFrkFNRbFpmmSwh54UsoTo_IAwlvgES9ozHFErzlmtY4tg_JfDb9fnJqtyUY7AQCpbWtWKgES6UItW-UklqImJtYqoSFUjG8perrAHRqOKLIaM9JIQdhzEmFDl2p-SMyyuE1DgjlwMlzU5VCDOLFLnDUxk154AQJMyL0LGJ3so5WDdJGVG-3BZChNEKLUDdRqxuLHKNCelrEya5_KMrLqHW7SGmj4fVjSMSlpwMTg_0Z14-VMsIP3NAiz1GdUXPptPf26AjzXkilpGuRlzUFYmXkeBjnMt5UVfTpy49bEH27GBC9bonSAgwjidsLEPBNiME1oDwcUILHJ4PuAzS-TipVxJkjJMfqivBkZ5Dbu1_03cgUD9jlptg0NKH0OOMWedzYby9ZDwZ6DqOzReTAsgeiH_bk2bKGKseb2QEkwU9u8cdPyR2GxZUd32bskIzW5cY8g4hvrcZkN1gE0MoTF9vZxzHZO56ef70Y12so49rJsf0z_Qs53lzN
linkProvider Scholars Portal
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtR3LbtQw0CrLAS6IlkcDhRoEAg5pEztxEiSEyqPapQ8kaNHeTBw73RUoWTa7Qv0pvpGZxAkbVCEuvcaTkTMznoczD0KehIlWucm4q7nSLvj_yk2S1HONEUbEmcqUwfuOo2MxPA0-jMPxGvnV1sJgWmWrE2tFrcsM78h3OfNEzHGC3OvZDxenRuHf1XaERiMWB-b8J4Rs1avRO-DvU8b235-8Hbp2qoCbge1fuIolSrA8FokOjVKxFiLlJo1VxpJYMSy8DHUE2zQcG6PowMvBrWbMy4VO_FhzwHuFXAXD6-GJisZdgAe6Qwhbnscjf9dKw86sLMyOBydH4GD5FfNXTwnobMFg9r2sLnJ0_87XXDGA-zfJDeu50r1G1NbJmik2cOizTRDZIOtWT1T0uW1m_eIW-dZl202mM1rmFG_30_k5VdMK08tKwEinBc3aFsu0LCgIz7ycajoBhxq-iqLxRRwIuNKC6iVNKQ74nS9o3SX3Njm9FFbcIYMCtrFJKAdMgZ-rHDycIPUBozZ-ziMvypgRSeAQt6W7nDV9PGT9My-C-KchoEQ-Scsnh7xB5nSw2IW7flDOz6Q91FJpo2H7KYT5caAjk4J0Gz9MlTIijPzEIdvIWtmUtHa6RO5hVA2BWuw75HENgZ04Ckz1OUuXVSVHH7_8B9DnTz2gZxYoL0FIstSWV8A3YYevHuRWDxL0SdZb3kRBbKlSyT8nD95shfPi5UfdMiLF9L3ClMsGJokDzrhD7jay3FE2ADPCQfc7JO5JeY_0_ZViOqkboWPddwQh9r1_72ubXBueHB3Kw9HxwX1yneEEZy90Gdsig8V8aR6AW7lQD-uzTMnXy1YevwHv_4zy
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELdGkRAviI2PBQYzCAQ8ZE3sxEmQEBqMaWUwEGOobyaOnbUCJaVphfav8ddxlzihQRPiZa_19eT4fr6P5D4IeRQmWuUm467mSrvg_ys3SVLPNUYYEWcqUwbfd7w_EgcnwdtxOF4jv9paGEyrbHVirah1meE78iFnnog5TpAb5jYt4uPe_svZDxcnSOGX1nacRgORQ3P2E8K36sVoD2T9mLH9N59fH7h2woCbgR-wcBVLlGB5LBIdGqViLUTKTRqrjCWxYliEGeoItmw4NknRgZeDi82Ylwud-LHmwPcSuRzx0Mc7Fo27YA_0iBC2VI9H_tAiY2dWFmbHg1skcMj8iimsJwZ0dmEw-15W5zm9f-durhjD_evkmvVi6W4Du3WyZooNHABtk0U2yLrVGRV9ahtbP7tBvnWZd5PpjJY5xTf96fyMqmmFqWYlcKTTgmZtu2VaFhSANC-nmk7AuYanomiIkQcSrrSjek5TisN-5wtad8y9SU4uRBS3yKCAbWwSyoFT4OcqB28nSH3gqI2f88iLMmZEEjjEbc9dzpqeHrL-sBdBLNQcoEQ5SSsnh7xC4XS02JG7_qGcn0p7waXSRsP2Uwj540BHJgWkGz9MlTIijPzEIdsoWtmUt3Z6Re5ihA1BW-w75GFNgV05CsT3abqsKjn68OU_iI4_9YieWKK8BJBkqS21gGfCbl89yq0eJeiWrLe8iUBsT6WSf24h_LMF5_nLD7plZIqpfIUplw1NEgeccYfcbrDcnWwAJoWDHXBI3EN57-j7K8V0UjdFxxrwCMLtO__e1za5AmpDvhsdHd4lVxkOc_ZCl7EtMljMl-YeeJgLdb--ypR8vWjd8Rt_g5Eo
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Relationship+of+urinary+bisphenol+A+in+childhood+on+thyroid+hormone+function+in+adolescents%3A+a+cohort+study&rft.jtitle=PloS+one&rft.au=Choi%2C+Jung+Eun&rft.au=Choi%2C+Eun+Jeong&rft.au=Lee%2C+Seonhwa&rft.au=Park%2C+Bohyun&rft.date=2025-05-22&rft.issn=1932-6203&rft.eissn=1932-6203&rft.volume=20&rft.issue=5&rft.spage=e0322658&rft_id=info:doi/10.1371%2Fjournal.pone.0322658&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon