Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes - Novikova, Gloriia; Kapoor, Manav; TCW, Julia; Abud, Edsel M.; Efthymiou, Anastasia G.; Chen, Steven X.; Cheng, Haoxiang; Fullard, John F.; Bendl, Jaroslav; Liu, Yiyuan; Roussos, Panos; Björkegren, Johan LM; et al. (Nature communications, 2021)
Keywords: 631/114/2785; 631/208/191; 631/378/1689/1283; 631/378/371; Alleles; Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer's disease; Annotations; Datasets; Enhancers; Gene expression; Gene Expression Regulation; Gene mapping; Gene regulation; Genes; Genetic Predisposition to Disease - genetics; Genetics; Genome-wide association studies; Genome-Wide Association Study; Genomics; Health risks; Humanities and Social Sciences; Humans; Induced Pluripotent Stem Cells - metabolism; Loci; Macrophages; Microglia; Microglia - metabolism; Monocytes; multidisciplinary; Myeloid Cells; Neurodegenerative diseases; Nominations; Pathogenesis; Pluripotency; Regulatory sequences; Regulatory Sequences, Nucleic Acid - genetics; Risk; Science; Science (multidisciplinary); Stem cells; Transcriptome