Pneumococcal colonization dynamics among young children with and without respiratory symptoms during the first year of the SARS-CoV-2 pandemic

• Published in: PloS one Vol. 20; no. 6; p. e0327046
• Main Authors: Olarte, Liset, Lee, Brian, Banerjee, Dithi, Swanson, Douglas S., Harrison, Christopher J., Selvarangan, Rangaraj
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 26.06.2025; Public Library of Science (PLoS)
• Subjects: Antibiotics; Asymptomatic; Bacterial infections; Biology and life sciences; Child, Preschool; Children; Childrens health; Chronic illnesses; Colonization; COVID-19; COVID-19 - epidemiology; COVID-19 - virology; Cross-Sectional Studies; Data collection; Density; Deoxyribonucleic acid; DNA; Electronic health records; Epidemics; Female; Health aspects; Humans; Infant; Male; Medicine and health sciences; Missouri - epidemiology; Nose; Pandemics; Pediatric research; People and Places; Pharmaceuticals; Pneumococcal infections; Pneumococcal Infections - epidemiology; Pneumococcal Infections - microbiology; Population; Preschool children; Public health; Pulmonary manifestations of general diseases; Regression analysis; Research and Analysis Methods; Retrospective Studies; Risk factors; Sample size; SARS-CoV-2 - isolation & purification; Serotypes; Severe acute respiratory syndrome coronavirus 2; Shelter in place; Signs and symptoms; Social distancing; Statistics; Streptococcus infections; Streptococcus pneumoniae - isolation & purification; United States; Variables; Viral diseases; Winter; Missouri; United States; Kansas City Missouri; Kansas; United States > US

Non-pharmaceutical interventions to mitigate the spread of SARS-CoV-2 were implemented across the United States in 2020. These public health measures might influence pneumococcal colonization in younger children and their subsequent risk of invasive pneumococcal disease. Our objective was to evaluat...