Notch3 Is Necessary for Blood Vessel Integrity in the Central Nervous System - Henshall, Tanya L.; Keller, Annika; He, Liqun; Johansson, Bengt R.; Wallgard, Elisabet; Raschperger, Elisabeth; Mäe, Maarja Andaloussi; Jin, Shaobo; Betsholtz, Christer; Lendahl, Urban (Arteriosclerosis, thrombosis, and vascular biology, 2015)
Keywords: Actins - genetics; Actins - metabolism; aneurysm; Animals; Apoptosis; AUTOSOMAL-DOMINANT ARTERIOPATHY; Biomarkers - metabolism; Blood Vessels - metabolism; blood-brain barrier; Blood-Brain Barrier - metabolism; Blood-Brain Barrier - pathology; BRAIN-BARRIER; CADASIL; Capillary Permeability; DISEASE; Endothelial Cells - metabolism; EXPRESSION; Female; fibrin; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genotype; Hematologi; Hematology; INFARCTS; ISCHEMIC-STROKE; LEUKOENCEPHALOPATHY; Male; Mice, Inbred C57BL; Mice, Knockout; Microvessels - metabolism; Microvessels - pathology; Muscle, Smooth, Vascular - metabolism; Muscle, Smooth, Vascular - pathology; Myocytes, Smooth Muscle - metabolism; Myocytes, Smooth Muscle - pathology; Notch3; Pericytes - metabolism; Peripheral Vascular Disease; Phenotype; Receptor, Notch3; Receptors, Notch - deficiency; Receptors, Notch - genetics; Receptors, Notch - metabolism; Retinal Vessels - metabolism; Retinal Vessels - pathology; Signal Transduction; smooth muscle; SMOOTH-MUSCLE-CELLS; SUBCORTICAL; Transcription, Genetic; VASCULAR INTEGRITY; blood-brain barrier; smooth muscle; aneurysm; fibrin; Notch3