A comparison in the ability to detect diabetic retinopathy between fasting plasma glucose and HbA1c levels in a longitudinal study
Aims The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population. Materials and Metho...
Saved in:
| Published in | Endocrinology, Diabetes & Metabolism Vol. 4; no. 1; pp. e00196 - n/a |
|---|---|
| Main Authors | , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Wiley
01.01.2021
John Wiley & Sons, Inc John Wiley and Sons Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 2398-9238 2398-9238 |
| DOI | 10.1002/edm2.196 |
Cover
| Abstract | Aims
The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population.
Materials and Methods
The study subjects underwent health examinations twice (including eye test and questionnaire of lifestyle and health) in 2008‐2009 (baseline) and in 2012‐2013 (4‐year follow‐up). Both non‐DM and DM patients at baseline were included as the participants. Of these participants, who had not been diagnosed with retinopathy at the baseline survey (n = 2427; 2150 men and 277 women) had eye fundus photographs taken four years later (follow‐up survey). The odds ratios of incidence of retinopathy according to the eight groups of FPG and HbA1c were estimated using multiple logistic regression analysis adjusted for sex and age. Receiver operator characteristic analysis was used to evaluate each value associated with the presence or absence of retinopathy.
Results
The odds ratios (95% confidence intervals) of incidence of retinopathy by HbA1c level categories, in ascending order, were 1.0 (ref.), 5.66 (1.14‐28.26), 1.69 (0.24‐12.04), 3.03 (0.50‐18.28), 1.04 (0.09‐11.59), 4.73 (0.78‐28.69), 4.12 (0.74‐22.85) and 24.47 (5.61‐106.75). For both FPG and HbA1c levels, the odds ratio for the development of retinopathy increased linearly with the increases in the levels FPG and HbA1c, and no clear threshold was observed. The AUC values (SE) for FPG and HbA1c were almost the same, at 0.750 (0.046) and 0.732 (0.048).
Conclusions
It was clarified that the higher the level of FPG and HbA1c was, the higher the incidence of retinopathy after 4 years was. There was no clear threshold. The detection ability of the incidence of retinopathy was almost the same between FPG and HbA1c, suggesting it is possible to detect the risk of retinopathy by HbA1c only.
A comparison in the ability to detect diabetic retinopathy between fasting plasma glucose and HbA1c levels in a longitudinal study. |
|---|---|
| AbstractList | A comparison in the ability to detect diabetic retinopathy between fasting plasma glucose and HbA1c levels in a longitudinal study. The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population. The study subjects underwent health examinations twice (including eye test and questionnaire of lifestyle and health) in 2008-2009 (baseline) and in 2012-2013 (4-year follow-up). Both non-DM and DM patients at baseline were included as the participants. Of these participants, who had not been diagnosed with retinopathy at the baseline survey (n = 2427; 2150 men and 277 women) had eye fundus photographs taken four years later (follow-up survey). The odds ratios of incidence of retinopathy according to the eight groups of FPG and HbA1c were estimated using multiple logistic regression analysis adjusted for sex and age. Receiver operator characteristic analysis was used to evaluate each value associated with the presence or absence of retinopathy. The odds ratios (95% confidence intervals) of incidence of retinopathy by HbA1c level categories, in ascending order, were 1.0 (ref.), 5.66 (1.14-28.26), 1.69 (0.24-12.04), 3.03 (0.50-18.28), 1.04 (0.09-11.59), 4.73 (0.78-28.69), 4.12 (0.74-22.85) and 24.47 (5.61-106.75). For both FPG and HbA1c levels, the odds ratio for the development of retinopathy increased linearly with the increases in the levels FPG and HbA1c, and no clear threshold was observed. The AUC values (SE) for FPG and HbA1c were almost the same, at 0.750 (0.046) and 0.732 (0.048). It was clarified that the higher the level of FPG and HbA1c was, the higher the incidence of retinopathy after 4 years was. There was no clear threshold. The detection ability of the incidence of retinopathy was almost the same between FPG and HbA1c, suggesting it is possible to detect the risk of retinopathy by HbA1c only. Aims The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population. Materials and Methods The study subjects underwent health examinations twice (including eye test and questionnaire of lifestyle and health) in 2008‐2009 (baseline) and in 2012‐2013 (4‐year follow‐up). Both non‐DM and DM patients at baseline were included as the participants. Of these participants, who had not been diagnosed with retinopathy at the baseline survey (n = 2427; 2150 men and 277 women) had eye fundus photographs taken four years later (follow‐up survey). The odds ratios of incidence of retinopathy according to the eight groups of FPG and HbA1c were estimated using multiple logistic regression analysis adjusted for sex and age. Receiver operator characteristic analysis was used to evaluate each value associated with the presence or absence of retinopathy. Results The odds ratios (95% confidence intervals) of incidence of retinopathy by HbA1c level categories, in ascending order, were 1.0 (ref.), 5.66 (1.14‐28.26), 1.69 (0.24‐12.04), 3.03 (0.50‐18.28), 1.04 (0.09‐11.59), 4.73 (0.78‐28.69), 4.12 (0.74‐22.85) and 24.47 (5.61‐106.75). For both FPG and HbA1c levels, the odds ratio for the development of retinopathy increased linearly with the increases in the levels FPG and HbA1c, and no clear threshold was observed. The AUC values (SE) for FPG and HbA1c were almost the same, at 0.750 (0.046) and 0.732 (0.048). Conclusions It was clarified that the higher the level of FPG and HbA1c was, the higher the incidence of retinopathy after 4 years was. There was no clear threshold. The detection ability of the incidence of retinopathy was almost the same between FPG and HbA1c, suggesting it is possible to detect the risk of retinopathy by HbA1c only. A comparison in the ability to detect diabetic retinopathy between fasting plasma glucose and HbA1c levels in a longitudinal study. AimsThe relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population.Materials and MethodsThe study subjects underwent health examinations twice (including eye test and questionnaire of lifestyle and health) in 2008‐2009 (baseline) and in 2012‐2013 (4‐year follow‐up). Both non‐DM and DM patients at baseline were included as the participants. Of these participants, who had not been diagnosed with retinopathy at the baseline survey (n = 2427; 2150 men and 277 women) had eye fundus photographs taken four years later (follow‐up survey). The odds ratios of incidence of retinopathy according to the eight groups of FPG and HbA1c were estimated using multiple logistic regression analysis adjusted for sex and age. Receiver operator characteristic analysis was used to evaluate each value associated with the presence or absence of retinopathy.ResultsThe odds ratios (95% confidence intervals) of incidence of retinopathy by HbA1c level categories, in ascending order, were 1.0 (ref.), 5.66 (1.14‐28.26), 1.69 (0.24‐12.04), 3.03 (0.50‐18.28), 1.04 (0.09‐11.59), 4.73 (0.78‐28.69), 4.12 (0.74‐22.85) and 24.47 (5.61‐106.75). For both FPG and HbA1c levels, the odds ratio for the development of retinopathy increased linearly with the increases in the levels FPG and HbA1c, and no clear threshold was observed. The AUC values (SE) for FPG and HbA1c were almost the same, at 0.750 (0.046) and 0.732 (0.048).ConclusionsIt was clarified that the higher the level of FPG and HbA1c was, the higher the incidence of retinopathy after 4 years was. There was no clear threshold. The detection ability of the incidence of retinopathy was almost the same between FPG and HbA1c, suggesting it is possible to detect the risk of retinopathy by HbA1c only. The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population.AimsThe relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population.The study subjects underwent health examinations twice (including eye test and questionnaire of lifestyle and health) in 2008-2009 (baseline) and in 2012-2013 (4-year follow-up). Both non-DM and DM patients at baseline were included as the participants. Of these participants, who had not been diagnosed with retinopathy at the baseline survey (n = 2427; 2150 men and 277 women) had eye fundus photographs taken four years later (follow-up survey). The odds ratios of incidence of retinopathy according to the eight groups of FPG and HbA1c were estimated using multiple logistic regression analysis adjusted for sex and age. Receiver operator characteristic analysis was used to evaluate each value associated with the presence or absence of retinopathy.Materials and MethodsThe study subjects underwent health examinations twice (including eye test and questionnaire of lifestyle and health) in 2008-2009 (baseline) and in 2012-2013 (4-year follow-up). Both non-DM and DM patients at baseline were included as the participants. Of these participants, who had not been diagnosed with retinopathy at the baseline survey (n = 2427; 2150 men and 277 women) had eye fundus photographs taken four years later (follow-up survey). The odds ratios of incidence of retinopathy according to the eight groups of FPG and HbA1c were estimated using multiple logistic regression analysis adjusted for sex and age. Receiver operator characteristic analysis was used to evaluate each value associated with the presence or absence of retinopathy.The odds ratios (95% confidence intervals) of incidence of retinopathy by HbA1c level categories, in ascending order, were 1.0 (ref.), 5.66 (1.14-28.26), 1.69 (0.24-12.04), 3.03 (0.50-18.28), 1.04 (0.09-11.59), 4.73 (0.78-28.69), 4.12 (0.74-22.85) and 24.47 (5.61-106.75). For both FPG and HbA1c levels, the odds ratio for the development of retinopathy increased linearly with the increases in the levels FPG and HbA1c, and no clear threshold was observed. The AUC values (SE) for FPG and HbA1c were almost the same, at 0.750 (0.046) and 0.732 (0.048).ResultsThe odds ratios (95% confidence intervals) of incidence of retinopathy by HbA1c level categories, in ascending order, were 1.0 (ref.), 5.66 (1.14-28.26), 1.69 (0.24-12.04), 3.03 (0.50-18.28), 1.04 (0.09-11.59), 4.73 (0.78-28.69), 4.12 (0.74-22.85) and 24.47 (5.61-106.75). For both FPG and HbA1c levels, the odds ratio for the development of retinopathy increased linearly with the increases in the levels FPG and HbA1c, and no clear threshold was observed. The AUC values (SE) for FPG and HbA1c were almost the same, at 0.750 (0.046) and 0.732 (0.048).It was clarified that the higher the level of FPG and HbA1c was, the higher the incidence of retinopathy after 4 years was. There was no clear threshold. The detection ability of the incidence of retinopathy was almost the same between FPG and HbA1c, suggesting it is possible to detect the risk of retinopathy by HbA1c only.ConclusionsIt was clarified that the higher the level of FPG and HbA1c was, the higher the incidence of retinopathy after 4 years was. There was no clear threshold. The detection ability of the incidence of retinopathy was almost the same between FPG and HbA1c, suggesting it is possible to detect the risk of retinopathy by HbA1c only. Abstract Aims The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting plasma glucose (FPG) is more effective for detecting the diabetic retinopathy longitudinally in a Japanese population. Materials and Methods The study subjects underwent health examinations twice (including eye test and questionnaire of lifestyle and health) in 2008‐2009 (baseline) and in 2012‐2013 (4‐year follow‐up). Both non‐DM and DM patients at baseline were included as the participants. Of these participants, who had not been diagnosed with retinopathy at the baseline survey (n = 2427; 2150 men and 277 women) had eye fundus photographs taken four years later (follow‐up survey). The odds ratios of incidence of retinopathy according to the eight groups of FPG and HbA1c were estimated using multiple logistic regression analysis adjusted for sex and age. Receiver operator characteristic analysis was used to evaluate each value associated with the presence or absence of retinopathy. Results The odds ratios (95% confidence intervals) of incidence of retinopathy by HbA1c level categories, in ascending order, were 1.0 (ref.), 5.66 (1.14‐28.26), 1.69 (0.24‐12.04), 3.03 (0.50‐18.28), 1.04 (0.09‐11.59), 4.73 (0.78‐28.69), 4.12 (0.74‐22.85) and 24.47 (5.61‐106.75). For both FPG and HbA1c levels, the odds ratio for the development of retinopathy increased linearly with the increases in the levels FPG and HbA1c, and no clear threshold was observed. The AUC values (SE) for FPG and HbA1c were almost the same, at 0.750 (0.046) and 0.732 (0.048). Conclusions It was clarified that the higher the level of FPG and HbA1c was, the higher the incidence of retinopathy after 4 years was. There was no clear threshold. The detection ability of the incidence of retinopathy was almost the same between FPG and HbA1c, suggesting it is possible to detect the risk of retinopathy by HbA1c only. |
| Author | Shuichiro Yamamoto Tetsuji Yokoyama Naotatsu Katai Norio Takeda Yosuke Nakamura Mitsuhiko Noda Yumi Matsushita Natsuyo Yoshida‐Hata Tetsuya Mizoue Toru Nakagawa |
| AuthorAffiliation | 3 Takeda Eye Clinic Chiba Japan 5 Hikaru Eye Clinic Saitama Japan 1 Department of Clinical Research National Center for Global Health and Medicine Tokyo Japan 4 Department of ophthalmology Shimoda Medical Center Shizuoka Japan 8 Department of Diabetes, Metabolism and Endocrinology Ichikawa Hospital International University of Health and Welfare Chiba Japan 2 Department of Health Promotion National Institute of Public Health Saitama Japan 7 Hitachi, Ltd. Hitachi Health Care Center Ibaraki Japan 9 Department of Epidemiology and Prevention National Center for Global Health and Medicine Tokyo Japan 6 Department of ophthalmology Kimitsu Chuo Hospital Chiba Japan |
| AuthorAffiliation_xml | – name: 9 Department of Epidemiology and Prevention National Center for Global Health and Medicine Tokyo Japan – name: 4 Department of ophthalmology Shimoda Medical Center Shizuoka Japan – name: 5 Hikaru Eye Clinic Saitama Japan – name: 7 Hitachi, Ltd. Hitachi Health Care Center Ibaraki Japan – name: 6 Department of ophthalmology Kimitsu Chuo Hospital Chiba Japan – name: 2 Department of Health Promotion National Institute of Public Health Saitama Japan – name: 3 Takeda Eye Clinic Chiba Japan – name: 8 Department of Diabetes, Metabolism and Endocrinology Ichikawa Hospital International University of Health and Welfare Chiba Japan – name: 1 Department of Clinical Research National Center for Global Health and Medicine Tokyo Japan |
| Author_xml | – sequence: 1 givenname: Yumi orcidid: 0000-0003-0071-8293 surname: Matsushita fullname: Matsushita, Yumi email: ymatsushita@hosp.ncgm.go.jp organization: National Center for Global Health and Medicine – sequence: 2 givenname: Tetsuji surname: Yokoyama fullname: Yokoyama, Tetsuji organization: National Institute of Public Health – sequence: 3 givenname: Norio surname: Takeda fullname: Takeda, Norio organization: Takeda Eye Clinic – sequence: 4 givenname: Naotatsu surname: Katai fullname: Katai, Naotatsu organization: Shimoda Medical Center – sequence: 5 givenname: Natsuyo surname: Yoshida‐Hata fullname: Yoshida‐Hata, Natsuyo organization: Hikaru Eye Clinic – sequence: 6 givenname: Yosuke surname: Nakamura fullname: Nakamura, Yosuke organization: Kimitsu Chuo Hospital – sequence: 7 givenname: Shuichiro surname: Yamamoto fullname: Yamamoto, Shuichiro organization: Hitachi, Ltd. Hitachi Health Care Center – sequence: 8 givenname: Mitsuhiko surname: Noda fullname: Noda, Mitsuhiko organization: International University of Health and Welfare – sequence: 9 givenname: Tetsuya surname: Mizoue fullname: Mizoue, Tetsuya organization: National Center for Global Health and Medicine – sequence: 10 givenname: Toru surname: Nakagawa fullname: Nakagawa, Toru organization: Hitachi, Ltd. Hitachi Health Care Center |
| BackLink | https://cir.nii.ac.jp/crid/1870020693129567360$$DView record in CiNii https://www.ncbi.nlm.nih.gov/pubmed/33532623$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1ks9vFCEUgCemxtbaxL_AkOjBy678mhnmYrKp1Tap8aJnwsBjl4aBdWDa7NW_XKZba9voBcjj4-M9eC-rgxADVNVrgpcEY_oBzECXpGueVUeUdWLRUSYOHqwPq5OUXI85JQR3HL-oDhmrGW0oO6p-rZCOw1aNLsWAXEB5A0j1zru8QzkiAxl0RsapHrLTaCxjiFuVNztUIjcAAVmVSnCNtl6lQaG1n3RMxRIMOu9XRCMP1-DTbFfIx7B2eTIuKI9SWexeVc-t8glO7ubj6sfns--n54vLb18uTleXC91w1ixazYH0hlNja8NxS1vCDHCBO-hbKzABCqy2tK8FcENNoxRgQ4DUHKzVLTuuLvZeE9WV3I5uUONORuXkbSCOa6nGUqMHaS2lmPfQ1K3hdWOV0rinprOABRNMF9fHvWs79QMYDSGPyj-SPt4JbiPX8Vq2ghFKRBG8vxOM8ecEKcvBJQ3eqwBxSpJy0ZC6aes577dP0Ks4jeX5bilMO1G3vFBvHmZ0n8qfr_57ox5jSiPYe4RgOTeSnBtJlkYq6PIJql1W2cW5Fuf_dWCxP3DjPOz-K5Znn77SPf9uzwfninseiWgLipuuvE9XCmcNZr8Bqbnkjw |
| CitedBy_id | crossref_primary_10_2174_0118743641277168231201102545 crossref_primary_10_1002_jcla_24966 crossref_primary_10_3390_ijms24098227 |
| Cites_doi | 10.2337/dc09-0440 10.1016/j.diabres.2016.12.013 10.1371/journal.pone.0154411 10.1007/s00592-013-0452-3 10.2337/dc09-9033 10.1016/j.ajo.2009.02.031 10.1136/bmj.308.6940.1323 10.1016/j.diabres.2014.04.003 10.5812/ircmj.31254 10.2337/db12-0103 10.2337/diacare.20.5.785 10.2337/diacare.21.9.1414 10.1016/S0161-6420(03)00815-7 |
| ContentType | Journal Article |
| Copyright | 2020 The Authors. published by John Wiley & Sons Ltd. 2020 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd. 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: 2020 The Authors. published by John Wiley & Sons Ltd. – notice: 2020 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd. – notice: 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | RYH 24P AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH K9. M0S PHGZM PHGZT PIMPY PKEHL PQEST PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.1002/edm2.196 |
| DatabaseName | CiNii Complete Wiley Online Library Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One ProQuest Central Proquest Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni) ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest One Academic Eastern Edition ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Central China ProQuest Hospital Collection (Alumni) ProQuest Central ProQuest Health & Medical Complete Health Research Premium Collection ProQuest One Academic UKI Edition Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Central (New) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE Publicly Available Content Database MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: 24P name: Wiley Online Library Open Access url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html sourceTypes: Publisher – sequence: 3 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 4 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 5 dbid: 7X7 name: Health & Medical Collection (Proquest) url: https://search.proquest.com/healthcomplete sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| DocumentTitleAlternate | MATSUSHITA et al |
| EISSN | 2398-9238 |
| EndPage | n/a |
| ExternalDocumentID | oai_doaj_org_article_ff2204be657d456faac0b2d9fe08383c PMC7831218 33532623 10_1002_edm2_196 EDM2196 |
| Genre | article Research Support, Non-U.S. Gov't Journal Article Comparative Study |
| GrantInformation_xml | – fundername: Ministry of Health, Labor and Welfare of Japan – fundername: Ministry of Education, Culture, Sports, Science and Technology of Japan – fundername: Grants‐in‐Aid for Research from the National Center for Global Health and Medicine funderid: 20A‐3002 – fundername: Grants‐in‐Aid for Research from the National Center for Global Health and Medicine grantid: 20A‐3002 |
| GroupedDBID | 0R~ 1OC 24P 7X7 8FI 8FJ AAHHS ABUWG ACCFJ ACCMX ACGFS ACXQS ADBBV ADKYN ADZMN ADZOD AEEZP AEQDE AFKRA AIWBW AJBDE ALIPV ALMA_UNASSIGNED_HOLDINGS ALUQN AOIJS AVUZU BCNDV BENPR BPHCQ BVXVI CCPQU EBS EMOBN FYUFA GROUPED_DOAJ HMCUK HYE M~E O9- OK1 OVD OVEED PHGZM PHGZT PIMPY PQQKQ PROAC RPM RYH TEORI UKHRP ADPDF EJD IAO IHR INH ITC WIN AAYXX CITATION AAMMB AEFGJ AGXDD AIDQK AIDYY CGR CUY CVF ECM EIF NPM 3V. 7XB 8FK AZQEC DWQXO K9. PKEHL PQEST PQUKI PRINS PUEGO 7X8 5PM |
| ID | FETCH-LOGICAL-c6436-7c4e1bd42df5d4072713de4809eb7f801e2e35f2b58e4d2d6aae0d1e154effc73 |
| IEDL.DBID | BENPR |
| ISSN | 2398-9238 |
| IngestDate | Wed Aug 27 01:24:05 EDT 2025 Thu Aug 21 18:02:15 EDT 2025 Thu Sep 04 15:01:35 EDT 2025 Sun Sep 07 03:44:55 EDT 2025 Mon Jul 21 06:06:58 EDT 2025 Tue Jul 01 02:03:16 EDT 2025 Thu Apr 24 22:57:32 EDT 2025 Wed Jan 22 16:30:14 EST 2025 Fri Jun 27 00:49:24 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | longitudinal study fasting plasma glucose retinopathy HbA1c |
| Language | English |
| License | Attribution 2020 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c6436-7c4e1bd42df5d4072713de4809eb7f801e2e35f2b58e4d2d6aae0d1e154effc73 |
| Notes | This study was supported by grants from the Ministry of Health, Labor and Welfare of Japan and the Ministry of Education, Culture, Sports, Science and Technology of Japan, and Grants‐in‐Aid for Research from the National Center for Global Health and Medicine (20A‐3002). ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Article-2 ObjectType-Feature-1 content type line 23 Funding information |
| ORCID | 0000-0003-0413-4631 0000-0003-0071-8293 |
| OpenAccessLink | https://www.proquest.com/docview/2480298574?pq-origsite=%requestingapplication%&accountid=15518 |
| PMID | 33532623 |
| PQID | 2480298574 |
| PQPubID | 4368364 |
| PageCount | 6 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_ff2204be657d456faac0b2d9fe08383c pubmedcentral_primary_oai_pubmedcentral_nih_gov_7831218 proquest_miscellaneous_2486156757 proquest_journals_2480298574 pubmed_primary_33532623 crossref_primary_10_1002_edm2_196 crossref_citationtrail_10_1002_edm2_196 wiley_primary_10_1002_edm2_196_EDM2196 nii_cinii_1870020693129567360 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | January 2021 |
| PublicationDateYYYYMMDD | 2021-01-01 |
| PublicationDate_xml | – month: 01 year: 2021 text: January 2021 |
| PublicationDecade | 2020 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England – name: Oxford – name: Hoboken |
| PublicationTitle | Endocrinology, Diabetes & Metabolism |
| PublicationTitleAlternate | Endocrinol Diabetes Metab |
| PublicationYear | 2021 |
| Publisher | Wiley John Wiley & Sons, Inc John Wiley and Sons Inc |
| Publisher_xml | – name: Wiley – name: John Wiley & Sons, Inc – name: John Wiley and Sons Inc |
| References | 2012; 61 2009; 32 1997; 20 2013; 50 2019 2006 1991 2016; 18 2016; 28 1998; 21 2017; 124 2014; 104 2009; 148 2003; 11 1994; 21 Sackett DL (e_1_2_7_7_1) 1991 e_1_2_7_5_1 e_1_2_7_4_1 International Diabetes Federation (e_1_2_7_3_1) 2019 e_1_2_7_9_1 e_1_2_7_8_1 Haynes RB (e_1_2_7_6_1) 2006 e_1_2_7_17_1 e_1_2_7_16_1 e_1_2_7_2_1 e_1_2_7_15_1 e_1_2_7_14_1 e_1_2_7_13_1 e_1_2_7_11_1 e_1_2_7_10_1 Martínez‐Vizcaíno V (e_1_2_7_12_1) 2016; 28 |
| References_xml | – volume: 21 start-page: 1323 issue: 308 year: 1994 end-page: 1328 article-title: Comparison of tests for glycated haemoglobin and fasting and two hour plasma glucose concentrations as diagnostic methods for diabetes publication-title: BMJ – volume: 18 year: 2016 article-title: Optimal glycemic and hemoglobin A1c thresholds for diagnosing diabetes based on prevalence of retinopathy in an Iranian population publication-title: Iran Red Crescent Med J – volume: 148 start-page: 111 year: 2009 end-page: 118 article-title: Screening for diabetic retinopathy: 1 and 3 nonmydriatic 45‐degree digital fundus photographs vs 7 standard early treatment diabetic retinopathy study fields publication-title: Am J Ophthalmol – volume: 50 start-page: 837 year: 2013 end-page: 842 article-title: Optimal HbA1c cutoff for detecting diabetic retinopathy publication-title: Acta Diabetol – volume: 28 issue: 11 year: 2016 article-title: The accuracy of diagnostic methods for diabetic retinopathy: a systematic review and meta‐analysis publication-title: PLoS One – volume: 61 start-page: 3280 year: 2012 end-page: 3284 article-title: New diabetes diagnostic threshold of hemoglobin A1c and the 3‐year incidence of retinopathy publication-title: Diabetes – volume: 124 start-page: 20 year: 2017 end-page: 29 article-title: Diabetes diagnostic thresholds of the glycated hemoglobin A1c and fasting plasma glucose levels considering the 5‐year incidence of retinopathy publication-title: Diabetes Res Clin Pract – volume: 32 start-page: 2027 year: 2009 end-page: 2032 article-title: Association of A1C and fasting plasma glucose levels with diabetic retinopathy prevalence in the U.S. population: implications for diabetes diagnostic thresholds publication-title: Diabetes Care – volume: 11 start-page: 1675 year: 2003 end-page: 1676 article-title: A simplified diabetic retinopathy scale publication-title: Ophthalmology – year: 2006 – volume: 20 start-page: 785 year: 1997 end-page: 791 article-title: Comparison of fasting and 2‐hour glucose and HbA1c levels for diagnosing diabetes. diagnostic criteria and performance revisited publication-title: Diabetes Care – volume: 32 start-page: 1327 year: 2009 end-page: 1334 article-title: International Expert Committee. International Expert Committee Report on the Role of the A1C Assay in the diagnosis of diabetes publication-title: Diabetes Care – volume: 21 start-page: 1414 year: 1998 end-page: 1431 article-title: Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections publication-title: Diabetes Care – year: 1991 – year: 2019 – volume: 104 start-page: 435 year: 2014 end-page: 442 article-title: Glycaemic and haemoglobin A1c thresholds for detecting diabetic retinopathy: the Fifth Korea National Health and Nutrition Examination Survey (2011) publication-title: Diabetes Res Clin Pract – ident: e_1_2_7_11_1 doi: 10.2337/dc09-0440 – ident: e_1_2_7_15_1 doi: 10.1016/j.diabres.2016.12.013 – volume: 28 start-page: e0154411 issue: 11 year: 2016 ident: e_1_2_7_12_1 article-title: The accuracy of diagnostic methods for diabetic retinopathy: a systematic review and meta‐analysis publication-title: PLoS One doi: 10.1371/journal.pone.0154411 – ident: e_1_2_7_8_1 doi: 10.1007/s00592-013-0452-3 – ident: e_1_2_7_4_1 doi: 10.2337/dc09-9033 – ident: e_1_2_7_17_1 doi: 10.1016/j.ajo.2009.02.031 – ident: e_1_2_7_14_1 doi: 10.1136/bmj.308.6940.1323 – ident: e_1_2_7_10_1 doi: 10.1016/j.diabres.2014.04.003 – ident: e_1_2_7_9_1 doi: 10.5812/ircmj.31254 – ident: e_1_2_7_16_1 doi: 10.2337/db12-0103 – ident: e_1_2_7_13_1 doi: 10.2337/diacare.20.5.785 – volume-title: IDF Diabetes Atlas year: 2019 ident: e_1_2_7_3_1 – volume-title: Clinical Epidemology. How to Do Clinical Practice Research year: 2006 ident: e_1_2_7_6_1 – ident: e_1_2_7_2_1 doi: 10.2337/diacare.21.9.1414 – ident: e_1_2_7_5_1 doi: 10.1016/S0161-6420(03)00815-7 – volume-title: Clinical Epidemology: A Basic Science for Clinical Medicine year: 1991 ident: e_1_2_7_7_1 |
| SSID | ssib042110940 ssj0001999602 |
| Score | 2.1598432 |
| Snippet | Aims
The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and... The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and fasting... AimsThe relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c and... A comparison in the ability to detect diabetic retinopathy between fasting plasma glucose and HbA1c levels in a longitudinal study. Abstract Aims The relationship between HbA1c and diabetic retinopathy is expected to differ between different races. In this study, we verified which of HbA1c... |
| SourceID | doaj pubmedcentral proquest pubmed crossref wiley nii |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | e00196 |
| SubjectTerms | Age Asian People Biomarkers Biomarkers - blood Blood Glucose Blood pressure Committees Diabetes Diabetic Retinopathy Diabetic Retinopathy - blood Diabetic Retinopathy - diagnosis Diabetic Retinopathy - epidemiology Disease Diseases of the endocrine glands. Clinical endocrinology Fasting Fasting - blood fasting plasma glucose Female Follow-Up Studies Glucose Glycated Hemoglobin HbA1c Hemoglobin Humans Logistic Models Longitudinal Studies longitudinal study Male Medical personnel Original Original s Plasma RC648-665 retinopathy Risk ROC Curve |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQD4gLUJ6hLTISglOo48R2clyg1QppOVGpt8iPsYi0Taru7qFXfjkzTrraFUVcuOSw9iYTzzjzjT3-hrH3ymkVQds8gihzOqqZ17YJeXSidmA0_o1OIy--6_lF9e1SXe6U-qKcsJEeeBy40xilFJUDrUxAZx-t9cLJ0OC9a4yuPH19RSN2gqm0ukI4nlJ3nkwso6cQruSngrj5d_xPoulHr9J33X0I889EyV0AmzzQ-VP2eIKOfDaKfMgeQP-MPVxMm-PP2a8Z99uqgrzrOWI7PtJw3_L1wAPQhgEfV1s7z-n8Yj9QSeJbPqVr8WhXlAfNrxFUX1k-JbRz2wc-d7PC8yUlGa3o7pYvByp2tAlUWIsnntoX7OL87MeXeT6VWMg9QhGdG19B4UIlQ1SBuNIwZg1Q1aIBZyJ6L5BQqiidqqEKMmhrQYQCEHhBjN6UL9lBP_TwmnHUMIIvhIvSiyrWrhEiorZAed1EfEzGPt4NfOsn_nEqg7FsR-Zk2ZKKWlRRxt5te16PnBv39PlMutu2E0t2-gFtp51sp_2X7WTsBDWP0tC1wC8XYmfd4Btg0GhKLTJ2fGcT7TS1V63E0ZFNrUyFcm6bcVLSTovtYdikPogUMRYzGXs1mtBW0rJUCJllmTGzZ1x7r7Lf0nc_E_G3qVG2os7Yh2SGfx2c9uzrAj2RfvM_BumIPZKUx5OWnY7ZwfpmAycIxNbubZpzvwEvQzKV priority: 102 providerName: Directory of Open Access Journals – databaseName: Wiley Online Library Open Access dbid: 24P link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lb9QwELagSIgL4t2UFhkJwSnUceJHjgu0WiEt4kCl3iI_IdI2qbq7h1755Z1xsikrisQlh_Vk43hmMp_t8TeEvBNWihikyWNgZY5HNXNtap9Hy7QNSsJteBp58U3Oz6qv5-J8zKrEszADP8S04Iaekb7X6ODGro5vSUODv-AfwX7ukwd4shbLNvDq--36CiL5lHKIDHc54Bi95Z5l_Hh78040SqT9EGO6tr0Lb_6dNvknnE3x6PQJeTwCSTobNP-U3AvdM_JwMW6VPye_Z9RNNQZp21FAenQg5b6m6576gNsHdFh7bR3F04xdjwWKr-mYvEWjWWFWNL0EiH1h6JjeTk3n6dzOCkeXmHK0wn83dNlj6aONxzJbNLHWviBnpyc_Ps_zseBC7gCYyFy5KhTWV9xH4ZE5DWawPlSa1cGqCLEs8FCKyK3QofLcS2MC80UAGBZidKp8Sfa6vgv7hIK-AYoBeOSOVVHbmrEYQVw4WUd4TEY-bAe-cSMbORbFWDYDjzJvUEUNqCgjbyfJy4GB4w6ZT6i7qR05s9MP_dXPZnTBJkbOWWWDFMoDbITeOGa5r8FKNczTXUaOQPPQG7wW8B0DJC1reAOYQqpSsowcbm2iGR191XAYHV5roSro59QMLor7LqYL_SbJAG6EmZnKyKvBhKaelqUAAM3LjKgd49p5ld2Wrv2VaMCVhr4VOiPvkxn-c3Caky8LiEvy4H8FX5NHHDN30kLTIdlbX23CEUCvtX2TfOwGJW0qgg priority: 102 providerName: Wiley-Blackwell |
| Title | A comparison in the ability to detect diabetic retinopathy between fasting plasma glucose and HbA1c levels in a longitudinal study |
| URI | https://cir.nii.ac.jp/crid/1870020693129567360 https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fedm2.196 https://www.ncbi.nlm.nih.gov/pubmed/33532623 https://www.proquest.com/docview/2480298574 https://www.proquest.com/docview/2486156757 https://pubmed.ncbi.nlm.nih.gov/PMC7831218 https://doaj.org/article/ff2204be657d456faac0b2d9fe08383c |
| Volume | 4 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lj9MwELb2ISEuvB-B3cpICE5hEyexkwNCXeiqQmq1QqzUWxS_IFI3Kdv2sFd-OTOOk92KhUsOtZtMMmPP5_H4G0LeZpJn1vAqtCZKQjyqGeZVoUMro1waweFveBp5NufTi_TrIlvskXl_FgbTKvs50U3UulUYIz9haY5s4ZlIP61-hVg1CndX-xIalS-toD86irF9cghTcg52f3g6mZ9_u4m6IL7HlJ6Hnn30xOhL9iFGzv5bfsnR94O3aer6LuT5dwLlbWDrPNPZI_LAQ0o67mzgMdkzzRNyb-Y3zZ-S32OqhmqDtG4oYD7a0XNf001LtcGNBNpFYWtF8Vxj02Kp4mvq07iordaYH01XALYvK-oT3WnVaDqV41jRJSYfrfHuFV22WARpq7HgFnX8tc_Ixdnk--dp6EsvhAogCg-FSk0sdcq0zTRyqMFaVhtQQWGksODVDDNJZpnMcpNqpnlVmUjHBgCZsVaJ5Dk5aNrGvCQUNA-gDGAkU1Fqc1lEkbXQPVO8sPCYgLzvP3ypPC85lsdYlh2jMitRRSWoKCBvhp6rjovjjj6nqLuhHdmz3Q_t1Y_SD8bSWsaiVBqeCQ0AEqRRkWS6AHvNYcWuAnIMmgdp8BrDjAaYmhfwBrCYFAmPAnLU20Tph_y6vDFQkHNohsGKOzBVY9qt6wMIEtZoIiAvOhMaJE2SDKA0SwIidoxr51V2W5r6pyMEFznIFucBeefM8J8fp5x8mYGH4q_-L_9rcp9h5o4LNB2Rg83V1hwD9NrIEdln6TlcxUKM_NgauTDGH_KPMpU |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB6VVAIuvB-GFhaJx8nUXttr-1ChlKZKaRMh1Eq9Ge8LIqV2aRKhXPlh_DZm7E3aiMKtlxyya3vsmZ39dnfmG4DXiRSJNaL0rQkin1I1_azMtW9lkEmTCryMspEHQ9E_jj-dJCdr8HuRC0NhlQuf2DhqXSvaI9_icUZs4Ukafzj74VPVKDpdXZTQKF1pBb3dUIy5xI4DM_-JS7jJ9v4u6vsN53u9o49931UZ8BXOxsJPVWxCqWOubaKJLgyXbdrg03IjU4sO3HATJZbLJDOx5lqUpQl0aBB7GGtVGuF9b8B6TBmuHVjf6Q0_f7nY5aH1BIUQ3XVsp1tGn_L3IdUIuDQPNuUCcHarRqOrkO7fAZuXgXQzE-7dgzsOwrJua3P3Yc1UD-DmwB3SP4RfXaaW1Q3ZqGKIMVlLBz5n05ppQwcXrN31HSlGeZRVTaWR58yFjTFbTigem50huD8tmQusZ2WlWV92Q8XGFOw0obuXbFxT0aWZpgJfrOHLfQTH16KEx9Cp6so8BYaWhiAQYStXQWwzmQeBtdg9USK3-BgP3i0-fKEcDzqV4xgXLYMzL0hFBarIg1fLnmct98cVfXZId8t2Yutu_qjPvxVu8BfWch7E0ogk1QhYURoVSK5zHB9ZlEXKg03UPEpDvyF6UMTwIsc3wMVrGonAg42FTRTOxUyKiwGBci6b0TnQiU9ZmXrW9EHEimvC1IMnrQktJY2iBKE7jzxIV4xr5VVWW6rR94aAPM1QtjDz4G1jhv_8OEVvd4Azonj2f_lfwq3-0eCwONwfHjyH25yihppNrg3oTM9nZhNh31S-cGOLwdfrHs5_AKvFbZE |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB6VVKq48H4YWlgkHicTe_1Y-1ChlCRKKYkqRKXeXHsfECm1Q5MI5crP41cxY2_SRhRuveSQXdtjz-zMt7uz3wC8joo4MjrOXaO9wKWjmm6Sp8o1hZcUWsR4GZ1GHo7iwUn46TQ63YLfq7MwlFa58om1o1aVpDXyNg8TYguPRNg2Ni3iuNv_MP3hUgUp2mldldPIbZkFtV_TjdlDHkd6-ROnc7P9wy7q_g3n_d7XjwPXVhxwJUbm2BUy1H6hQq5MpIg6DKdwSuOTU10Ig85ccx1EhhdRokPFVZzn2lO-RhyijZEiwPvegm2BUTJswfZBb3T85XLFh-YWlE501zKftrU65-99qhdwJSbWpQMw0pXj8XWo9-_kzauguo6K_Xtwx8JZ1mns7z5s6fIB7Azthv1D-NVhcl3pkI1LhniTNdTgSzavmNK0icGaFeCxZHSmsqyoTPKS2RQyZvIZ5WazKQL985zZJHuWl4oNio4v2YQSn2Z095xNKirAtFBU7IvV3LmP4ORGlPAYWmVV6qfA0OoQECKE5dILTVKknmcMdo9knBp8jAPvVh8-k5YTnUpzTLKGzZlnpKIMVeTAq3XPacMDck2fA9Ldup2Yu-s_qotvmXUEmTGce2Gh40goBK8ojfQKrlIcK0mQBNKBPdQ8SkO_PnpTxPNxim-AE1kRxJ4DuyubyKy7mWWXgwPlXDejo6Ddn7zU1aLug-gV54fCgSeNCa0lDYIIYTwPHBAbxrXxKpst5fh7TUYuEpTNTxx4W5vhPz9O1usOMTrGz_4v_0vYwWGdfT4cHT2H25wSiOr1rl1ozS8Weg8R4Lx4YYcWg7ObHs1_AINlcb0 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+comparison+in+the+ability+to+detect+diabetic+retinopathy+between+fasting+plasma+glucose+and+HbA1c+levels+in+a+longitudinal+study&rft.jtitle=Endocrinology%2C+diabetes+%26+metabolism&rft.au=Matsushita%2C+Yumi&rft.au=Yokoyama%2C+Tetsuji&rft.au=Takeda%2C+Norio&rft.au=Katai%2C+Naotatsu&rft.date=2021-01-01&rft.pub=John+Wiley+%26+Sons%2C+Inc&rft.eissn=2398-9238&rft.volume=4&rft.issue=1&rft_id=info:doi/10.1002%2Fedm2.196&rft.externalDBID=HAS_PDF_LINK |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2398-9238&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2398-9238&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2398-9238&client=summon |