1535-P: Physiological Role of Stress-Activated Neurons in the Paraventricular Hypothalamus

• Published in: Diabetes (New York, N.Y.) Vol. 72; no. Supplement_1; p. 1
• Main Authors: ESPINOZA, DIEGO G., ALVARSSON, ALEXANDRA, JIMENEZ GONZALEZ, MARIA, HAMPTON, ROLLIE F., LI, ROSEMARY Y., DEVARAKONDA, KAVYA, CHOUDHURY, JESLYN, WAXMAN, TALIA S., STANLEY, SARAH
• Format: Journal Article
• Language: English
• Published: New York American Diabetes Association 20.06.2023
• Subjects: Anxiety; Autonomic nervous system; Behavior; Corticosterone; Energy metabolism; Food intake; Glucose tolerance; Homeostasis; Hormones; Hypophagia; Hypothalamic-pituitary-adrenal axis; Hypothalamus; Immunohistochemistry; Metabolic response; Metabolism; Neural networks; Neurons; Neuropeptides; Oxytocin; Paraventricular nucleus; Stress response; Tyrosine 3-monooxygenase; Vasopressin

Psychological stimuli that disrupt homeostasis - stressors - lead to acute and chronic metabolic disturbance but the underlying neural circuits are incompletely understood. The paraventricular nucleus of the hypothalamus (PVH) plays a significant role in behavioral, autonomic and hormonal responses...