The relationship between mean corpuscular hemoglobin concentration and mortality in hypertensive individuals: A population-based cohort study

Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC an...

Full description

Saved in:
Bibliographic Details
Published inPloS one Vol. 19; no. 5; p. e0301903
Main Authors Li, Dan, Zhang, Qing, Ruan, Zhishen, Zhang, Yue, Liu, Xiaohe, Zhang, Guihong, Zhao, Hengyi, Li, Jing, Wu, Bo
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 09.05.2024
Public Library of Science (PLoS)
Subjects
Adult
Age
Aged
Analysis
Anemia
Blood pressure
Body mass index
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - blood
Cardiovascular Diseases - mortality
China
Chronic obstructive pulmonary disease
Cohort Studies
Confidence intervals
Diabetes
Erythrocyte Indices
Female
Glycosylated hemoglobin
Health aspects
Heart attacks
Heart failure
Hematology
Hemoglobin
Hemoglobins - analysis
Hemoglobins - metabolism
Humans
Hyperlipidemia
Hypertension
Hypertension - blood
Hypertension - mortality
Kidney diseases
Male
Marital status
Matching
Medical prognosis
Medical research
Medicine and Health Sciences
Medicine, Experimental
Middle Aged
Mortality
Nutrition Surveys
Patient outcomes
Physiological aspects
Population studies
Prognosis
Proportional Hazards Models
Pulmonary embolisms
Risk factors
Smoking
Statistical analysis
Subgroups
Surveys
United Kingdom
Variables
Viscosity
China
United Kingdom
Online AccessGet full text
ISSN1932-6203
1932-6203
DOI10.1371/journal.pone.0301903

Cover

Abstract Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients. We used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999-2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup. Our research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC ≤33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11-1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12-1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching. In hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.
AbstractList Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients. We used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999-2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup. Our research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC ≤33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11-1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12-1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching. In hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.
Introduction Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients. Methods We used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999–2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup. Results Our research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC ≤33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11–1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12–1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching. Conclusion In hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.
Introduction Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients. Methods We used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999-2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup. Results Our research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC [less than or equal to]33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11-1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12-1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching. Conclusion In hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.
Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients. We used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999-2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup. Our research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC [less than or equal to]33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11-1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12-1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching. In hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.
Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients.INTRODUCTIONHematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients.We used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999-2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup.METHODSWe used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999-2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup.Our research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC ≤33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11-1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12-1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching.RESULTSOur research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC ≤33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11-1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12-1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching.In hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.CONCLUSIONIn hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.
IntroductionHematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean corpuscular hemoglobin concentration (MCHC) is associated with a poor prognosis in several CVDs. There is no evidence of a correlation between MCHC and hypertension. Therefore, our study aimed to analyze the association of MCHC with all-cause and cardiovascular mortality in hypertensive patients.MethodsWe used cohort data from U.S. adults who participated in the National Health and Nutrition Examination Survey from 1999–2014. COX regression was applied to analyze the relationship between MCHC and all-cause and cardiovascular mortality. In addition, three models were adjusted to reduce confounding factors. We reanalyzed the data after propensity score matching (PSM) to inspect the stability of the results. Stratified analysis was additionally adopted to investigate the results of each subgroup.ResultsOur research included 15,154 individuals. During a mean follow-up period of 129 months, 30.6% of the hypertensive population succumbed to mortality. Based on previous studies, we categorized patients with MCHC ≤33mg/dl as the hypochromia group and those with >33mg/dl as the non-hypochromia group. After PSM, the hypochromia group had higher all-cause mortality (adjusted hazard ratio [HR]:1.26, 95% confidence interval [95%CI]:1.11–1.43) and cardiovascular mortality (adjusted HR:1.42, 95%CI:1.12–1.80) than the non-hypochromia group. The results of the COX regression remain stable after matching. Stratified analyses before PSM revealed an interaction of anemia in the relationship between MCHC and mortality, whereas there was no significant interaction after matching.ConclusionIn hypertensive individuals, low MCHC was correlated with a poor prognosis. Further studies on MCHC are necessary to analyze the potential mechanisms of its poor prognosis in hypertensive populations.
Audience Academic
Author Zhao, Hengyi
Li, Dan
Zhang, Yue
Wu, Bo
Li, Jing
Ruan, Zhishen
Zhang, Guihong
Zhang, Qing
Liu, Xiaohe
AuthorAffiliation 4 The First Affiliated Hospital of Shandong First Medical University, Jinan, People’s Republic of China
Xi’an Jiaotong University, CHINA
1 The First Clinical College, Shandong Chinese Medical University, Jinan, People’s Republic of China
2 Department of Emergency, Dongying People’s Hospital, Donging, People’s Republic of China
3 Department of Cardiovascular Medicine, The First Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, People’s Republic of China
AuthorAffiliation_xml – name: 1 The First Clinical College, Shandong Chinese Medical University, Jinan, People’s Republic of China
– name: Xi’an Jiaotong University, CHINA
– name: 2 Department of Emergency, Dongying People’s Hospital, Donging, People’s Republic of China
– name: 3 Department of Cardiovascular Medicine, The First Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, People’s Republic of China
– name: 4 The First Affiliated Hospital of Shandong First Medical University, Jinan, People’s Republic of China
Author_xml – sequence: 1
  givenname: Dan
  orcidid: 0000-0002-1898-0620
  surname: Li
  fullname: Li, Dan
– sequence: 2
  givenname: Qing
  surname: Zhang
  fullname: Zhang, Qing
– sequence: 3
  givenname: Zhishen
  surname: Ruan
  fullname: Ruan, Zhishen
– sequence: 4
  givenname: Yue
  surname: Zhang
  fullname: Zhang, Yue
– sequence: 5
  givenname: Xiaohe
  surname: Liu
  fullname: Liu, Xiaohe
– sequence: 6
  givenname: Guihong
  surname: Zhang
  fullname: Zhang, Guihong
– sequence: 7
  givenname: Hengyi
  surname: Zhao
  fullname: Zhao, Hengyi
– sequence: 8
  givenname: Jing
  surname: Li
  fullname: Li, Jing
– sequence: 9
  givenname: Bo
  orcidid: 0009-0000-9628-8579
  surname: Wu
  fullname: Wu, Bo
BackLink https://www.ncbi.nlm.nih.gov/pubmed/38722884$$D View this record in MEDLINE/PubMed
BookMark eNqNk9tu1DAQhiNURA_wBggiISG42MWOc7C5QauKQ6VKlaBwazn2ZOPKsYPtLOxD8M54u9tqF_UC-cLO-Jt_4l8zp9mRdRay7DlGc0wa_O7GTd4KMx9TeI4IwgyRR9kJZqSY1QUiR3vn4-w0hBuEKkLr-kl2TGhTFJSWJ9mf6x5yD0ZE7Wzo9Zi3EH8B2HwAYXPp_DgFORnh8x4GtzSu1ZuwlWCjv83KhVX54HwURsd1nq779Qg-gg16Belb6ZVWkzDhfb7IRzdO22qzVgRQSatPuXmIk1o_zR53iYNnu_0s-_7p4_X5l9nl1eeL88XlTNZlEWe0ozUB3DEloVWKlHWpMIYGMVY3RS0JINKpjlQ1Rg0g2uKm6Iq2ZkVVpZMkZ9nLre5oXOA7JwMnKCG0KhFLxMWWUE7c8NHrQfg1d0Lz24DzSy581NIAZxVrKSoZK0tcNoq1spGEqrJASlBGSNL6sKs2tQOorXPmQPTwxuqeL92KY4woJhVKCm92Ct79nCBEPuggwRhhwU2bH68IaxJYJ_TVP-jDz9tRS5FeoG3nUmG5EeWLJnVNVdNmQ80foNJSMOjUA9DpFD9IeHuQkJgIv-NSTCHwi29f_5-9-nHIvt5jexAm9sGZ6bZpD8EX-1bfe3zX8Akot4D0LgQP3T2CEd_M1Z1dfDNXfDdX5C-pGBbV
Cites_doi 10.1038/s41581-019-0244-2
10.1038/s41581-021-00454-y
10.1016/j.ijchy.2020.100061
ContentType Journal Article
Copyright Copyright: © 2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
COPYRIGHT 2024 Public Library of Science
2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2024 Li et al 2024 Li et al
2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright_xml – notice: Copyright: © 2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
– notice: COPYRIGHT 2024 Public Library of Science
– notice: 2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2024 Li et al 2024 Li et al
– notice: 2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
IOV
ISR
3V.
7QG
7QL
7QO
7RV
7SN
7SS
7T5
7TG
7TM
7U9
7X2
7X7
7XB
88E
8AO
8C1
8FD
8FE
8FG
8FH
8FI
8FJ
8FK
ABJCF
ABUWG
AEUYN
AFKRA
ARAPS
ATCPS
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
C1K
CCPQU
D1I
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
KB.
KB0
KL.
L6V
LK8
M0K
M0S
M1P
M7N
M7P
M7S
NAPCQ
P5Z
P62
P64
PATMY
PDBOC
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQQKQ
PQUKI
PRINS
PTHSS
PYCSY
RC3
7X8
5PM
DOA
DOI 10.1371/journal.pone.0301903
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Gale In Context: Opposing Viewpoints
Gale In Context: Science
ProQuest Central (Corporate)
Animal Behavior Abstracts
Bacteriology Abstracts (Microbiology B)
Biotechnology Research Abstracts
Nursing & Allied Health Database
Ecology Abstracts
Entomology Abstracts (Full archive)
Immunology Abstracts
Meteorological & Geoastrophysical Abstracts
Nucleic Acids Abstracts
Virology and AIDS Abstracts
Agricultural Science Collection
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
Public Health Database
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Collection
ProQuest Hospital Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
Materials Science & Engineering Collection (subscription)
ProQuest Central (Alumni)
ProQuest One Sustainability
ProQuest Central UK/Ireland
Advanced Technologies & Aerospace Collection
Agricultural & Environmental Science Collection
ProQuest Central Essentials
Biological Science Collection
ProQuest Central - New (Subscription)
Technology Collection
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Materials Science Collection
ProQuest Central
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Materials Science Database
Nursing & Allied Health Database (Alumni Edition)
Meteorological & Geoastrophysical Abstracts - Academic
ProQuest Engineering Collection
Biological Sciences
Agriculture Science Database
ProQuest Health & Medical Collection
PML(ProQuest Medical Library)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Engineering Database (subscription)
Nursing & Allied Health Premium
Advanced Technologies & Aerospace Database
ProQuest Advanced Technologies & Aerospace Collection
Biotechnology and BioEngineering Abstracts
Environmental Science Database
Materials Science Collection
ProQuest Central Premium
ProQuest One Academic
Publicly Available Content Database (subscription)
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Applied & Life Sciences
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
Engineering Collection
Environmental Science Collection
Genetics Abstracts
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Agricultural Science Database
Publicly Available Content Database
ProQuest Central Student
ProQuest Advanced Technologies & Aerospace Collection
ProQuest Central Essentials
Nucleic Acids Abstracts
SciTech Premium Collection
ProQuest Central China
Environmental Sciences and Pollution Management
ProQuest One Applied & Life Sciences
ProQuest One Sustainability
Health Research Premium Collection
Meteorological & Geoastrophysical Abstracts
Natural Science Collection
Health & Medical Research Collection
Biological Science Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
Engineering Collection
Advanced Technologies & Aerospace Collection
Engineering Database
Virology and AIDS Abstracts
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
Agricultural Science Collection
ProQuest Hospital Collection
ProQuest Technology Collection
Health Research Premium Collection (Alumni)
Biological Science Database
Ecology Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Environmental Science Collection
Entomology Abstracts
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Environmental Science Database
ProQuest Nursing & Allied Health Source (Alumni)
Engineering Research Database
ProQuest One Academic
Meteorological & Geoastrophysical Abstracts - Academic
ProQuest One Academic (New)
Technology Collection
Technology Research Database
ProQuest One Academic Middle East (New)
Materials Science Collection
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central
ProQuest Health & Medical Research Collection
Genetics Abstracts
ProQuest Engineering Collection
Biotechnology Research Abstracts
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Agricultural & Environmental Science Collection
AIDS and Cancer Research Abstracts
Materials Science Database
ProQuest Materials Science Collection
ProQuest Public Health
ProQuest Nursing & Allied Health Source
ProQuest SciTech Collection
Advanced Technologies & Aerospace Database
ProQuest Medical Library
Animal Behavior Abstracts
Materials Science & Engineering Collection
Immunology Abstracts
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE




MEDLINE - Academic


Agricultural Science Database
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals - NZ
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: 8FG
  name: ProQuest Technology Collection
  url: https://search.proquest.com/technologycollection1
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Sciences (General)
DocumentTitleAlternate The relationship between mean corpuscular hemoglobin concentration and mortality in hypertensive individuals
EISSN 1932-6203
ExternalDocumentID 3069285409
oai_doaj_org_article_959b8049944147d9bc7c38d420da8933
PMC11081350
A793256879
38722884
10_1371_journal_pone_0301903
Genre Research Support, Non-U.S. Gov't
Journal Article
GeographicLocations China
United Kingdom
GeographicLocations_xml – name: China
– name: United Kingdom
GrantInformation_xml – fundername: ;
  grantid: 0686-2211CA080200Z
GroupedDBID ---
123
29O
2WC
53G
5VS
7RV
7X2
7X7
7XC
88E
8AO
8C1
8CJ
8FE
8FG
8FH
8FI
8FJ
A8Z
AAFWJ
AAUCC
AAWOE
AAYXX
ABDBF
ABIVO
ABJCF
ABUWG
ACGFO
ACIHN
ACIWK
ACPRK
ACUHS
ADBBV
AEAQA
AENEX
AEUYN
AFKRA
AFPKN
AFRAH
AHMBA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
APEBS
ARAPS
ATCPS
BAWUL
BBNVY
BCNDV
BENPR
BGLVJ
BHPHI
BKEYQ
BPHCQ
BVXVI
BWKFM
CCPQU
CITATION
CS3
D1I
D1J
D1K
DIK
DU5
E3Z
EAP
EAS
EBD
EMOBN
ESX
EX3
F5P
FPL
FYUFA
GROUPED_DOAJ
GX1
HCIFZ
HH5
HMCUK
HYE
IAO
IEA
IGS
IHR
IHW
INH
INR
IOV
IPY
ISE
ISR
ITC
K6-
KB.
KQ8
L6V
LK5
LK8
M0K
M1P
M48
M7P
M7R
M7S
M~E
NAPCQ
O5R
O5S
OK1
OVT
P2P
P62
PATMY
PDBOC
PHGZM
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
PTHSS
PV9
PYCSY
RNS
RPM
RZL
SV3
TR2
UKHRP
WOQ
WOW
~02
~KM
3V.
ADRAZ
BBORY
CGR
CUY
CVF
ECM
EIF
IPNFZ
NPM
RIG
PMFND
7QG
7QL
7QO
7SN
7SS
7T5
7TG
7TM
7U9
7XB
8FD
8FK
AZQEC
C1K
DWQXO
FR3
GNUQQ
H94
K9.
KL.
M7N
P64
PJZUB
PKEHL
PPXIY
PQEST
PQGLB
PQUKI
PRINS
RC3
7X8
5PM
PUEGO
ESTFP
ID FETCH-LOGICAL-c642t-8f863e1f9dcebdd3464d11e70996726c3e03fdf356107e08b172f2b6925572fc3
IEDL.DBID M48
ISSN 1932-6203
IngestDate Thu Nov 28 02:59:10 EST 2024
Wed Aug 27 01:25:29 EDT 2025
Thu Aug 21 18:35:05 EDT 2025
Fri Jul 11 05:20:36 EDT 2025
Fri Jul 25 10:31:52 EDT 2025
Tue Jun 17 22:11:36 EDT 2025
Tue Jun 10 21:06:05 EDT 2025
Fri Jun 27 05:33:11 EDT 2025
Fri Jun 27 06:04:52 EDT 2025
Thu May 22 21:24:30 EDT 2025
Wed Feb 19 02:04:19 EST 2025
Tue Jul 01 00:34:30 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 5
Language English
License Copyright: © 2024 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Creative Commons Attribution License
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c642t-8f863e1f9dcebdd3464d11e70996726c3e03fdf356107e08b172f2b6925572fc3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
Competing Interests: The authors have declared that no competing interests exist.
DL and QZ are contributed equally to this work as the co-first authors
These authors also contributed equally to this work
ORCID 0009-0000-9628-8579
0000-0002-1898-0620
OpenAccessLink https://www.proquest.com/docview/3069285409?pq-origsite=%requestingapplication%
PMID 38722884
PQID 3069285409
PQPubID 1436336
PageCount e0301903
ParticipantIDs plos_journals_3069285409
doaj_primary_oai_doaj_org_article_959b8049944147d9bc7c38d420da8933
pubmedcentral_primary_oai_pubmedcentral_nih_gov_11081350
proquest_miscellaneous_3053975036
proquest_journals_3069285409
gale_infotracmisc_A793256879
gale_infotracacademiconefile_A793256879
gale_incontextgauss_ISR_A793256879
gale_incontextgauss_IOV_A793256879
gale_healthsolutions_A793256879
pubmed_primary_38722884
crossref_primary_10_1371_journal_pone_0301903
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2024-05-09
PublicationDateYYYYMMDD 2024-05-09
PublicationDate_xml – month: 05
  year: 2024
  text: 2024-05-09
  day: 09
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: San Francisco
– name: San Francisco, CA USA
PublicationTitle PloS one
PublicationTitleAlternate PLoS One
PublicationYear 2024
Publisher Public Library of Science
Public Library of Science (PLoS)
Publisher_xml – name: Public Library of Science
– name: Public Library of Science (PLoS)
References Yl H (pone.0301903.ref013) 2016; 4
M Choy (pone.0301903.ref018); 25
Gs S (pone.0301903.ref008) 2013; 22
(pone.0301903.ref002) 2018; 392
J Z (pone.0301903.ref004) 2022; 46
G C (pone.0301903.ref031) 1999; 21
M F (pone.0301903.ref032) 2014; 56
Z R (pone.0301903.ref012) 2022; 28
E C (pone.0301903.ref028) 2015; 112
El B (pone.0301903.ref030) 2014; 146
K L (pone.0301903.ref006) 2016; 26
H Y (pone.0301903.ref010) 2018; 40
L Y (pone.0301903.ref019) 2022; 14
G W (pone.0301903.ref034) 2005; 352
C S (pone.0301903.ref011) 2013; 19
Wc L (pone.0301903.ref025) 2017; 12
Yj T (pone.0301903.ref021) 2020; 17
KT Mills (pone.0301903.ref003) 2020; 16
W K (pone.0301903.ref022) 2020; 14
S D (pone.0301903.ref020) 2016; 32
M H (pone.0301903.ref014) 2022; 22
J Ma (pone.0301903.ref001) 2022; 9
Ml E (pone.0301903.ref029) 2016; 216
Ae Å (pone.0301903.ref009) 2014; 36
J Rana (pone.0301903.ref017) 2020; 7
E Brennan (pone.0301903.ref007) 2021; 17
Jm D (pone.0301903.ref026) 2006; 188
M F (pone.0301903.ref027) 2000; 15
Sj G (pone.0301903.ref024) 2017; 9
E von E (pone.0301903.ref016) 2007; 370
O S (pone.0301903.ref005) 1988; 36
X Q (pone.0301903.ref023) 2014; 10
Y F (pone.0301903.ref033) 2022; 9
Cl J (pone.0301903.ref015) 2014; 162
References_xml – volume: 188
  issue: 2
  year: 2006
  ident: pone.0301903.ref026
  article-title: Hemoglobin and atherosclerosis in patients with manifest arterial disease. The SMART-study
  publication-title: Atherosclerosis
– volume: 25
  start-page: 2023
  ident: pone.0301903.ref018
  article-title: Mean corpuscular haemoglobin concentration and outcomes in heart failure with preserved ejection fraction
  publication-title: ESC Heart Fail. Published online January
– volume: 9
  year: 2022
  ident: pone.0301903.ref033
  article-title: The Role of Interleukin-6 Family Members in Cardiovascular Diseases
  publication-title: Frontiers in cardiovascular medicine
– volume: 112
  issue: 38
  year: 2015
  ident: pone.0301903.ref028
  article-title: Piezo1 regulates mechanotransductive release of ATP from human RBCs
  publication-title: Proceedings of the National Academy of Sciences of the United States of America
– volume: 392
  issue: 10159
  year: 2018
  ident: pone.0301903.ref002
  article-title: Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017
  publication-title: Lancet (London, England)
– volume: 19
  issue: 4
  year: 2013
  ident: pone.0301903.ref011
  article-title: Prognostic implications of relative hypochromia in ambulatory patients with chronic systolic heart failure
  publication-title: Congestive heart failure (Greenwich, Conn)
– volume: 16
  start-page: 223
  issue: 4
  year: 2020
  ident: pone.0301903.ref003
  article-title: The global epidemiology of hypertension
  publication-title: Nature reviews Nephrology
  doi: 10.1038/s41581-019-0244-2
– volume: 36
  issue: Suppl 3
  year: 1988
  ident: pone.0301903.ref005
  article-title: Experiences from hypertension trials. Impact of other risk factors
  publication-title: Drugs
– volume: 17
  start-page: 725
  issue: 11
  year: 2021
  ident: pone.0301903.ref007
  article-title: Pro-resolving lipid mediators: regulators of inflammation, metabolism and kidney function
  publication-title: Nature Reviews Nephrology
  doi: 10.1038/s41581-021-00454-y
– volume: 9
  year: 2022
  ident: pone.0301903.ref001
  article-title: Advances in pathogenesis and treatment of essential hypertension
  publication-title: Frontiers in Cardiovascular Medicine
– volume: 32
  issue: 2
  year: 2016
  ident: pone.0301903.ref020
  article-title: A Review of Propensity-Score Methods and Their Use in Cardiovascular Research
  publication-title: The Canadian journal of cardiology
– volume: 26
  issue: 12
  year: 2016
  ident: pone.0301903.ref006
  article-title: Body Mass Index and the Risk of Cardiovascular and All-Cause Mortality Among Patients With Hypertension: A Population-Based Prospective Cohort Study Among Adults in Beijing, China
  publication-title: Journal of epidemiology
– volume: 162
  year: 2014
  ident: pone.0301903.ref015
  article-title: National health and nutrition examination survey: sample design, 2011–2014
  publication-title: Vital and health statistics Series 2, Data evaluation and methods research
– volume: 12
  issue: 7
  year: 2017
  ident: pone.0301903.ref025
  article-title: Anemia: A significant cardiovascular mortality risk after ST-segment elevation myocardial infarction complicated by the comorbidities of hypertension and kidney disease
  publication-title: PloS one
– volume: 22
  issue: 1
  year: 2022
  ident: pone.0301903.ref014
  article-title: Comparison of the red blood cell indices based on accuracy, sensitivity, and specificity to predict one-year mortality in heart failure patients
  publication-title: BMC cardiovascular disorders
– volume: 15
  issue: Suppl 3
  year: 2000
  ident: pone.0301903.ref027
  article-title: Pathophysiology of anaemia: focus on the heart and blood vessels
  publication-title: Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association—European Renal Association
– volume: 7
  year: 2020
  ident: pone.0301903.ref017
  article-title: Prevalence of hypertension and controlled hypertension among United States adults: Evidence from NHANES 2017–18 survey
  publication-title: International Journal of Cardiology Hypertension
  doi: 10.1016/j.ijchy.2020.100061
– volume: 10
  issue: 14
  year: 2014
  ident: pone.0301903.ref023
  article-title: Lower mean corpuscular hemoglobin concentration is associated with unfavorable prognosis of resected lung cancer
  publication-title: Future oncology (London, England)
– volume: 9
  issue: 12
  year: 2017
  ident: pone.0301903.ref024
  article-title: Prevalence, Comorbidity and Investigation of Anemia in the Primary Care Office
  publication-title: Journal of clinical medicine research
– volume: 4
  issue: 10
  year: 2016
  ident: pone.0301903.ref013
  article-title: Lower mean corpuscular hemoglobin concentration is associated with poorer outcomes in intensive care unit admitted patients with acute myocardial infarction
  publication-title: Annals of translational medicine
– volume: 370
  issue: 9596
  year: 2007
  ident: pone.0301903.ref016
  article-title: The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies
  publication-title: Lancet (London, England)
– volume: 28
  year: 2022
  ident: pone.0301903.ref012
  article-title: The Association Between Mean Corpuscular Hemoglobin Concentration and Prognosis in Patients with Acute Pulmonary Embolism: A Retrospective Cohort Study
  publication-title: Clinical and applied thrombosis/hemostasis: official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
– volume: 56
  issue: 4
  year: 2014
  ident: pone.0301903.ref032
  article-title: Association of red blood cell distribution width, inflammation markers and morphological as well as rheological erythrocyte parameters with target organ damage in hypertension
  publication-title: Clinical hemorheology and microcirculation
– volume: 22
  issue: 2
  year: 2013
  ident: pone.0301903.ref008
  article-title: Value of red cell distribution width (RDW) and RBC indices in the detection of iron deficiency anemia
  publication-title: Mymensingh medical journal: MMJ
– volume: 40
  issue: 7
  year: 2018
  ident: pone.0301903.ref010
  article-title: The relationship between anemia and pulse pressure and hypertension: The Korea National Health and Nutrition Examination Survey 2010–2012
  publication-title: Clinical and experimental hypertension (New York, NY: 1993)
– volume: 46
  issue: 2
  year: 2022
  ident: pone.0301903.ref004
  article-title: Time-varying association between body mass index and all-cause mortality in patients with hypertension
  publication-title: International journal of obesity (2005)
– volume: 14
  issue: 3
  year: 2022
  ident: pone.0301903.ref019
  article-title: Dietary Copper Intake and Risk of Stroke in Adults: A Case-Control Study Based on National Health and Nutrition Examination Survey 2013–2018
  publication-title: Nutrients
– volume: 14
  issue: 4
  year: 2020
  ident: pone.0301903.ref022
  article-title: Mean corpuscular hemoglobin concentration correlates with prognosis of resected hepatocellular carcinoma
  publication-title: Biomarkers in medicine
– volume: 146
  issue: 6
  year: 2014
  ident: pone.0301903.ref030
  article-title: Elevation of plasma cell-free hemoglobin in pulmonary arterial hypertension
  publication-title: Chest
– volume: 21
  issue: 3–4
  year: 1999
  ident: pone.0301903.ref031
  article-title: Red blood cell (RBC) deformability, RBC aggregability and tissue oxygenation in hypertension
  publication-title: Clinical hemorheology and microcirculation
– volume: 352
  issue: 10
  year: 2005
  ident: pone.0301903.ref034
  article-title: Anemia of chronic disease
  publication-title: The New England journal of medicine
– volume: 216
  issue: 3
  year: 2016
  ident: pone.0301903.ref029
  article-title: Role of erythrocyte-released ATP in the regulation of microvascular oxygen supply in skeletal muscle
  publication-title: Acta physiologica (Oxford, England)
– volume: 36
  issue: 1
  year: 2014
  ident: pone.0301903.ref009
  article-title: Empty iron stores in children and young adults—the diagnostic accuracy of MCV, MCH, and MCHC
  publication-title: International journal of laboratory hematology
– volume: 17
  issue: 2
  year: 2020
  ident: pone.0301903.ref021
  article-title: Risk Factors Associated with Outcomes of Recombinant Tissue Plasminogen Activator Therapy in Patients with Acute Ischemic Stroke
  publication-title: International journal of environmental research and public health
SSID ssj0053866
Score 2.4471114
Snippet Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that mean...
Introduction Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that...
IntroductionHematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that...
Introduction Hematology is an essential field for investigating the prognostic outcomes of cardiovascular diseases (CVDs). Recent research has suggested that...
SourceID plos
doaj
pubmedcentral
proquest
gale
pubmed
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage e0301903
SubjectTerms Adult
Age
Aged
Analysis
Anemia
Blood pressure
Body mass index
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - blood
Cardiovascular Diseases - mortality
China
Chronic obstructive pulmonary disease
Cohort Studies
Confidence intervals
Diabetes
Erythrocyte Indices
Female
Glycosylated hemoglobin
Health aspects
Heart attacks
Heart failure
Hematology
Hemoglobin
Hemoglobins - analysis
Hemoglobins - metabolism
Humans
Hyperlipidemia
Hypertension
Hypertension - blood
Hypertension - mortality
Kidney diseases
Male
Marital status
Matching
Medical prognosis
Medical research
Medicine and Health Sciences
Medicine, Experimental
Middle Aged
Mortality
Nutrition Surveys
Patient outcomes
Physiological aspects
Population studies
Prognosis
Proportional Hazards Models
Pulmonary embolisms
Risk factors
Smoking
Statistical analysis
Subgroups
Surveys
United Kingdom
Variables
Viscosity
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9NAEF6hnLggyquGAgtCAg5ube_au-YWEFVBAiSgqLfVvtxEIrYVJz-D_8yMvbZqVAkO3CLPOInnsfNNMg9CXhgHQaAyPtZclDFEaBEbborYcsckz3Ofefy949Pn4uycf7zIL66s-sKasGE88CC4kzIvjURcDnGbC1caKyyTjmeJ07gqHk9fiHljMjWcweDFRREa5ZhIT4Jejtum9seYBJTjkqwQiPp5_dOpvGh_Nt11kPPPyskroej0NrkVMCRdDt_9gNzw9R1yELy0o6_CKOnXd8kvsAK6HevdVuuWhrosuvG6ppB5tvuhEpWu_KbB6SBrvFwPn4x3UV07uulBOgB2CuQVpK7bUPhO11NDV_eGLmk77QOLMT46igt4tzvaT7G9R85P339_dxaHBQyxhbRkF8tKFsynVQnPa5xjvOAuTb0AVFmIrLDMJ6xyFUMMJnwiDaChKjNFCXkKvLLsPlnUIPJDQq3WPnHcCJ5DMu4zbTOP4E9qWejcphGJR22odpizofo_2wTkJ4NYFWpPBe1F5C2qbOLFKdn9BbAdFWxH_c12IvIUFa6GltPJ19USDi2AglKUEXnec-CkjBpLcS71vuvUhy8__oHp29cZ08vAVDWgQKtD-wM8E07gmnEezTjB3-2MfIjmOUqlU5D0ldgHm-Cdo8leT342kfFNsbyu9s0eeXLApTmgmYg8GCx8kiyTIsuk5BGRM9ufiX5OqderflA5tpikLE8e_g9lPSI3MwCUfbFpeUQWu-3ePwZAuDNPet__DSAoYAQ
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Public Health Database
  dbid: 8C1
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1Lb9QwELZguXBBlFcXChiEBBzSJrEdO1zQUlEVJEACinqL_Ep3JTYJm92fwX9mJnECQRXiFsWTl8cz840zD0KeGQdGoDQ-0lzmEVhoGRlusshyxxQXwqce9zs-fMxOz_j7c3EeNtzaEFY56MROUbva4h75EUDbHLP94vx18yPCrlH4dzW00LhKriWgg7F2vjoeQzxAlrMspMsxmRwF7hw2deUP0RXIh1ZZwRx1VftH3TxrvtftZcDz7_jJPwzSyU1yIyBJuuhZv0eu-OoW2Quy2tIXoaD0y9vkJ6wFuhmi3parhoboLLr2uqLgfza7Ph6VLv26xhohKzxd9U_Gq6iuHF13UB1gO4XhJTiwmxD-TldjWlf7ii5oM3YFi9BKOopteDdb2tWyvUPOTt5-PT6NQhuGyIJzso1UqTLmkzKH7zXOMZ5xlyReArbMZJpZ5mNWupIhEpM-VgYwUZkaYJcQcGTZXTKrYMr3CbVa-9hxI7kAl9yn2qYeIaDSKtPCJnMSDdwomr7aRtH9cpPgpfTTWiD3isC9OXmDLBtpsVZ2d6LeXBRB9Ipc5EahZwfIj0uXGystU46nsdOA1uAmj5HhRZ94Okp8sQDVBYBQyXxOnnYUWC-jwoCcC71r2-Ldp2__QfTl84ToeSAqa2Cg1SEJAr4J63BNKA8mlCD1djK8j8tzmJW2-C0fcOWwZC8ffjIO400xyK7y9Q5pBKBTAZhmTu71K3ycWaZkmirF50RN1v5k6qcj1WrZlSvHRJOEifj-v9_rAbmeAmDsgknzAzLbbnb-IQC-rXnUSfUvm4JYiQ
  priority: 102
  providerName: ProQuest
Title The relationship between mean corpuscular hemoglobin concentration and mortality in hypertensive individuals: A population-based cohort study
URI https://www.ncbi.nlm.nih.gov/pubmed/38722884
https://www.proquest.com/docview/3069285409
https://www.proquest.com/docview/3053975036
https://pubmed.ncbi.nlm.nih.gov/PMC11081350
https://doaj.org/article/959b8049944147d9bc7c38d420da8933
http://dx.doi.org/10.1371/journal.pone.0301903
Volume 19
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3db9MwELdG98ILYnwtMIpBSMBDqnw4sYOEUDetDKQNNCjqW5TEzlppTULSSvBH8D9z5zgRQUXaS1TFZ1e-O9u_i--DkJephEMgT5WdMB7ZcEJzO2VpaGdM-oIFgfIUfu84vwjP5uzTIljska5mq2Fgs9O0w3pS8_p68vPHr_ew4N_pqg3c7TpNqrJQE4T4Eab_3IeziWMxh3PW3yvA6ta3l4ha7NBzfBNM979RBoeVzunf79yj6rpsdsHSf70r_zquZnfJHYMz6bRVjAOyp4p75MCs5Ia-Numm39wnv0FTaN35xC1XFTW-W3StkoKCdVptW29VulTrEjOIrPB10f4z9qJJIela8xBAPYXmJZi3tXGOp6s-6Kt5S6e06muG2XiGSopFeusN1ZluH5D57PTbyZltijTYGZguG1vkIvSVm0cw31RKn4VMuq7igDxD7oWZrxw_l7mPOI0rR6SAmHIvDSOwZeBX5j8kowJYfkholiTKkSzlLACDXXlJ5ikEiCIRYRJkrkXsThpx1ebiiPWFHAcbpmVrjNKLjfQscowi62kxk7Z-UdZXsVmYcRREqUC7D3Ah4zJKM575QjLPkQlgORjkGQo8bsNS-_0gnsLGBnBR8MgiLzQFZtMo0F3nKtk2Tfzx8_cbEH29HBC9MkR5CQLMEhMiAXPCLF0DyqMBJewJ2aD5ENWz40oTg2EYYaysgz07ld3d_LxvxkHRBa9Q5RZpAsCuASAeizxqNbznrC-45wnBLCIGuj9g_bClWC11MnMMQ3H9wHl847k_Ibc9QJba6zQ6IqNNvVVPARlu0jG5xRccnuLExefsw5jsH59efLkc628tY70Z_AFF-mm5
linkProvider Scholars Portal
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db5RAEN_U80FfjPWrp9WuRqM-0AK7sIuJMWe1ubMfJtqaviHsLr1LPMDjLsY_wn_Fv9EZWFBMY3zpG2GHBXZmZ34D80HI41SDEchS4yRcRA5YaOGkPA0dxTWTPAiMb_B7x-FROD7h706D0zXys82FwbDKVifWiloXCr-R7wC0jTDbz41elV8d7BqFf1fbFhqNWOyb79_AZateTt4Af5_4_t7b492xY7sKOAqw9tKRmQyZ8bJIK5NqzXjItecZAVApFH6omHFZpjOGwEIYV6Zg4jM_hbsHARwpBvNeIpc5YwJr9cvdLqQEdEcY2vQ8JrwdKw3bZZGbbXQ9orY1lzV_dZeAzhYMyi9FdR7Q_Tte8w8DuHedXLPIlY4aUVsnaya_QdatbqjoM1vA-vlN8gNkjy7aKLvprKQ2GozOTZJT8HfLVRP_SqdmXmBNkhmezps741U0yTWd164BuAkUhqfgMC9suD2ddWlk1Qs6omXXhcxBq6wptv1dLGldO_cWObkQBt0mgxyWfINQlSTG1TwVPBDcN36ifIOQUyYyTALlDYnTciMum-oecf2LT4BX1CxrjNyLLfeG5DWyrKPF2tz1iWJxFtutHkdBlEr0JAFpcqGjVAnFpOa-qxNAhzDJFjI8bhJdOw0Tj0BVAgCVIhqSRzUF1ufIMQDoLFlVVTx5_-k_iD5-6BE9tURZAQxUiU26gHfCul89ys0eJWgZ1RveQPFsV6WKf-9HuLIV2fOHH3bDOCkG9eWmWCFNAGg4AAw1JHcaCe9Wlknh-1LyIZE92e8tfX8kn03r8uiY2OKxwL377-faIlfGx4cH8cHkaP8eueoDWK0DWaNNMlguVuY-gM1l-qDe4ZR8vmiV8gstNpSj
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1fb5RAEN_UMzG-GOu_nla7Go36QA-WhV1MjDmtTc9qNWrNvSHsLr1LPMDjLsYP4Rfy0zkDC4ppjC99I-ywwM7szG9g_hByP9VgBLLUOAkXkQMWWjgpT0NHce1LHgSGGfze8eYoPDjmr6bBdIP8bHNhMKyy1Ym1otaFwm_kI4C2EWb7udEos2ER7_b2n5VfHewghX9a23YajYgcmu_fwH2rnk72gNcPGNt_-fHFgWM7DDgKcPfKkZkMfeNlkVYm1drnIdeeZwTAplCwUPnG9TOd-QgyhHFlCuY-Yyk8SRDAkfJh3nPkvPDBbMJeEtPO2QM9EoY2Vc8X3shKxm5Z5GYX3ZCobdNlTWHdMaCzC4PyS1GdBnr_jt38wxjuXyaXLIql40bsNsmGya-QTasnKvrIFrN-fJX8ADmkyzbibjYvqY0MowuT5BR833LdxMLSmVkUWJ9kjqfz5s54FU1yTRe1mwAuA4XhGTjPSxt6T-ddSln1hI5p2XUkc9BCa4otgJcrWtfRvUaOz4RB18kghyXfIlQliXE1TwUPBGeGJYoZhJ8ykWESKG9InJYbcdlU-ojr330CPKRmWWPkXmy5NyTPkWUdLdbprk8Uy5PYbvs4CqJUolcJqJMLHaVKKF9qzlydAFKESXaQ4XGT9Nppm3gMahPAqBTRkNyrKbBWR45Sf5KsqyqevP30H0Qf3veIHlqirAAGqsQmYMA7YQ2wHuV2jxI0juoNb6F4tqtSxb_3JlzZiuzpw3e7YZwUA_xyU6yRJgBkHACeGpIbjYR3K-tLwZiUfEhkT_Z7S98fyeezulQ6Jrl4fuDe_Pdz7ZALoEzi15Ojw1vkIgPcWse0RttksFquzW3Anav0Tr3BKfl81hrlF2LvmQU
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+relationship+between+mean+corpuscular+hemoglobin+concentration+and+mortality+in+hypertensive+individuals%3A+A+population-based+cohort+study&rft.jtitle=PloS+one&rft.au=Li%2C+Dan&rft.au=Zhang%2C+Qing&rft.au=Ruan%2C+Zhishen&rft.au=Zhang%2C+Yue&rft.date=2024-05-09&rft.pub=Public+Library+of+Science&rft.issn=1932-6203&rft.eissn=1932-6203&rft.volume=19&rft.issue=5&rft.spage=e0301903&rft_id=info:doi/10.1371%2Fjournal.pone.0301903&rft.externalDocID=A793256879
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon