Evaluation of tarsal injuries in C57BL/6J male mice

• Published in: PloS one Vol. 18; no. 6; p. e0287204
• Main Authors: Kick, Brenda L., Anderson, Laura, Doty, Rosalinda, Wooley, Christine, Dyer, Meaghan, Green, Torrian, Knickerbocker, Veronica, Brown, Zoe, Loeber, Samantha, Wotton, Janine, Lyons, Bonnie, Waterman, Linda, Bichler, Zoë
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 26.06.2023; Public Library of Science (PLoS)
• Subjects: Abnormalities; Accreditation; Age; Animal experimentation; Animals; Ankylosis; Biology and Life Sciences; Body weight; Calcaneus; Care and treatment; Connective tissue diseases; Connective tissues; Diagnosis; Entrapment neuropathies; Evaluation; Females; Frailty; Histopathology; Inbreeding; Injuries; Joint diseases; Laboratory animals; Limbs; Male; Males; Medicine and Health Sciences; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Pain; Pain perception; Pilot projects; Research programs; Sensation; Social Sciences; Software; Tomography; Wheel running; United States

Tarsal joint abnormalities have been observed in aged male mice on a C57BL background. This joint disease consists of calcaneal displacement, inflammation, and proliferation of cartilage and connective tissue, that can progress to ankylosis of the joint. While tarsal pathology has been described pre...