1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses

• Published in: Nature biotechnology Vol. 37; no. 2; pp. 179 - 185
• Main Authors: Zou, Yuanqiang, Xue, Wenbin, Luo, Guangwen, Deng, Ziqing, Qin, Panpan, Guo, Ruijin, Sun, Haipeng, Xia, Yan, Liang, Suisha, Dai, Ying, Wan, Daiwei, Jiang, Rongrong, Su, Lili, Feng, Qiang, Jie, Zhuye, Guo, Tongkun, Xia, Zhongkui, Liu, Chuan, Yu, Jinghong, Lin, Yuxiang, Tang, Shanmei, Huo, Guicheng, Xu, Xun, Hou, Yong, Liu, Xin, Wang, Jian, Yang, Huanming, Kristiansen, Karsten, Li, Junhua, Jia, Huijue, Xiao, Liang
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.02.2019; Nature Publishing Group
• Subjects: 631/208/325/2482; 631/326/2565/2134; 631/326/41/2142; 631/326/41/2530; Agriculture; Analysis; Bacteria; Bacteria - classification; Bacterial genetics; Biodiversity; Bioinformatics; Biomedical and Life Sciences; Biomedical Engineering/Biotechnology; Biomedicine; Biotechnology; Cluster Analysis; Computational Biology - methods; Conserved Sequence; Feces; Gastrointestinal Microbiome; Gene mapping; Gene sequencing; Genetic aspects; Genome, Bacterial; Genomes; Genomics; Humans; Intestinal microflora; Life Sciences; Mapping; Metagenome; Metagenomics; Microbiomes; Microbiota; Microbiota (Symbiotic organisms); Phylogeny; Polymorphism, Single Nucleotide; Resource; RNA, Ribosomal, 16S - genetics; Sequence Analysis, DNA; Species diversity; China

Reference genomes are essential for metagenomic analyses and functional characterization of the human gut microbiota. We present the Culturable Genome Reference (CGR), a collection of 1,520 nonredundant, high-quality draft genomes generated from >6,000 bacteria cultivated from fecal samples of he...