Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units

• Published in: Early human development Vol. 88; no. Suppl 2; pp. S69 - S74
• Main Authors: Hornik, C.P., Fort, P., Clark, R.H., Watt, K., Benjamin, D.K., Smith, P.B., Manzoni, P., Jacqz-Aigrain, E., Kaguelidou, F., Cohen-Wolkowiez, M.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 01.05.2012
• Subjects: Advanced Basic Science; Early-onset sepsis; Female; Gram-Negative Bacteria - isolation & purification; Gram-Positive Bacteria - isolation & purification; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases - epidemiology; Infant, Premature, Diseases - microbiology; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Late-onset sepsis; Male; Neonatal and Perinatal Medicine; Risk Factors; Sepsis - epidemiology; Sepsis - microbiology; Sepsis - mortality; Very-low-birth-weight infants; Early-onset sepsis; Late-onset sepsis; Very-low-birth-weight infants

Very-low-birth-weight (VLBW, <1500 g birth weight) infants are at high risk for both early- and late-onset sepsis. Prior studies have observed a predominance of Gram-negative organisms as a cause of early-onset sepsis and Gram-positive organisms as a cause of late-onset sepsis. These reports are...