Phenome-wide association study identifies new clinical phenotypes associated with Staphylococcus aureus infections

• Published in: PloS one Vol. 19; no. 7; p. e0303395
• Main Authors: Allaire, Patrick, Elsayed, Noha S., Berg, Richard L., Rose, Warren, Shukla, Sanjay K.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 05.07.2024; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Age; Aged; Anemia; Aspirin; Biology and Life Sciences; Book publishing; Child; Chronic diseases; Chronic illnesses; Codes; Computer and Information Sciences; Criteria; Datasets; Deficiency diseases; Disease; Electronic health records; Female; Genetic aspects; Genome-Wide Association Study; Genotype & phenotype; Health aspects; Hospitalization; Human subjects; Humans; Infection; Iron deficiency; Male; Medical records; Medical research; Medical screening; Medicine and Health Sciences; Methicillin; Middle Aged; Mortality; Nutrient deficiency; Patients; Phenomics; Phenotype; Phenotypes; Risk Factors; Staphylococcal Infections - genetics; Staphylococcal Infections - microbiology; Staphylococcus aureus; Staphylococcus aureus - genetics; Staphylococcus aureus infections; Type 2 diabetes; Young Adult; United Kingdom

Phenome-Wide Association study (PheWAS) is a powerful tool designed to systematically screen clinical observations derived from medical records (phenotypes) for association with a variable of interest. Despite their usefulness, no systematic screening of phenotypes associated with Staphylococcus aur...