Effects of Rhazya Stricta plant organic extracts on human induced pluripotent stem cells derived neural stem cells

• Published in: PloS one Vol. 18; no. 7; p. e0288032
• Main Authors: Alawad, Abdullah Othman, Alagrafi, Faisal Sultan, Alfahad, Ahmed Jaman, Alamari, Hala Abdulrahman, Alghamdi, Fatimah Othman, Fallatah, Hussam Mokhtar, Aodah, Alhassan Hamood, Alyousef, Sultan Suleiman, Bakhrebah, Muhammed Adnan, Alanazi, Ibrahim Oqla, Fallatah, Mohannad Mokhtar
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 21.07.2023; Public Library of Science (PLoS)
• Subjects: Alkaloids - analysis; Alzheimer's disease; Alzheimers disease; Anticancer properties; Antihypertensives; Antioxidants - chemistry; Apocynaceae - chemistry; Bioactive compounds; Biological activity; Biological products; Biology and Life Sciences; Chemical composition; Chromatography; Ethylenediaminetetraacetic acid; Flavonoids; Gas chromatography; Health aspects; Herbal medicine; Humans; Induced Pluripotent Stem Cells; Mass spectrometry; Mass spectroscopy; Medical research; Natural products; Neural stem cells; Physical Sciences; Plant extracts; Plant Extracts - chemistry; Plant Leaves - chemistry; Pluripotency; Properties; Research and Analysis Methods; Scientific equipment and supplies industry; Scientific imaging; Stem cell research; Stem cells; Tannic acid; Saudi Arabia; United States; United States > US

Rhazya Stricta (R. stricta) has been employed as a natural remedy for several diseases for centuries. Numerous studies revealed that R. stricta extracts contain alkaloids, tannins, and flavonoids that possess antimicrobial, anticancer, antihypertensive, and antioxidant activities. In this study, we...