ADP‐ribosyltransferases, an update on function and nomenclature

• Published in: The FEBS journal Vol. 289; no. 23; pp. 7399 - 7410
• Main Authors: Lüscher, Bernhard, Ahel, Ivan, Altmeyer, Matthias, Ashworth, Alan, Bai, Peter, Chang, Paul, Cohen, Michael, Corda, Daniela, Dantzer, Françoise, Daugherty, Matthew D., Dawson, Ted M., Dawson, Valina L., Deindl, Sebastian, Fehr, Anthony R., Feijs, Karla L. H., Filippov, Dmitri V., Gagné, Jean‐Philippe, Grimaldi, Giovanna, Guettler, Sebastian, Hoch, Nicolas C., Hottiger, Michael O., Korn, Patricia, Kraus, W. Lee, Ladurner, Andreas, Lehtiö, Lari, Leung, Anthony K. L., Lord, Christopher J., Mangerich, Aswin, Matic, Ivan, Matthews, Jason, Moldovan, George‐Lucian, Moss, Joel, Natoli, Gioacchino, Nielsen, Michael L., Niepel, Mario, Nolte, Friedrich, Pascal, John, Paschal, Bryce M., Pawłowski, Krzysztof, Poirier, Guy G., Smith, Susan, Timinszky, Gyula, Wang, Zhao‐Qi, Yélamos, José, Yu, Xiaochun, Zaja, Roko, Ziegler, Mathias
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.12.2022; Wiley
• Subjects: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases - genetics; ADP-ribosylation; Antiviral agents; Biosynthesis; Cell death; Cellular Biology; Chromatin; DNA damage; Drug development; Gene regulation; Life Sciences; Mammals; MARylation; Metabolites; Nucleic acids; PARP; PARylation; posttranslational modification; Protein Biosynthesis; protein synthesis; Proteins; Reagents; Ribose; Ribosylation; Structural analysis; Subcellular Processes; Substrates; Therapeutic targets; therapeutics; transcription (genetics); PARP; MARylation; posttranslational modification; ADP-ribosylation; PARylation

ADP‐ribosylation, a modification of proteins, nucleic acids, and metabolites, confers broad functions, including roles in stress responses elicited, for example, by DNA damage and viral infection and is involved in intra‐ and extracellular signaling, chromatin and transcriptional regulation, protein...