The Potent Oxidant Anticancer Activity of Organoiridium Catalysts - Liu, Zhe; Romero-Canelón, Isolda; Qamar, Bushra; Hearn, Jessica M.; Habtemariam, Abraha; Barry, Nicolas P. E.; Pizarro, Ana M.; Clarkson, Guy J.; Sadler, Peter J. (Angewandte Chemie International Edition, 2014)
Keywords: anticancer drugs; Antineoplastic Agents - chemistry; biocatalysts; Cancer; Catalysis; Catalysts; Chemotherapy; Cisplatin - chemistry; Communications; Correlation; Drugs; Glutathione; Humans; hydride transfer; Hydrogen peroxide; Iridium; Iridium - chemistry; Ligands; Medical research; Models, Molecular; Organometallic Compounds - chemistry; Oxidants; Oxidizing agents; Pyridines; Reactive Oxygen Species; Structure-Activity Relationship; iridium; biocatalysts; hydride transfer; anticancer drugs; reactive oxygen species