High‐risk HPV types and head and neck cancer

• Published in: International journal of cancer Vol. 135; no. 7; pp. 1653 - 1661
• Main Authors: Michaud, Dominique S., Langevin, Scott M., Eliot, Melissa, Nelson, Heather H., Pawlita, Michael, McClean, Michael D., Kelsey, Karl T.
• Format: Journal Article
• Language: English
• Published: Hoboken, NJ Wiley-Blackwell 01.10.2014; Wiley Subscription Services, Inc
• Subjects: Antibodies, Viral - blood; Biological and medical sciences; Cancer; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - metabolism; Carcinoma, Squamous Cell - virology; Case-Control Studies; Cervical cancer; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Head & neck cancer; head and neck cancer; Head and Neck Neoplasms - diagnosis; Head and Neck Neoplasms - metabolism; Head and Neck Neoplasms - virology; HPV infection; Human papillomavirus; Human papillomavirus 16; Human papillomavirus 18; Humans; Male; Medical research; Medical sciences; Middle Aged; Multiple tumors. Solid tumors. Tumors in childhood (general aspects); Neoplasm Staging; Oral cancer; oropharyngeal cancer; Otorhinolaryngology (head neck, general aspects and miscellaneous); Otorhinolaryngology. Stomatology; Papillomaviridae - classification; Papillomaviridae - isolation & purification; Papillomavirus Infections - complications; Papillomavirus Infections - diagnosis; Papillomavirus Infections - virology; Prognosis; Risk Factors; Tumors; High risk; Oral cancer; Stomatology; Oropharynx cancer; Papovaviridae; Malignant tumor; Papillomavirus; Virus; Infection; HPV infection; Human papillomavirus; Cancerology; ENT disease; Head and neck cancer; Oral cavity disease; Pharynx disease; oropharyngeal cancer; Cancer; head and neck cancer; oral cancer

Although HPV16 has been strongly implicated in oropharyngeal carcinogenesis, the role of other high‐risk HPV types in the etiology of head and neck cancer remains unclear. To date, few data exist addressing the nature of the association between antibodies to oncogenic proteins of non‐HPV16 HPVs in r...