Acute tryptophan depletion in healthy subjects increases preferences for negative reciprocity

• Published in: PloS one Vol. 16; no. 3; p. e0249339
• Main Authors: Bengart, Paul, Gruendler, Theo, Vogt, Bodo
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 30.03.2021; Public Library of Science (PLoS)
• Subjects: Addictive behaviors; Adult; Affect - physiology; Amino acids; Behavior; Biology and Life Sciences; Choice Behavior - physiology; Decision making; Depletion; Drafting software; Economics; Experiments; Female; Games; Games, Experimental; Healthy Volunteers; Humans; Male; Medical research; Physical Sciences; Psychological aspects; Psychological research; Punishment; Questionnaires; Reciprocity; Rejection rate; Research and Analysis Methods; Serotonin; Serotonin - metabolism; Social Behavior; Social Sciences; Substance abuse treatment; Tryptophan; Tryptophan - metabolism; Young Adult; Germany

Reciprocity motivates to reward those who are kind (= positive reciprocity) and to punish those who are unkind (= negative reciprocity). The neurotransmitter serotonin (5-HT) modulates human behavior in numerous social situations, such as retaliation in response to perceived unfairness. In a placebo...